Detailed information NTG0704435

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: NKZ65_RS02530
• Genome accession: NZ_CP100332
• Coordinates: 487891..490119 (-)
• Length: 742 a.a.
• NCBI ID: WP_254369375.1
• Uniprot ID: -
• Organism: Streptococcus suis strain STC84
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 482891..495119

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NKZ65_RS02510 (NKZ65_02510)	-	483259..483702 (+)	444	WP_012774999.1	GNAT family N-acetyltransferase	-
NKZ65_RS02515 (NKZ65_02515)	ileS	483713..486502 (+)	2790	WP_012775000.1	isoleucine--tRNA ligase	-
NKZ65_RS02520 (NKZ65_02520)	-	486881..487189 (-)	309	WP_002938710.1	DUF1827 family protein	-
NKZ65_RS02525 (NKZ65_02525)	-	487244..487705 (-)	462	WP_002938708.1	NUDIX hydrolase	-
NKZ65_RS02530 (NKZ65_02530)	clpE	487891..490119 (-)	2229	WP_254369375.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
NKZ65_RS02535 (NKZ65_02535)	-	490343..490573 (+)	231	WP_002938704.1	DUF1797 family protein	-
NKZ65_RS02540 (NKZ65_02540)	-	490699..491388 (+)	690	WP_002938702.1	amino acid ABC transporter permease	-
NKZ65_RS02545 (NKZ65_02545)	-	491381..492115 (+)	735	WP_002943067.1	amino acid ABC transporter ATP-binding protein	-
NKZ65_RS02550 (NKZ65_02550)	-	492245..493093 (+)	849	WP_015646548.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
NKZ65_RS02555 (NKZ65_02555)	-	494532..494825 (+)	294	WP_002938694.1	hypothetical protein	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 82668.03 Da
• Isoelectric Point: 5.2798

>NTDB_id=704435 NKZ65_RS02530 WP_254369375.1 487891..490119(-) (clpE) [Streptococcus suis strain STC84]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGEHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYNPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide

• Length: 2229 bp

>NTDB_id=704435 NKZ65_RS02530 WP_254369375.1 487891..490119(-) (clpE) [Streptococcus suis strain STC84]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAACGCTATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGGAAAAATCGC
GAACAGACTCCTCCTACTCAAGCCGGTGAGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTTGACGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCGCCCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACCATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAAGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTAACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGGAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAGGAAGATATTCCACTCATTACTGAAAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAACAATTAGCTATCGAACTCTTCGGTTCGGCAGA
CAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATG
TAGGCTATGAGGAGGCTGGACAATTGACAGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGTCGTCTGACAGATGGACAAGGTCGGACAGT
CAGCTTCAAAGATACTATTATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGT
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACAATCCAAAGATGG
GAGCTCGTCCACTACGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (476-639)

• AAA lid domain (AAA_lid_9) (291-389)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (647-721)

• ATPase family associated with various cellular activities (AAA) (AAA) (153-272)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.095	100	0.834
clpE	Streptococcus pneumoniae D39	82.095	100	0.834
clpE	Streptococcus pneumoniae R6	82.095	100	0.834
clpE	Streptococcus pneumoniae TIGR4	82.095	100	0.834
clpE	Streptococcus mutans UA159	82.109	100	0.829
clpC	Lactococcus lactis subsp. cremoris KW2	77.655	97.709	0.759
clpC	Bacillus subtilis subsp. subtilis str. 168	52.308	87.601	0.458
clpC	Streptococcus thermophilus LMD-9	48.089	84.636	0.407
clpC	Streptococcus mutans UA159	48.397	84.097	0.407
clpC	Streptococcus thermophilus LMG 18311	47.771	84.636	0.404
clpC	Streptococcus pneumoniae D39	47.68	84.232	0.402
clpC	Streptococcus pneumoniae TIGR4	47.68	84.232	0.402
clpC	Streptococcus pneumoniae Rx1	47.68	84.232	0.402
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.656	84.636	0.395