Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NLG45_RS13280 Genome accession   NZ_CP100428
Coordinates   2676971..2677687 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain RMSA24     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2671971..2682687
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLG45_RS13260 (NLG45_13260) - 2673063..2674013 (+) 951 WP_000790324.1 LacI family DNA-binding transcriptional regulator -
  NLG45_RS13265 (NLG45_13265) - 2674162..2675646 (+) 1485 WP_000141426.1 sucrose-6-phosphate hydrolase -
  NLG45_RS13270 (NLG45_13270) - 2675643..2676602 (+) 960 WP_001253302.1 carbohydrate kinase -
  NLG45_RS13275 (NLG45_13275) - 2676790..2676899 (-) 110 Protein_2603 hypothetical protein -
  NLG45_RS13280 (NLG45_13280) agrA 2676971..2677687 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  NLG45_RS13285 (NLG45_13285) agrC 2677706..2678998 (-) 1293 WP_031929881.1 quorum-sensing sensor histidine kinase AgrC -
  NLG45_RS13290 (NLG45_13290) agrD 2679023..2679163 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  NLG45_RS13295 (NLG45_13295) agrB 2679160..2679729 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  NLG45_RS13300 (NLG45_13300) hld 2680019..2680099 (+) 81 WP_000046022.1 delta-hemolysin -
  NLG45_RS13305 (NLG45_13305) - 2680695..2681480 (-) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  NLG45_RS13310 (NLG45_13310) - 2681841..2682467 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=705173 NLG45_RS13280 WP_000688498.1 2676971..2677687(-) (agrA) [Staphylococcus aureus strain RMSA24]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=705173 NLG45_RS13280 WP_000688498.1 2676971..2677687(-) (agrA) [Staphylococcus aureus strain RMSA24]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996