Detailed information NTG0703365

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: NHG71_RS18395
• Genome accession: NZ_CP100040
• Coordinates: 3713680..3714843 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain B1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3708680..3719843

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NHG71_RS18375 (NHG71_18345)	-	3709120..3710316 (+)	1197	WP_032876154.1	glycosyltransferase	-
NHG71_RS18380 (NHG71_18350)	-	3710449..3711525 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
NHG71_RS18385 (NHG71_18355)	-	3711624..3712805 (-)	1182	WP_032876157.1	LCP family protein	-
NHG71_RS18390 (NHG71_18360)	-	3712810..3713457 (-)	648	WP_007614107.1	YigZ family protein	-
NHG71_RS18395 (NHG71_18365)	degS	3713680..3714843 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
NHG71_RS18400 (NHG71_18370)	degU	3714920..3715609 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
NHG71_RS18405 (NHG71_18375)	-	3715707..3716555 (+)	849	WP_032876160.1	DegV family protein	-
NHG71_RS18410 (NHG71_18380)	comFA	3716664..3718049 (+)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
NHG71_RS18415 (NHG71_18385)	-	3718107..3718391 (+)	285	WP_003151389.1	competence protein ComFB	-
NHG71_RS18420 (NHG71_18390)	comFC	3718397..3719086 (+)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
NHG71_RS18425 (NHG71_18395)	-	3719160..3719579 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=703365 NHG71_RS18395 WP_007407484.1 3713680..3714843(+) (degS) [Bacillus velezensis strain B1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=703365 NHG71_RS18395 WP_007407484.1 3713680..3714843(+) (degS) [Bacillus velezensis strain B1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951