Detailed information NTG0070284

Bioinformatically predicted

Overview

• Name: xerS
• Type: Machinery gene
• Locus tag: KUN2590_RS05510
• Genome accession: NZ_AP023387
• Coordinates: 1029079..1030149 (-)
• Length: 356 a.a.
• NCBI ID: WP_002984598.1
• Uniprot ID: P0DH45
• Organism: Streptococcus pyogenes strain NIH34
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1024079..1035149

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KUN2590_RS05490 (SPNIH34_10450)	citX	1024657..1025235 (+)	579	WP_011054513.1	citrate lyase holo-[acyl-carrier protein] synthase	-
KUN2590_RS05495 (SPNIH34_10460)	-	1025250..1026644 (+)	1395	WP_002991774.1	oxaloacetate decarboxylase subunit alpha	-
KUN2590_RS05500 (SPNIH34_10470)	citC	1026755..1027807 (-)	1053	WP_011054514.1	[citrate (pro-3S)-lyase] ligase	-
KUN2590_RS05505 (SPNIH34_10480)	-	1027896..1028378 (-)	483	WP_002984600.1	PASTA domain-containing protein	-
KUN2590_RS05510 (SPNIH34_10490)	xerS	1029079..1030149 (-)	1071	WP_002984598.1	tyrosine recombinase XerS	Machinery gene
KUN2590_RS05515 (SPNIH34_10500)	-	1030619..1031317 (+)	699	WP_002993300.1	XRE family transcriptional regulator	-
KUN2590_RS05520 (SPNIH34_10510)	ffh	1031452..1033014 (-)	1563	WP_011054515.1	signal recognition particle protein	-
KUN2590_RS05525 (SPNIH34_10520)	-	1033029..1033361 (-)	333	WP_002989745.1	putative DNA-binding protein	-
KUN2590_RS05530 (SPNIH34_10530)	-	1033459..1034157 (-)	699	WP_002989743.1	GntR family transcriptional regulator	-

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 41471.57 Da
• Isoelectric Point: 9.5552

>NTDB_id=70284 KUN2590_RS05510 WP_002984598.1 1029079..1030149(-) (xerS) [Streptococcus pyogenes strain NIH34]
MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKEYKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLE
AFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDS
VNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDAT
KSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL

Nucleotide

• Length: 1071 bp

>NTDB_id=70284 KUN2590_RS05510 WP_002984598.1 1029079..1030149(-) (xerS) [Streptococcus pyogenes strain NIH34]
ATGAGACGCGAATTATTACTAGAAAAAATTGAAACCTACAAGGCTATCATGCCTTGGTATGTTTTAGATTATTACCAATC
CAAATTAGCTGTTCCATACAGCTTTACCACCTTATATGAGTATTTAAAAGAATACAAACGCTTTTTTGATTGGCTGATGG
ATGCTGATTTAACGCAGGCGCCAAAGATTGCTGATATTGACTTGAGCACGCTTGAGCACCTTACCAAGAAGGATTTAGAG
GCCTTTGTGCTTTATTTGCGGGAACGACCTTCTCTCAACACCTATTCCACCAAAGAGGGGCTTTCTCAAACCACTATTAA
TCGGACCTTGTCTGCCCTATCAAGCCTTTACAAGTACTTGACTGAAGAGGTTGAAAATGACCAAGGGGAGCCTTATTTTT
ATCGGAATGTTATGAAAAAAGTGTCAACAAAAAAGAAAAAAGAAACCCTGGCTTCCAGAGCGGAAAATATTAAGCAGAAA
CTGTTTTTAGGTGATGAAACTCTAGCTTTCTTGGATTATGTGGATAAGGAATATGAGCAAAAATTGTCTAATCGTGCCAA
ATCTTCTTTCCGTAAAAATAAGGAGAGGGATTTGGCTATTATTGCTCTACTACTTGCTTCTGGTGTTCGTTTGTCTGAAG
CAGTGAATCTTGATTTAAAAGATGTCAATCTAAATATGATGATTATCGAAGTTATTCGCAAAGGCGGAAAACGTGATTCA
GTCAATGTAGCAGGTTTTGCGAAAGGTTATTTGGAGTCTTATTTAGCTGTTCGTCAGAGACGTTACAAGGCTGAAAAACA
GGATCTTGCTTTCTTTTTAACAGAATACCGTGGCGTTCCAAATCGAATGGATGCTTCTAGTATAGAAAAGATGGTTGGCA
AGTACTCTGAGGATTTTAAAATTCGTGTGACTCCTCATAAATTGCGTCATACGCTAGCGACAAGACTATATGATGCTACT
AAATCTCAGGTGTTAGTTAGTCATCAATTAGGCCATTCCTCTACTCAAGTCACGGATCTTTATACCCATATTGTCAATGA
TGAGCAAAAAAATGCTTTAGATAACCTTTAA

Domains

Predicted by InterProScan.

• Phage integrase family (Phage_integrase) (177-344)

• Phage integrase, N-terminal SAM-like domain (Phage_int_SAM_4) (33-122)

3D structure

• AlphaFold DB: P0DH45

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
xerS	Streptococcus pneumoniae R6	80.618	100	0.806