Detailed information NTG0702322

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: NIZ13_RS14285
• Genome accession: NZ_CP099898
• Coordinates: 2905898..2906527 (-)
• Length: 209 a.a.
• NCBI ID: WP_000839162.1
• Uniprot ID: A0A2T3RS91
• Organism: Escherichia albertii strain 147_1_TBG_A
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
ICE	2891989..2906327	2905898..2906527	flank	-429

Gene organization within MGE regions

Location: 2891989..2906527

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NIZ13_RS14215 (NIZ13_14210)	-	2892052..2894532 (+)	2481	WP_025237254.1	exonuclease	-
NIZ13_RS14220 (NIZ13_14215)	-	2894599..2894850 (+)	252	WP_000273158.1	DUF4224 domain-containing protein	-
NIZ13_RS14225 (NIZ13_14220)	-	2894819..2895838 (+)	1020	WP_024227504.1	tyrosine-type recombinase/integrase	-
NIZ13_RS14230 (NIZ13_14225)	yccA	2896247..2896906 (+)	660	WP_000375136.1	FtsH protease modulator YccA	-
NIZ13_RS14235 (NIZ13_14230)	tusE	2896998..2897327 (+)	330	WP_024164819.1	sulfurtransferase TusE	-
NIZ13_RS14240 (NIZ13_14235)	yccX	2897324..2897602 (-)	279	WP_000048219.1	acylphosphatase	-
NIZ13_RS14245 (NIZ13_14240)	rlmI	2897696..2898886 (+)	1191	WP_059215636.1	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	-
NIZ13_RS14250 (NIZ13_14245)	hspQ	2898944..2899261 (+)	318	WP_001295356.1	heat shock protein HspQ	-
NIZ13_RS14255 (NIZ13_14250)	-	2899306..2899719 (-)	414	WP_002462360.1	CoA-binding protein	-
NIZ13_RS14260 (NIZ13_14255)	-	2899892..2900554 (+)	663	WP_000847777.1	DUF2057 family protein	-
NIZ13_RS14265 (NIZ13_14260)	mgsA	2900650..2901108 (+)	459	WP_000424182.1	methylglyoxal synthase	-
NIZ13_RS14270 (NIZ13_14265)	helD	2901140..2903194 (-)	2055	WP_059215651.1	DNA helicase IV	-
NIZ13_RS14275 (NIZ13_14270)	-	2903317..2903763 (+)	447	WP_001261228.1	YccF domain-containing protein	-
NIZ13_RS14280 (NIZ13_14275)	yccS	2903773..2905938 (+)	2166	WP_072244615.1	YccS family putative transporter	-
NIZ13_RS14285 (NIZ13_14280)	sxy/tfoX	2905898..2906527 (-)	630	WP_000839162.1	TfoX/Sxy family DNA transformation protein	Regulator

Sequence

Protein

• Length: 209 a.a.
• Molecular weight: 24291.21 Da
• Isoelectric Point: 9.0264

>NTDB_id=702322 NIZ13_RS14285 WP_000839162.1 2905898..2906527(-) (sxy/tfoX) [Escherichia albertii strain 147_1_TBG_A]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVNDTVFAMVADGELYLRACEQSVQYCVKHPPVWLTYKKCGRPVTLN
YYRVDESLWRNQQKLVRLSKYSLDAALKEKCTRNNLQRLKDLPNMSYHLEAILGEVGIKDVRTLRILGAKMCWLRLRQHN
SQVTEKILFMLEGAIIDIHEAALPVARRQELAEWAESIVPKPEFPTEPE

Nucleotide

• Length: 630 bp

>NTDB_id=702322 NIZ13_RS14285 WP_000839162.1 2905898..2906527(-) (sxy/tfoX) [Escherichia albertii strain 147_1_TBG_A]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAGTCACAAGAATACCTTGCAACGTTAGGCACCATTGAATATCGATCGCT
GTTTGGCAGTTACAGTTTGACGGTTAACGATACGGTATTTGCGATGGTTGCTGATGGTGAGTTGTATCTACGGGCTTGTG
AACAAAGCGTACAGTACTGTGTAAAACATCCGCCAGTCTGGCTGACATATAAAAAGTGCGGCCGACCCGTGACTCTCAAT
TACTACCGGGTTGATGAAAGTCTATGGCGTAACCAACAGAAATTAGTTCGCTTGTCGAAATATTCCCTGGATGCTGCGCT
GAAAGAGAAATGTACGCGCAACAATCTCCAGCGACTGAAAGATTTGCCGAATATGTCTTATCACCTGGAGGCGATTCTCG
GTGAAGTGGGGATCAAGGATGTGCGGACTTTACGGATCCTTGGCGCAAAAATGTGCTGGTTGCGACTACGTCAGCATAAT
AGCCAGGTGACGGAGAAGATCTTATTCATGCTTGAAGGCGCAATTATTGATATTCATGAAGCAGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCTGAATGGGCTGAATCTATTGTGCCGAAACCGGAGTTTCCGACGGAACCTGAGTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (117-194)

• TfoX N-terminal domain (TfoX_N) (14-106)

3D structure

• AlphaFold DB: A0A2T3RS91

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Escherichia coli BW25113 strain K-12	90.431	100	0.904