Detailed information NTG0705220

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: NLY76_RS07870
• Genome accession: NZ_CP100430
• Coordinates: 1623864..1624913 (-)
• Length: 349 a.a.
• NCBI ID: WP_004194592.1
• Uniprot ID: A0A0N0DPM5
• Organism: Streptococcus suis strain LSS42
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1618864..1629913

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NLY76_RS07850 (NLY76_07850)	trpB	1619228..1620403 (-)	1176	WP_044770249.1	tryptophan synthase subunit beta	-
NLY76_RS07855 (NLY76_07855)	-	1621390..1621917 (-)	528	WP_002942846.1	VanZ family protein	-
NLY76_RS07860 (NLY76_07860)	rlmN	1621914..1623026 (-)	1113	WP_029174969.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
NLY76_RS07865 (NLY76_07865)	-	1623035..1623676 (-)	642	WP_044685707.1	YutD-like domain-containing protein	-
NLY76_RS07870 (NLY76_07870)	sepM	1623864..1624913 (-)	1050	WP_004194592.1	SepM family pheromone-processing serine protease	Regulator
NLY76_RS07875 (NLY76_07875)	coaD	1624900..1625388 (-)	489	WP_044685708.1	pantetheine-phosphate adenylyltransferase	-
NLY76_RS07880 (NLY76_07880)	rsmD	1625378..1625917 (-)	540	WP_014638485.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NLY76_RS07885 (NLY76_07885)	-	1626225..1626947 (-)	723	WP_015647235.1	hypothetical protein	-
NLY76_RS07890 (NLY76_07890)	-	1627004..1627390 (-)	387	WP_044685709.1	rhodanese-like domain-containing protein	-
NLY76_RS07895 (NLY76_07895)	-	1627390..1627608 (-)	219	WP_004194736.1	YqgQ family protein	-
NLY76_RS07900 (NLY76_07900)	-	1627916..1628518 (-)	603	WP_044685710.1	response regulator	-
NLY76_RS07905 (NLY76_07905)	-	1628515..1629609 (-)	1095	WP_044685711.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37747.80 Da
• Isoelectric Point: 4.6112

>NTDB_id=705220 NLY76_RS07870 WP_004194592.1 1623864..1624913(-) (sepM) [Streptococcus suis strain LSS42]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=705220 NLY76_RS07870 WP_004194592.1 1623864..1624913(-) (sepM) [Streptococcus suis strain LSS42]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A0N0DPM5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605