Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   PDI73_RS06510 Genome accession   NZ_CP115479
Coordinates   1377376..1378746 (-) Length   456 a.a.
NCBI ID   WP_033899080.1    Uniprot ID   -
Organism   Lactococcus lactis strain EP2     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1372376..1383746
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PDI73_RS06495 (PDI73_06495) - 1373547..1374980 (-) 1434 WP_277730100.1 6-phospho-beta-glucosidase -
  PDI73_RS06500 (PDI73_06500) yidD 1375103..1375369 (-) 267 WP_012898265.1 membrane protein insertion efficiency factor YidD -
  PDI73_RS06505 (PDI73_06505) - 1375486..1377228 (-) 1743 WP_010906088.1 1-deoxy-D-xylulose-5-phosphate synthase -
  PDI73_RS06510 (PDI73_06510) ciaH 1377376..1378746 (-) 1371 WP_033899080.1 HAMP domain-containing sensor histidine kinase Regulator
  PDI73_RS06515 (PDI73_06515) ciaR 1378839..1379507 (-) 669 WP_021722129.1 response regulator transcription factor Regulator
  PDI73_RS06520 (PDI73_06520) - 1379685..1380659 (-) 975 WP_003130365.1 LacI family DNA-binding transcriptional regulator -
  PDI73_RS06525 (PDI73_06525) - 1380812..1383067 (-) 2256 WP_277730101.1 glycoside hydrolase family 65 protein -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 51314.88 Da        Isoelectric Point: 9.4537

>NTDB_id=704796 PDI73_RS06510 WP_033899080.1 1377376..1378746(-) (ciaH) [Lactococcus lactis strain EP2]
MKKIIKKVKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLIEAANNQLGMNNSQD
SGYYGPNNSVIFYDSEGKSFIPSAGSNANISTNFGMSLLQKTMKFNENQINTIQTVSVKNPYGDNWHYRYLTTSQFIITN
TDGTVTPVYAQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSVIISLYLANWTLKPILAAYEKQKEFVENASHELRTPLAI
LQNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKF
SGHLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKART
RQKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIIRIRVDSTISNPAKIFQKL

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=704796 PDI73_RS06510 WP_033899080.1 1377376..1378746(-) (ciaH) [Lactococcus lactis strain EP2]
TTGAAGAAAATAATTAAAAAAGTTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAATTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTCTTTTTGATAGAAGCAGCGAATAATCAATTAGGAATGAATAATTCGCAAGAT
AGTGGCTATTACGGTCCCAATAATAGTGTAATTTTTTATGATTCAGAGGGTAAAAGTTTCATACCTTCAGCGGGTTCAAA
TGCAAATATAAGTACAAACTTTGGCATGAGCCTTCTGCAAAAAACAATGAAATTTAACGAAAATCAAATTAACACTATTC
AAACTGTTTCTGTAAAAAATCCTTATGGAGATAATTGGCACTATCGTTATCTGACAACATCACAATTTATTATTACAAAT
ACTGATGGAACAGTAACTCCGGTTTATGCACAAATTTTTTCAAATGTTGACCAAATTCAAGATGCCATGAGCCGAGCCAT
GTGGGTCATTGTGACAACAATGATTACTTTCTGGCTTCTGTCAGTAATTATTAGTCTATATCTTGCAAACTGGACATTAA
AACCAATTTTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATC
TTGCAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACTGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTT
ATCAGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGC
CAGAGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTT
TCAGGCCATTTGAAATTAGATGGAACGATTAATTTGGACCAAGCCCTGATTAAACAATTGCTGACCATCTTATTTGATAA
TGCTCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGGGGATTCTTAGTTTTTGCTGTCG
CCGATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACG
CGTCAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGA
AGATAATAAACCTAAAGGTACAAAATTCATTATTAGAATTCGTGTGGATAGCACAATTTCAAATCCTGCAAAAATTTTCC
AAAAGTTGTAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(223-289)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(333-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

48.837

94.298

0.461
  ciaH Streptococcus pneumoniae Rx1

44.098

98.465

0.434
  ciaH Streptococcus pneumoniae D39

44.098

98.465

0.434
  ciaH Streptococcus pneumoniae R6

44.098

98.465

0.434
  ciaH Streptococcus pneumoniae TIGR4

44.098

98.465

0.434