Detailed information NTG0704572

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: NKZ66_RS10205
• Genome accession: NZ_CP100336
• Coordinates: 2038614..2041067 (-)
• Length: 817 a.a.
• NCBI ID: WP_024417811.1
• Uniprot ID: -
• Organism: Streptococcus suis strain STC81
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 2033614..2046067

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NKZ66_RS10190 (NKZ66_10190)	hslO	2036044..2036910 (+)	867	WP_013730589.1	Hsp33 family molecular chaperone HslO	-
NKZ66_RS10195 (NKZ66_10195)	dusB	2036903..2037907 (+)	1005	WP_024417813.1	tRNA dihydrouridine synthase DusB	-
NKZ66_RS10200 (NKZ66_10200)	-	2038004..2038495 (-)	492	WP_024417812.1	adenylyltransferase/cytidyltransferase family protein	-
NKZ66_RS10205 (NKZ66_10205)	clpC	2038614..2041067 (-)	2454	WP_024417811.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
NKZ66_RS10210 (NKZ66_10210)	-	2041071..2041523 (-)	453	WP_024417810.1	CtsR family transcriptional regulator	-
NKZ66_RS10215 (NKZ66_10215)	traF	2041691..2042050 (+)	360	WP_024417809.1	conjugal transfer protein TraF	-
NKZ66_RS10220 (NKZ66_10220)	-	2042122..2042538 (-)	417	WP_204101646.1	LPXTG cell wall anchor domain-containing protein	-
NKZ66_RS10225 (NKZ66_10225)	-	2042468..2044525 (-)	2058	WP_201343725.1	Cna B-type domain-containing protein	-

Sequence

Protein

• Length: 817 a.a.
• Molecular weight: 90475.02 Da
• Isoelectric Point: 6.2908

>NTDB_id=704572 NKZ66_RS10205 WP_024417811.1 2038614..2041067(-) (clpC) [Streptococcus suis strain STC81]
MKISTGLQRVFEDAQLVAQRYACDYLETWHVLLSFVINHDTVAGAVLAEYPISISDYEHATFVVTDKVYREELDSFRILP
SSKRLDETASFAKKIAEVVKAKELGTEHLFMAMLLDKRSTASQILDKVGFCFEDSDDKFRFLDLRKNLEARAGFTKEDLK
AIRSVMKGGKAKPTNMGQMMGMPPAPQSGGLEDYTRDLTALAREGKIEPVIGRDAEIARMIQILSRKTKNNPVLVGDAGV
GKTALALGLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQTEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGQAAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQAEETGLTSIDKALMDKKYKTVSKLLIKTKEDAEASQNYDLEV
TEEDVLETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTETHMQDVVKVMIKPLLTVTAEKGITLKLQPSALKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGDLTTGST
LKVGVKGEELKFDVVKG

Nucleotide

• Length: 2454 bp

>NTDB_id=704572 NKZ66_RS10205 WP_024417811.1 2038614..2041067(-) (clpC) [Streptococcus suis strain STC81]
ATGAAAATTTCAACTGGTTTACAGCGGGTTTTTGAAGATGCCCAGTTAGTGGCCCAACGCTATGCCTGTGATTACTTGGA
AACCTGGCATGTTCTCTTGTCTTTCGTTATCAACCATGATACAGTCGCTGGTGCTGTTTTGGCAGAATATCCTATTTCAA
TTTCTGACTATGAACATGCAACTTTTGTTGTGACCGACAAGGTCTATCGTGAAGAGTTGGATAGTTTTCGTATTTTACCA
TCTTCTAAACGTTTGGATGAAACAGCTAGTTTTGCCAAGAAAATTGCAGAAGTCGTCAAGGCTAAGGAGCTGGGAACGGA
ACATTTGTTTATGGCTATGTTGTTGGACAAGCGGTCAACAGCTAGTCAGATTTTGGACAAGGTAGGTTTTTGTTTTGAAG
ACTCAGATGATAAGTTTCGTTTCTTGGATTTGCGTAAAAACTTGGAGGCACGTGCGGGATTTACCAAAGAGGACCTTAAA
GCTATCCGCAGTGTGATGAAGGGTGGCAAAGCCAAACCTACCAATATGGGACAGATGATGGGAATGCCCCCAGCACCTCA
AAGTGGTGGATTAGAAGACTACACTCGTGATTTGACAGCTTTGGCGCGTGAAGGGAAGATTGAACCTGTCATCGGTCGAG
ACGCTGAGATTGCACGGATGATCCAAATTCTATCACGTAAAACCAAGAATAACCCAGTTCTAGTTGGTGATGCTGGTGTC
GGAAAAACTGCGCTTGCTTTGGGTCTTGCTCAACGTGTTGCTGCAGGTGATGTCCCTGTCAGCTTGGCTAAGATGCGGGT
TTTGGAACTTGACTTGATGAACGTTATCGCTGGAACTCGTTTCCGTGGTGATTTCGAAGAGCGGATGAATAATATCATCA
ACGACATCGAGGAAGATGGTCAGGTCATCCTTTTCATCGATGAGTTGCATACCATTATGGGTTCTGGCTCGGGGATTGAT
TCGACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTTGCTCGTGGCACCCTCCGTACGGTCGGAGCGACGACTCAGAC
AGAGTACCAAAAGCATATCGAGAAGGATGCAGCCCTGGTTCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTGG
AAGATAGCATTGCCATTTTGACTGGTTTAAAAGGTACTTTTGAAAAATACCACAGGGTCCGTATTGGACAAGCAGCTGTA
GAGACTGCTGTGACCTACGCTAAGCGGTATTTGACCAGTAAAAACCTGCCAGATTCAGCCATTGATCTGCTGGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGGCAGGCTGAGGAAACAGGACTGACGAGCATAGACAAGGCCTTGATGGATA
AAAAATATAAGACTGTCAGCAAGCTTTTGATTAAAACGAAAGAAGATGCCGAGGCTAGTCAAAACTATGACCTTGAAGTA
ACAGAAGAAGATGTTTTAGAAACACTTAGCCGCTTGTCAGGTATCCCAGTAGCCAAGCTTAGCCAATCAGATACTAAGAA
GTATCTGAATCTGGAAGCAGAATTGCATAAGCGTGTGATTGGGCAGGAAGAAGCTATTTCTGCTGTTAGCAGAGCTATTC
GCCGTAATCAGTCAGGGATTCGTACAGGTCGCAGACCGATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTCGGCAAG
ACAGAGCTTGCTAAAGCTTTGGCAGAGGTTCTCTTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCTGAGTATAT
GGAGAAATTTGCGGCCAGCCGTCTCAATGGAGCGCCTCCAGGCTACGTGGGCTATGAAGAAGGTGGCGAATTGACAGAAA
AAGTTCGTAATAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTCAATGTTCTCTTG
CAGGTCTTGGATGATGGTGTCTTGACGGACAGTAAGGGACGTAAGGTTGATTTCTCAAATACTATTATTATCATGACGTC
AAACCTTGGAGCAACAGCCCTTCGTGATGATAAGACAGTTGGTTTTGGTGCCCTTGATTTATCTAAGGACCATAAGGAAG
TGGAGAAACGCATTTTTGAGGAATTGAAAAAAGCCTATCGTCCAGAATTTATCAACCGTATTGACGAGAAAGTTGTCTTC
CATAGCCTAACGGAAACTCATATGCAGGATGTTGTCAAGGTCATGATTAAACCTTTGCTTACGGTAACAGCTGAGAAAGG
AATTACTCTTAAACTGCAACCGTCAGCCCTTAAGTTATTGGCTAAGCAAGGTTATGACCCAGAAATGGGGGCTCGTCCTC
TTCGTAGACTCTTGCAGACCAAGTTGGAAGATCCGTTGGCAGAGATGTTGCTCCGTGGTGACTTGACTACTGGTTCGACC
TTGAAGGTTGGGGTCAAGGGTGAAGAGCTCAAGTTTGATGTGGTAAAGGGATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• AAA lid domain (AAA_lid_9) (372-457)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-129)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-56)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	71.779	99.755	0.716
clpC	Streptococcus pneumoniae D39	71.779	99.755	0.716
clpC	Streptococcus pneumoniae TIGR4	71.779	99.755	0.716
clpC	Streptococcus mutans UA159	66.585	99.633	0.663
clpC	Streptococcus thermophilus LMD-9	63.962	100	0.656
clpC	Streptococcus thermophilus LMG 18311	64.38	100	0.655
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.222	100	0.503
clpC	Bacillus subtilis subsp. subtilis str. 168	43.353	100	0.443