Detailed information NTG0703414

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: NHG72_RS12880
• Genome accession: NZ_CP100041
• Coordinates: 2651170..2652333 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain B3
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2646170..2657333

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NHG72_RS12860 (NHG72_12845)	-	2646610..2647806 (+)	1197	WP_032876154.1	glycosyltransferase	-
NHG72_RS12865 (NHG72_12850)	-	2647939..2649015 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
NHG72_RS12870 (NHG72_12855)	-	2649114..2650295 (-)	1182	WP_032876157.1	LCP family protein	-
NHG72_RS12875 (NHG72_12860)	-	2650300..2650947 (-)	648	WP_007614107.1	YigZ family protein	-
NHG72_RS12880 (NHG72_12865)	degS	2651170..2652333 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
NHG72_RS12885 (NHG72_12870)	degU	2652410..2653099 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
NHG72_RS12890 (NHG72_12875)	-	2653197..2654045 (+)	849	WP_032876160.1	DegV family protein	-
NHG72_RS12895 (NHG72_12880)	comFA	2654154..2655539 (+)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
NHG72_RS12900 (NHG72_12885)	-	2655597..2655881 (+)	285	WP_003151389.1	competence protein ComFB	-
NHG72_RS12905 (NHG72_12890)	comFC	2655887..2656576 (+)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
NHG72_RS12910 (NHG72_12895)	-	2656650..2657069 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=703414 NHG72_RS12880 WP_007407484.1 2651170..2652333(+) (degS) [Bacillus velezensis strain B3]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=703414 NHG72_RS12880 WP_007407484.1 2651170..2652333(+) (degS) [Bacillus velezensis strain B3]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951