Detailed information NTG0703187

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: NG812_RS01925
• Genome accession: NZ_CP099987
• Coordinates: 377926..380376 (+)
• Length: 816 a.a.
• NCBI ID: WP_207784790.1
• Uniprot ID: A0AAX3NF06
• Organism: Lactococcus garvieae strain FUA009
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 372926..385376

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NG812_RS01900 (NG812_01895)	-	373833..374345 (+)	513	WP_003134000.1	adenine phosphoribosyltransferase	-
NG812_RS01905 (NG812_01900)	rpoE	374483..375043 (+)	561	WP_003134001.1	DNA-directed RNA polymerase subunit delta	-
NG812_RS01910 (NG812_01905)	mltG	375149..376864 (+)	1716	WP_393187181.1	endolytic transglycosylase MltG	-
NG812_RS01915 (NG812_01910)	greA	376889..377362 (+)	474	WP_003134005.1	transcription elongation factor GreA	-
NG812_RS01920 (NG812_01915)	-	377484..377936 (+)	453	WP_003134006.1	CtsR family transcriptional regulator	-
NG812_RS01925 (NG812_01920)	clpC	377926..380376 (+)	2451	WP_207784790.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
NG812_RS01930 (NG812_01925)	hpf	380500..381057 (+)	558	WP_003134010.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
NG812_RS01935 (NG812_01930)	pflB	381305..383638 (+)	2334	WP_003134012.1	formate C-acetyltransferase	-
NG812_RS01940 (NG812_01935)	coaE	383871..384476 (+)	606	WP_003134016.1	dephospho-CoA kinase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 91119.37 Da
• Isoelectric Point: 6.1755

>NTDB_id=703187 NG812_RS01925 WP_207784790.1 377926..380376(+) (clpC) [Lactococcus garvieae strain FUA009]
MKFNEKDFTPQVVRVLEKSVDYAHKFNYAWVESSHLLAALAEVPASLAFTLLNSEKIDLEEMLIDIEDFSSQVKTKKSEI
KLSPRVETIIEQARALAQNNDKNRIGTEHLLYMLLANEASFAGQLLREQNINIVNLRKKLEQKAYLRVPERRKAVTPASK
RNLSGKVSETTTTPTLDTVSTDLTKAAREGKLDPMIGREREVERLIHILSRRTKNNPVLVGEPGVGKSAIIEGFATRVAA
GNVPVGLRGSRIMALNMAMVVAGTKFRGEFEDRLTAIVDEVTHDKDVIVFIDELHTIIGAGGGMDSVNDASNILKPALAR
GEFQLIGATTYQEYQKYIEKDEALERRFARVNVEEPSEKETVAILQGLKEKFEAYHAVKFEEGALERAVSLSNRYMPSRR
LPDKAIDLLDEAAAKVKITSKTNYTKLDELKAELKAEELKLQQAVVALDIVEAQGIEKDIERLTHKIDNFTVSENDNPLV
EESDIYAVVSNLTGIPLQQMTKTESERLINLEKELHKRVVGQEEAISAVSRAIRRARSGIADTRRPLGSFMFLGPTGVGK
TELAKALAESVFGSEENMIRVDMSEFMEKFSTSRLIGAPPGYVGYDEGGQLTEQVRNKPYSVILLDEVEKAHPDIFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATAIRDDKTVGFGAKSISTDYAAMKARIMEELKKQYRPEFLNRIDETIVF
HSLTEKEIEQVVKIMSKSLVSRLKDQNITVKFTPAALKVIADKGFDPEYGARPLRKALQREVEDTLSEQLLAGEIHPGDT
ISIGSSNKKIRISVID

Nucleotide

• Length: 2451 bp

>NTDB_id=703187 NG812_RS01925 WP_207784790.1 377926..380376(+) (clpC) [Lactococcus garvieae strain FUA009]
ATGAAATTTAATGAAAAGGACTTTACACCACAAGTTGTTAGAGTGCTTGAGAAGTCTGTCGACTATGCGCATAAGTTTAA
CTACGCTTGGGTAGAAAGCTCGCACCTATTGGCTGCCTTGGCTGAGGTTCCGGCTTCATTGGCATTTACGCTACTTAATT
CAGAAAAGATTGATTTGGAAGAGATGTTAATCGACATCGAAGATTTTTCAAGTCAAGTGAAGACAAAAAAATCAGAAATA
AAGCTTAGCCCAAGAGTTGAAACGATTATTGAGCAAGCCCGAGCATTGGCTCAAAATAACGATAAAAACCGTATTGGGAC
AGAACATCTCTTGTATATGCTGTTGGCGAATGAAGCCAGCTTTGCAGGACAACTTTTACGTGAGCAAAACATTAATATTG
TTAACCTCCGTAAAAAGTTAGAGCAAAAAGCATATTTACGAGTGCCAGAACGCCGTAAAGCGGTGACTCCAGCCTCAAAA
AGAAATCTGTCGGGGAAGGTGTCCGAAACAACAACAACGCCTACTTTAGATACAGTCTCGACAGATTTGACAAAAGCAGC
GCGTGAAGGCAAGCTTGATCCAATGATTGGGAGAGAGCGTGAAGTCGAACGTCTTATCCATATTTTGAGTCGCCGAACAA
AGAATAATCCCGTTCTTGTTGGTGAACCAGGCGTTGGTAAGTCAGCCATTATTGAAGGCTTTGCGACACGTGTGGCTGCA
GGAAATGTTCCTGTAGGTTTACGCGGCAGTCGTATCATGGCCTTGAATATGGCGATGGTCGTAGCGGGGACGAAGTTCCG
TGGTGAATTTGAAGATCGTTTGACAGCTATTGTGGATGAAGTGACACATGATAAAGATGTTATCGTCTTTATCGATGAAC
TCCATACTATTATTGGTGCTGGGGGAGGCATGGACTCTGTCAATGATGCCTCAAACATTTTAAAACCCGCATTAGCACGT
GGCGAGTTTCAACTTATTGGTGCTACTACTTATCAAGAATATCAAAAATATATTGAAAAAGATGAAGCTCTGGAGCGCCG
TTTTGCCCGTGTCAATGTCGAAGAACCCTCAGAAAAAGAAACGGTTGCGATTTTACAAGGCTTGAAAGAAAAATTTGAAG
CTTACCATGCGGTTAAATTTGAAGAAGGGGCTTTGGAGCGTGCCGTTAGCTTGAGTAATCGCTACATGCCAAGTCGTCGT
CTGCCAGACAAAGCCATTGATCTTCTTGATGAAGCAGCGGCCAAAGTTAAAATCACGAGTAAAACAAATTACACCAAGCT
AGACGAGTTAAAAGCAGAATTAAAAGCGGAAGAGCTGAAATTACAACAAGCAGTTGTTGCTCTTGATATTGTTGAAGCAC
AAGGAATTGAAAAAGATATTGAAAGATTAACACACAAAATTGATAATTTTACAGTATCGGAAAATGATAATCCTTTGGTC
GAAGAAAGCGATATTTATGCTGTTGTTTCTAACCTTACAGGAATTCCGCTCCAACAAATGACGAAAACAGAAAGTGAACG
TCTGATTAACTTAGAAAAAGAGTTACATAAACGTGTGGTCGGACAGGAAGAAGCGATTTCGGCTGTTTCTCGTGCTATAA
GACGTGCGCGTTCAGGTATTGCTGATACGAGACGTCCTCTGGGTTCATTTATGTTCCTTGGTCCGACAGGGGTGGGGAAA
ACAGAGCTTGCTAAAGCTTTAGCGGAAAGTGTCTTTGGGAGTGAAGAGAACATGATTCGCGTAGACATGAGTGAATTTAT
GGAAAAATTCTCGACATCGCGTCTTATCGGAGCACCTCCAGGGTATGTAGGTTACGACGAAGGAGGACAATTGACAGAAC
AAGTCCGTAATAAGCCTTATTCTGTTATTCTCCTTGATGAAGTTGAAAAAGCCCATCCTGACATTTTCAATATCATGTTG
CAAATTTTGGATGACGGTTTCGTTACAGATACCAAAGGGCGGAAGGTTGATTTCCGAAATACAATCATCATTATGACATC
CAACTTAGGCGCAACGGCTATTCGTGATGATAAAACGGTTGGTTTTGGGGCTAAATCAATTTCAACAGATTATGCAGCCA
TGAAAGCAAGAATCATGGAAGAACTGAAGAAACAGTACCGTCCAGAATTTCTTAACCGTATCGATGAAACCATCGTTTTC
CATTCACTGACAGAAAAAGAGATTGAACAAGTCGTGAAAATCATGAGTAAATCTCTTGTATCACGTTTGAAAGATCAAAA
TATCACAGTGAAATTTACCCCTGCTGCCTTGAAAGTTATTGCTGATAAAGGATTTGATCCTGAGTATGGTGCACGTCCGT
TGCGTAAAGCGCTACAACGGGAGGTTGAAGACACGCTCAGTGAGCAATTGCTTGCAGGCGAAATTCATCCGGGGGATACG
ATTTCTATTGGGTCTTCTAATAAAAAGATTAGAATAAGTGTTATTGATTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (357-445)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-349)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (22-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	70.798	99.877	0.707
clpC	Streptococcus thermophilus LMG 18311	49.819	100	0.505
clpC	Streptococcus thermophilus LMD-9	49.819	100	0.505
clpC	Streptococcus pneumoniae TIGR4	49.395	100	0.5
clpC	Streptococcus pneumoniae Rx1	49.274	100	0.499
clpC	Streptococcus pneumoniae D39	49.274	100	0.499
clpC	Streptococcus mutans UA159	47.488	100	0.487
clpC	Bacillus subtilis subsp. subtilis str. 168	48.31	97.917	0.473
clpE	Streptococcus mutans UA159	46.875	78.431	0.368