Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexB   Type   Machinery gene
Locus tag   KUN2590_RS07045 Genome accession   NZ_AP023387
Coordinates   1336859..1340074 (-) Length   1071 a.a.
NCBI ID   WP_011054337.1    Uniprot ID   P0CZ55
Organism   Streptococcus pyogenes strain NIH34     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1331859..1345074
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KUN2590_RS07030 (SPNIH34_13450) rpsU 1331961..1332137 (-) 177 WP_000048058.1 30S ribosomal protein S21 -
  KUN2590_RS07035 (SPNIH34_13460) - 1332278..1333090 (-) 813 WP_011054339.1 transporter substrate-binding domain-containing protein -
  KUN2590_RS07040 (SPNIH34_13470) rexA 1333230..1336859 (-) 3630 WP_301182343.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  KUN2590_RS07045 (SPNIH34_13480) rexB 1336859..1340074 (-) 3216 WP_011054337.1 ATP-dependent nuclease subunit B Machinery gene
  KUN2590_RS07050 (SPNIH34_13490) - 1340225..1341141 (+) 917 Protein_1351 neutral zinc metallopeptidase -
  KUN2590_RS07055 (SPNIH34_13500) - 1341246..1341914 (-) 669 WP_011017620.1 ABC transporter ATP-binding protein -
  KUN2590_RS07060 (SPNIH34_13510) - 1341924..1343000 (-) 1077 WP_011054335.1 FtsX-like permease family protein -
  KUN2590_RS07065 (SPNIH34_13520) - 1343073..1343459 (-) 387 WP_002990406.1 YbgA family protein -
  KUN2590_RS07070 (SPNIH34_13530) - 1343452..1343829 (-) 378 WP_011054334.1 OsmC family protein -

Sequence

Protein


Download         Length: 1071 a.a.        Molecular weight: 124333.20 Da        Isoelectric Point: 6.8336

>NTDB_id=70294 KUN2590_RS07045 WP_011054337.1 1336859..1340074(-) (rexB) [Streptococcus pyogenes strain NIH34]
MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKEREVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQH
LDDTTLAMIFYRALMQLKPEDLPSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQ
QDYNQDSPLQSFARAIKLGLLNNQLSKTVVVIDGFSRFSAEEDYLLSLLNNNCQEVIIGSYVSQKAYQKSFIKGNIYEAS
LHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFEATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLY
EGYRYKDILVLLGDMDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKSGLFGCFDD
SDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQELFKSQKQLGASLVDKLILFLKKIRLAENM
QGLAQSQLEVEKNEEVWKRFTDILTSFHHIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFV
YAIGLTQSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELVLSVPTVINETFDDLSP
YLKELINFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINRQDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYR
LSTKSLSKEVIEVCFPKRIPLKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEPFD
NKLKQAIYHTNQESFFQQIYQDNAEAEYSLAILEDIVRSTAPILQLNQNIQVIDQEKNFHLDMGNEILVHGIIDRIDQLS
DGSLGIVDYKSSANQFDIGTFYNGLSPQLVTYLAALKQITPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKAL
TYKGIFSEVEKEHLSTGAYQTKNALYSNDELETLLNYNRYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQLKAITRFEAD
LDMGQARRLVTLPAKEKKECFLTLMRKESHL

Nucleotide


Download         Length: 3216 bp        

>NTDB_id=70294 KUN2590_RS07045 WP_011054337.1 1336859..1340074(-) (rexB) [Streptococcus pyogenes strain NIH34]
ATGAAATTAATTTACACAGAGATGAGTTACTCGATGACAGAGATTTTGGTGAATGAAGCACGAAAAGCTGCTGACCAAGG
TTATCGAGTGTTCTATATTGCTCCAAATTCTCTTTCATTTGAAAAGGAAAGAGAAGTCTTAACCTTATTGCCTGAACGAG
GGACTTTTTCGATAATAGTAACCCGGTTCGTTCAAATGTCAAGGTATTTTACAGTTGAGAGCTCTCCTTCTAAGCAACAT
CTAGATGACACGACTTTGGCTATGATTTTTTATCGGGCCTTGATGCAATTAAAACCAGAAGATTTGCCGAGTTATGGTCG
TTTGCAAAATAATTCGGTTTTTATTGAACAACTAGTTGAGTTATATAAGGAATTAAAAAACGCACAATTAAGCGTACATG
ATTTAACAGGGTTAGATCATCCTCAAAAACAAGAAGATCTTATTAAAATTATTGAGCTTGCAGAGACGATCATGATTCAG
CAAGATTATAATCAAGATAGTCCTCTACAATCTTTTGCAAGAGCAATTAAGTTAGGACTTTTAAATAACCAACTATCAAA
AACAGTTGTTGTTATTGATGGTTTTTCACGTTTTTCAGCTGAAGAGGATTATTTATTATCACTTTTAAATAACAACTGTC
AAGAGGTCATCATTGGCAGTTATGTGAGTCAAAAAGCTTATCAAAAATCTTTTATTAAGGGAAATATCTATGAGGCTAGC
CTTCATTTTTTGCAAGATTTGGCTCAAAAATACCATATCAAGCCGGTATTTGCGACCTCTAATCAAGTGTTTAAACCAGC
CTTTTCACGGCTAACACAATTATTTGAAGCAACTCATGATTTTTCACAAGTAGACTGGCAACTCCAAAAGAATGATCTTG
ATCACTTTAGCCTTTGGCAATGTCATCATCAAAAAGAGGAAATTGAACATGTAGCAAAATCCATTCGGCAAAAGCTATAT
GAAGGTTACCGTTATAAGGATATCTTAGTGTTGCTAGGAGATATGGATGCTTATCAATTACAAATTGGGCCTATCTTTGA
TAAGTTTGAAATCCCCTACTATTTAGGAAAAGCAGAGCCTATGGCTGCCCACCCATTAGTCCAATTTATAGAATCGCTCG
AACGAAGTCAGCGCTATAATTGGCGTCGTGAAGACATTTTAAACATGTTAAAATCAGGACTTTTTGGTTGTTTTGATGAT
AGTGATATTGATCGCTTTGAGGAATATACTCAGTTTGCAGATATTAAAGGGTTTACTAAATTTTCAAAGCCTTTTACCAT
TAACTCTTCTAGGCAGTATCCTCTTGACTTTTTAAATGAAATGAGACAAGACATCGTTTTACCTTTGCAAGAATTGTTTA
AGAGTCAAAAACAACTTGGTGCTTCACTTGTTGACAAATTAATACTTTTTTTAAAAAAGATTAGATTAGCTGAGAATATG
CAAGGTTTAGCACAGTCCCAATTAGAGGTGGAAAAAAACGAAGAAGTTTGGAAAAGGTTTACAGATATTTTGACTTCTTT
TCATCATATCTTTGGCCAAGAAAAATTACGACTATCAGATTGCCTTGCTTTAATCAAAACAGGAATGAAATCAGCTCAGT
ATCGTGTTGTTCCAGCGACATTAGATGTTGTCACCATTAAATCTTATGACCTTGTTCAACCACATTCAAAACCTTTCGTT
TATGCAATTGGTCTAACTCAATCACATTTTCCTAAGCAAATTCACCATTCAGGACTACTTTCTGATCAAGAGCGTGCTAG
AATTAATGAAATAAGAAATTATCGTCATTTTGATATTGCTAGTGCCGAAAATAGTAAAAAAAACCATCAAACTGCGTTAT
CTCTGTTTAATGCTGCCACTAAGGAGTTAGTTCTTAGTGTTCCAACGGTAATCAACGAGACATTCGATGATCTATCTCCT
TATCTTAAAGAATTAATAAACTTTGGGTTACCTCTTTTGGATAAAGGCAAAAACTATCTATCTTATGATAATAGCGATAT
TGGTAACTATAAAGCTCTCTTGTCACAAATTATTGCTATTAACCGACAAGATCTTATAGAAATGTCAGATCAAGATAAGA
TGTTTTGGACTGTTGTCTTGCGTTATCTCAGGAAACAGTTAAGAAAGCAACAGCTAGAGTTACCTACTTCAGATTATCGT
TTATCAACAAAGTCTTTGTCTAAAGAAGTTATCGAGGTATGTTTTCCAAAGAGAATCCCTTTAAAGCTATCTGCAACTGC
TTTAACCGTTTTTTATAATAATCAGTACAACTATTTTTTGAAATATGTTTTGAATTTAAACAAAACAGAATCCATTCATC
CAGATTCCAGAATTCATGGTCAATACTTGCATCGTGTCTTTGAGCGGTTAATGAAAGATCACACGCAAGAACCGTTTGAT
AATAAATTAAAACAAGCAATCTACCATACCAATCAAGAAAGTTTTTTTCAGCAGATTTACCAAGATAATGCCGAGGCTGA
GTACAGTTTAGCTATACTAGAAGATATTGTTAGATCAACAGCACCTATCTTGCAACTTAACCAAAACATACAGGTCATTG
ATCAAGAAAAGAACTTTCATCTGGATATGGGAAATGAGATATTAGTCCACGGGATCATTGATCGTATTGACCAGCTGAGC
GACGGTAGCTTGGGCATTGTTGACTATAAATCAAGCGCGAATCAATTTGATATTGGGACCTTTTATAATGGGTTGAGTCC
ACAACTAGTGACTTACCTCGCAGCCTTAAAACAGATCACACCGCACGATATAAACCAATTATTTGGGGCTATGTACCTTC
ATTTGCAAGATCCTAAATTGGATCTAGTAACATTTAAACAAATTGATAACACATTAGTGGAGAGTATCTATAAAGCGTTG
ACTTATAAAGGTATTTTTTCAGAAGTCGAAAAAGAGCATCTATCTACTGGTGCTTACCAAACCAAAAATGCTCTTTATTC
CAATGACGAATTGGAAACACTTTTAAATTATAACAGGTACCTCTATCTTAAAGCTGCTAAACACATTAAAAAGGGACATT
TTTTGATTAATCCTTATACAAGCGATGGTAAGACAGTTCAAGGAGATCAATTAAAAGCCATTACCCGTTTTGAAGCAGAT
CTTGACATGGGACAGGCAAGGCGACTAGTGACTCTCCCTGCTAAGGAGAAAAAAGAGTGCTTTTTAACATTAATGAGAAA
GGAGAGCCACTTGTGA

Domains

Predicted by InterProScan.

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(743-1020)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0CZ55

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexB Streptococcus pneumoniae R6

41.434

100

0.416

Multiple sequence alignment