Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   KUN2590_RS04725 Genome accession   NZ_AP023387
Coordinates   885954..886742 (-) Length   262 a.a.
NCBI ID   WP_021340822.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NIH34     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 880954..891742
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KUN2590_RS04710 (SPNIH34_08830) - 883448..884068 (-) 621 WP_011054596.1 DUF3862 domain-containing protein -
  KUN2590_RS04715 (SPNIH34_08840) - 884431..885519 (-) 1089 WP_011054595.1 site-specific integrase -
  KUN2590_RS04720 (SPNIH34_08850) - 885639..885944 (-) 306 WP_011106738.1 membrane protein -
  KUN2590_RS04725 (SPNIH34_08860) irvR 885954..886742 (-) 789 WP_021340822.1 S24 family peptidase Regulator
  KUN2590_RS04730 (SPNIH34_08870) - 887114..887260 (+) 147 WP_011054593.1 hypothetical protein -
  KUN2590_RS04735 (SPNIH34_08890) - 887394..888173 (-) 780 WP_011054591.1 hypothetical protein -
  KUN2590_RS04740 (SPNIH34_08900) - 888230..888436 (+) 207 WP_011054590.1 hypothetical protein -
  KUN2590_RS04745 (SPNIH34_08910) - 888425..888811 (-) 387 WP_011054589.1 hypothetical protein -
  KUN2590_RS04750 (SPNIH34_08920) - 888885..889124 (+) 240 WP_011054588.1 helix-turn-helix domain-containing protein -
  KUN2590_RS04755 (SPNIH34_08940) - 889340..889549 (-) 210 WP_002984292.1 hypothetical protein -
  KUN2590_RS04760 (SPNIH34_08950) - 889700..889939 (-) 240 WP_011054586.1 hypothetical protein -
  KUN2590_RS04765 (SPNIH34_08960) - 890106..890291 (+) 186 WP_011054585.1 helix-turn-helix domain-containing protein -
  KUN2590_RS04770 (SPNIH34_08970) - 890369..890665 (+) 297 WP_011054584.1 MerR family transcriptional regulator -
  KUN2590_RS09865 (SPNIH34_08980) - 890662..890796 (+) 135 WP_002995985.1 hypothetical protein -
  KUN2590_RS04775 (SPNIH34_08990) - 890812..891126 (+) 315 WP_011054583.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29992.22 Da        Isoelectric Point: 9.0535

>NTDB_id=70279 KUN2590_RS04725 WP_021340822.1 885954..886742(-) (irvR) [Streptococcus pyogenes strain NIH34]
MARGRGKLTPQDEEYKKIISAKINSLLLENNLKQGHLADALEIPRSSFNEYVKGNSLPNPGNVQKIADYFGLMKSDIDPR
FAPRKKNHELKIPTSPLVKKITTTVVELKVPRKQKVLDFATEQLKEQKNKITSIEKKLYEYKVYEKLSAGTGYGYFGDGN
YDTVFYDEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGIYAVEWDGQTYIKKVYREKGGLRLVSLNKKYNDKF
APFSEGPRIIGEIVGNFMPKEY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=70279 KUN2590_RS04725 WP_021340822.1 885954..886742(-) (irvR) [Streptococcus pyogenes strain NIH34]
ATGGCAAGAGGACGAGGGAAATTAACACCTCAAGACGAGGAATACAAAAAGATAATTTCTGCTAAAATTAACAGTTTATT
GCTAGAAAACAATTTAAAACAAGGACATTTAGCTGATGCATTGGAAATTCCACGAAGTAGTTTTAATGAATATGTCAAAG
GAAATTCCTTACCTAATCCTGGTAACGTTCAAAAGATAGCTGATTATTTCGGGTTAATGAAGTCTGATATAGATCCTAGA
TTTGCACCTCGTAAGAAAAATCACGAACTCAAAATCCCTACTTCTCCACTCGTCAAAAAAATAACCACAACAGTTGTAGA
ATTAAAGGTTCCTCGTAAACAAAAAGTTTTAGACTTTGCAACAGAACAATTGAAAGAGCAAAAAAACAAAATTACTTCGA
TAGAGAAAAAACTATATGAATACAAAGTCTATGAGAAACTTTCCGCAGGTACAGGTTATGGATATTTTGGTGATGGGAAC
TATGATACTGTTTTTTACGACGAAGAATTAGATTACGATTTTGCCTCTTGGGTTTTTGGTGATTCTATGGAACCAACTTA
TCTGAATGGTGAGGTTGTGCTTATAAAACAAACTGGCTTTGATTATGAAGGTGGCATCTATGCCGTAGAGTGGGACGGAC
AAACCTATATTAAGAAAGTTTACAGAGAAAAGGGTGGCTTGCGCCTTGTGTCCTTAAATAAAAAATACAATGACAAGTTT
GCTCCTTTTAGTGAAGGCCCTCGTATAATAGGGGAAATTGTCGGTAACTTTATGCCTAAAGAGTACTGA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(168-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

38.158

100

0.443

Multiple sequence alignment