Detailed information NTG0704455

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: NKZ65_RS08805
• Genome accession: NZ_CP100332
• Coordinates: 1751699..1752748 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain STC84
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1746699..1757748

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NKZ65_RS08785 (NKZ65_08785)	trpB	1747015..1748190 (-)	1176	WP_204101559.1	tryptophan synthase subunit beta	-
NKZ65_RS08790 (NKZ65_08790)	-	1749225..1749752 (-)	528	WP_002942846.1	VanZ family protein	-
NKZ65_RS08795 (NKZ65_08795)	rlmN	1749749..1750861 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
NKZ65_RS08800 (NKZ65_08800)	-	1750870..1751511 (-)	642	WP_014638483.1	YutD-like domain-containing protein	-
NKZ65_RS08805 (NKZ65_08805)	sepM	1751699..1752748 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
NKZ65_RS08810 (NKZ65_08810)	coaD	1752735..1753223 (-)	489	WP_015647233.1	pantetheine-phosphate adenylyltransferase	-
NKZ65_RS08815 (NKZ65_08815)	rsmD	1753213..1753752 (-)	540	WP_024388284.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NKZ65_RS08820 (NKZ65_08820)	-	1754059..1754781 (-)	723	WP_044684680.1	hypothetical protein	-
NKZ65_RS08825 (NKZ65_08825)	-	1754838..1755224 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
NKZ65_RS08830 (NKZ65_08830)	-	1755224..1755442 (-)	219	WP_041179287.1	YqgQ family protein	-
NKZ65_RS08835 (NKZ65_08835)	-	1755750..1756352 (-)	603	WP_015647237.1	response regulator transcription factor	-
NKZ65_RS08840 (NKZ65_08840)	-	1756349..1757443 (-)	1095	WP_044684682.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=704455 NKZ65_RS08805 WP_012775295.1 1751699..1752748(-) (sepM) [Streptococcus suis strain STC84]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=704455 NKZ65_RS08805 WP_012775295.1 1751699..1752748(-) (sepM) [Streptococcus suis strain STC84]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATTTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605