Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexB   Type   Machinery gene
Locus tag   H7675_RS06175 Genome accession   NZ_AP023389
Coordinates   1227196..1230411 (-) Length   1071 a.a.
NCBI ID   WP_184004550.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain KUN-0012590     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1222196..1235411
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7675_RS06160 (KUN2590_11690) rpsU 1222298..1222474 (-) 177 WP_000048058.1 30S ribosomal protein S21 -
  H7675_RS06165 (KUN2590_11700) - 1222615..1223427 (-) 813 WP_023078819.1 transporter substrate-binding domain-containing protein -
  H7675_RS06170 (KUN2590_11710) rexA 1223567..1227196 (-) 3630 WP_031488380.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  H7675_RS06175 (KUN2590_11720) rexB 1227196..1230411 (-) 3216 WP_184004550.1 ATP-dependent nuclease subunit B Machinery gene
  H7675_RS06180 (KUN2590_11730) - 1230562..1231479 (+) 918 WP_012560586.1 neutral zinc metallopeptidase -
  H7675_RS06185 (KUN2590_11740) - 1231583..1232251 (-) 669 WP_031488382.1 ABC transporter ATP-binding protein -
  H7675_RS06190 (KUN2590_11750) - 1232261..1233337 (-) 1077 WP_184004554.1 FtsX-like permease family protein -
  H7675_RS06195 (KUN2590_11760) - 1233410..1233796 (-) 387 WP_002990406.1 YbgA family protein -
  H7675_RS06200 (KUN2590_11770) - 1233789..1234166 (-) 378 WP_002993028.1 OsmC family protein -

Sequence

Protein


Download         Length: 1071 a.a.        Molecular weight: 124171.13 Da        Isoelectric Point: 6.8336

>NTDB_id=70480 H7675_RS06175 WP_184004550.1 1227196..1230411(-) (rexB) [Streptococcus pyogenes strain KUN-0012590]
MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKEREVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQH
LDDTTLAMIFYRALMQLKPEDLPSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQ
QDYNQDSPLQSFARAIKLGLLNNQLSKTVVVIDGFSRFSAEEDYLLSLLNNNCQEVIIGSYVSQKAYQKSFIKGNIYEAS
LHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFEATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLY
EGYRYKDILVLLGDMDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKSGLFGCFDD
SDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQELFKSQKQLGALLVDKLILFLKKIRLAENM
QGLAQSQLEVEKNEEVWKRFTDILTSFHHIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFV
YAIGLTQSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELVLSVPTVINETFDDLSP
YLKELISFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINRQDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYR
LSTKPLSKEVIEVCFPKGIPLKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEPFD
NKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIKVIDQEKNFHLDMGNEILVHGIIDRIDQLS
DGSLGIVDYKSSANQFDIGTFYNGLSPQLVTYLAALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKAL
TYKGIFSEVEKEHLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQLKAITRFEAD
LDMGQARRLVTLPAKEKKECFLTLMRKESHL

Nucleotide


Download         Length: 3216 bp        

>NTDB_id=70480 H7675_RS06175 WP_184004550.1 1227196..1230411(-) (rexB) [Streptococcus pyogenes strain KUN-0012590]
ATGAAATTAATTTACACAGAGATGAGTTACTCGATGACAGAGATTTTGGTGAATGAAGCACGAAAAGCTGCTGACCAAGG
TTATCGAGTGTTCTATATTGCTCCAAATTCTCTTTCATTTGAAAAGGAAAGAGAAGTCTTAACCTTATTGCCTGAACGAG
GGACTTTTTCGATAATAGTTACCCGGTTCGTTCAAATGTCAAGGTATTTTACAGTTGAGAGCTCTCCTTCTAAGCAACAT
CTAGATGACACGACTTTGGCTATGATTTTTTATCGGGCCTTGATGCAATTAAAACCAGAAGATTTGCCGAGTTATGGTCG
TTTGCAAAATAATTCGGTTTTTATTGAACAACTAGTTGAGTTATATAAGGAATTAAAAAACGCACAATTAAGCGTACATG
ATTTAACAGGATTAGACCATCCTCAAAAACAAGAAGATCTTATTAAAATTATTGAGCTTGCAGAGACGATCATGATTCAG
CAAGATTATAATCAAGATAGTCCTCTACAATCTTTTGCAAGAGCAATTAAGTTAGGACTTTTAAATAACCAACTATCAAA
AACAGTTGTTGTTATTGATGGTTTTTCACGTTTTTCAGCTGAAGAGGATTATTTATTATCACTTTTAAATAACAACTGTC
AAGAGGTCATCATTGGCAGTTATGTGAGTCAAAAAGCTTATCAAAAATCTTTTATTAAGGGAAATATCTATGAGGCTAGC
CTTCATTTTTTGCAGGATTTGGCTCAAAAATACCATATCAAGCCGGTATTTGCGACCTCTAATCAAGTGTTTAAACCAGC
CTTTTCACGGCTAACACAATTATTTGAAGCAACTCATGATTTTTCACAAGTAGACTGGCAACTCCAAAAGAATGATCTTG
ATCACTTTAGCCTTTGGCAATGTCATCATCAAAAAGAGGAAATTGAACATGTAGCAAAATCCATTCGGCAAAAGCTATAT
GAAGGTTACCGTTATAAGGATATCTTAGTGTTGCTAGGAGATATGGATGCTTATCAATTACAAATTGGGCCTATCTTTGA
TAAGTTTGAAATCCCCTACTATTTAGGAAAAGCAGAGCCTATGGCTGCCCATCCATTAGTCCAATTTATAGAATCGCTCG
AACGAAGTCAGCGCTACAATTGGCGTCGTGAAGACATTTTAAACATGTTAAAATCAGGACTTTTTGGTTGTTTTGATGAT
AGTGATATTGATCGCTTTGAGGAATATACTCAGTTTGCAGATATTAAAGGGTTTACTAAATTTTCAAAGCCTTTTACCAT
TAACTCTTCTAGGCAGTATCCTCTTGACTTTTTAAATGAAATGAGACAAGACATCGTTTTACCTTTGCAAGAATTGTTTA
AGAGTCAAAAACAACTTGGTGCTTTACTTGTTGACAAATTAATACTTTTTTTAAAAAAGATTAGATTAGCTGAGAATATG
CAAGGTTTAGCACAGTCCCAATTAGAGGTGGAAAAAAACGAAGAAGTTTGGAAAAGGTTTACAGATATTTTGACTTCTTT
TCATCATATCTTTGGCCAAGAAAAATTACGGCTATCAGATTGCCTTGCTTTAATCAAAACGGGAATGAAATCAGCTCAGT
ATCGTGTTGTTCCAGCGACATTAGATGTTGTCACTATTAAATCTTATGACCTTGTTCAACCACATTCAAAACCTTTCGTT
TATGCAATTGGTCTAACTCAATCACATTTTCCTAAGCAAATTCACCATTCAGGACTACTTTCTGATCAAGAGCGTGCTAG
AATTAATGAAATAAGAAATTATCGTCATTTTGATATTGCTAGTGCCGAAAATAGTAAAAAAAACCATCAAACTGCGTTAT
CTCTGTTTAATGCTGCTACTAAAGAGTTAGTTCTTAGTGTTCCAACGGTAATCAACGAGACATTCGATGATCTATCTCCT
TATCTTAAAGAATTAATAAGCTTTGGGCTACCTCTTTTGGATAAAGGCAAAAACTATCTATCTTATGATAATAGCGATAT
TGGTAACTATAAAGCTCTCTTGTCACAAATTATTGCTATTAACCGACAAGATCTTATAGAAATGTCAGATCAAGATAAGA
TGTTTTGGACTGTTGTCTTACGTTATCTCAGGAAACAGTTAAGAAAGCAACAGCTAGAGTTACCTACTTCAGATTATCGT
TTATCAACAAAGCCTTTGTCTAAAGAAGTTATCGAGGTATGTTTTCCAAAGGGAATCCCTTTAAAGCTATCTGCAACTGC
TTTAACCGTTTTTTATAATAATCAGTACAACTATTTTTTGAAATATGTTTTGAATTTAAACAAAACAGAATCCATTCATC
CAGATTCCAGAATTCATGGTCAATACTTGCATCGTGTCTTTGAGCGGTTAATGAAAGATCACACGCAAGAACCGTTTGAT
AATAAGTTAAAACAAGCAATCTACCATACCAATCAAGAAAGTTTTTTTCAGCAGGTTTACCAAGATAATGCCGAGGCTGA
GTACAGTTTAGCTATACTAGAAGATATTGTTAGATCAACAGCACCTATCTTGCAACTTAACCAAAACATAAAGGTCATTG
ATCAAGAAAAGAACTTTCATCTGGATATGGGAAATGAGATATTAGTCCACGGGATCATTGATCGTATTGACCAGCTGAGC
GACGGTAGCTTGGGCATTGTTGACTATAAATCAAGCGCGAATCAATTTGATATTGGGACCTTTTATAATGGGTTGAGTCC
ACAACTAGTGACTTACCTCGCAGCCTTAAAACAGATCGCACCGCACGATATAAACCAATTATTTGGGGCTATGTACCTTC
ATTTGCAAGATCCTAAATTGGATCTAGTAACATTTAAACAAATTGATAACACATTAGTGGAGAGTATCTATAAAGCGTTG
ACCTATAAAGGTATTTTTTCAGAAGTCGAAAAAGAGCATCTATCTACTGGTGCTTACCAAACCAAAAATGCTCTTTATTC
CAATGACGAATTGGAAACACTTTTAAATTATAACAAGTACCTCTATCTTAAAGCTGCTAAACACATTAAAAAGGGACATT
TTTTGATTAATCCTTATACAAGCGATGGTAAGACAGTTCAAGGAGATCAATTAAAAGCCATTACCCGTTTTGAAGCAGAT
CTTGACATGGGACAGGCAAGGCGACTAGTGACTCTCCCTGCTAAGGAGAAAAAAGAGTGCTTTTTAACATTAATGAGAAA
GGAGAGCCACTTGTGA

Domains

Predicted by InterProScan.

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(743-1020)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexB Streptococcus pneumoniae R6

41.341

100

0.415

Multiple sequence alignment