Detailed information NTG0702233

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: NIZ18_RS14760
• Genome accession: NZ_CP099887
• Coordinates: 2991661..2992290 (-)
• Length: 209 a.a.
• NCBI ID: WP_000839162.1
• Uniprot ID: A0A2T3RS91
• Organism: Escherichia albertii strain 208_2_GWG_B
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
ICE	2977752..2992090	2991661..2992290	flank	-429

Gene organization within MGE regions

Location: 2977752..2992290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NIZ18_RS14690 (NIZ18_14685)	-	2977815..2980295 (+)	2481	WP_149506592.1	exonuclease	-
NIZ18_RS14695 (NIZ18_14690)	-	2980362..2980613 (+)	252	WP_024237931.1	DUF4224 domain-containing protein	-
NIZ18_RS14700 (NIZ18_14695)	-	2980582..2981601 (+)	1020	WP_024227504.1	tyrosine-type recombinase/integrase	-
NIZ18_RS14705 (NIZ18_14700)	yccA	2982010..2982669 (+)	660	WP_000375136.1	FtsH protease modulator YccA	-
NIZ18_RS14710 (NIZ18_14705)	tusE	2982761..2983090 (+)	330	WP_024164819.1	sulfurtransferase TusE	-
NIZ18_RS14715 (NIZ18_14710)	yccX	2983087..2983365 (-)	279	WP_000048219.1	acylphosphatase	-
NIZ18_RS14720 (NIZ18_14715)	rlmI	2983459..2984649 (+)	1191	WP_059215636.1	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	-
NIZ18_RS14725 (NIZ18_14720)	hspQ	2984707..2985024 (+)	318	WP_001295356.1	heat shock protein HspQ	-
NIZ18_RS14730 (NIZ18_14725)	-	2985069..2985482 (-)	414	WP_002462360.1	CoA-binding protein	-
NIZ18_RS14735 (NIZ18_14730)	-	2985655..2986317 (+)	663	WP_000847777.1	DUF2057 family protein	-
NIZ18_RS14740 (NIZ18_14735)	mgsA	2986413..2986871 (+)	459	WP_000424182.1	methylglyoxal synthase	-
NIZ18_RS14745 (NIZ18_14740)	helD	2986903..2988957 (-)	2055	WP_059215651.1	DNA helicase IV	-
NIZ18_RS14750 (NIZ18_14745)	-	2989080..2989526 (+)	447	WP_001261228.1	YccF domain-containing protein	-
NIZ18_RS14755 (NIZ18_14750)	yccS	2989536..2991701 (+)	2166	WP_072244615.1	YccS family putative transporter	-
NIZ18_RS14760 (NIZ18_14755)	sxy/tfoX	2991661..2992290 (-)	630	WP_000839162.1	TfoX/Sxy family DNA transformation protein	Regulator

Sequence

Protein

• Length: 209 a.a.
• Molecular weight: 24291.21 Da
• Isoelectric Point: 9.0264

>NTDB_id=702233 NIZ18_RS14760 WP_000839162.1 2991661..2992290(-) (sxy/tfoX) [Escherichia albertii strain 208_2_GWG_B]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVNDTVFAMVADGELYLRACEQSVQYCVKHPPVWLTYKKCGRPVTLN
YYRVDESLWRNQQKLVRLSKYSLDAALKEKCTRNNLQRLKDLPNMSYHLEAILGEVGIKDVRTLRILGAKMCWLRLRQHN
SQVTEKILFMLEGAIIDIHEAALPVARRQELAEWAESIVPKPEFPTEPE

Nucleotide

• Length: 630 bp

>NTDB_id=702233 NIZ18_RS14760 WP_000839162.1 2991661..2992290(-) (sxy/tfoX) [Escherichia albertii strain 208_2_GWG_B]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAGTCACAAGAATACCTTGCAACGTTAGGCACCATTGAATATCGATCGCT
GTTTGGCAGTTACAGTTTGACGGTTAACGATACGGTATTTGCGATGGTTGCTGATGGTGAGTTGTATCTACGGGCTTGTG
AACAAAGCGTACAGTACTGTGTAAAACATCCGCCAGTCTGGCTGACATATAAAAAGTGCGGCCGACCCGTGACTCTCAAT
TACTACCGGGTTGATGAAAGTCTATGGCGTAACCAACAGAAATTAGTTCGCTTGTCGAAATATTCCCTGGATGCTGCGCT
GAAAGAGAAATGTACGCGCAACAATCTCCAGCGACTGAAAGATTTGCCGAATATGTCTTATCACCTGGAGGCGATTCTCG
GTGAAGTGGGGATCAAGGATGTGCGGACTTTACGGATCCTTGGCGCAAAAATGTGCTGGTTGCGACTACGTCAGCATAAT
AGCCAGGTGACGGAGAAGATCTTATTCATGCTTGAAGGCGCAATTATTGATATTCATGAAGCAGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCTGAATGGGCTGAATCTATTGTGCCGAAACCGGAGTTTCCGACGGAACCTGAGTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (117-194)

• TfoX N-terminal domain (TfoX_N) (14-106)

3D structure

• AlphaFold DB: A0A2T3RS91

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Escherichia coli BW25113 strain K-12	90.431	100	0.904