Detailed information NTG0702144

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: NIZ22_RS14765
• Genome accession: NZ_CP099877
• Coordinates: 2991113..2991742 (-)
• Length: 209 a.a.
• NCBI ID: WP_000839162.1
• Uniprot ID: A0A2T3RS91
• Organism: Escherichia albertii strain 247_2_EW_B
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
ICE	2977204..2991542	2991113..2991742	flank	-429

Gene organization within MGE regions

Location: 2977204..2991742

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NIZ22_RS14695 (NIZ22_14690)	-	2977267..2979747 (+)	2481	WP_149506592.1	exonuclease	-
NIZ22_RS14700 (NIZ22_14695)	-	2979814..2980065 (+)	252	WP_024237931.1	DUF4224 domain-containing protein	-
NIZ22_RS14705 (NIZ22_14700)	-	2980034..2981053 (+)	1020	WP_024227504.1	tyrosine-type recombinase/integrase	-
NIZ22_RS14710 (NIZ22_14705)	yccA	2981462..2982121 (+)	660	WP_000375136.1	FtsH protease modulator YccA	-
NIZ22_RS14715 (NIZ22_14710)	tusE	2982213..2982542 (+)	330	WP_024164819.1	sulfurtransferase TusE	-
NIZ22_RS14720 (NIZ22_14715)	yccX	2982539..2982817 (-)	279	WP_000048219.1	acylphosphatase	-
NIZ22_RS14725 (NIZ22_14720)	rlmI	2982911..2984101 (+)	1191	WP_059215636.1	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	-
NIZ22_RS14730 (NIZ22_14725)	hspQ	2984159..2984476 (+)	318	WP_001295356.1	heat shock protein HspQ	-
NIZ22_RS14735 (NIZ22_14730)	-	2984521..2984934 (-)	414	WP_002462360.1	CoA-binding protein	-
NIZ22_RS14740 (NIZ22_14735)	-	2985107..2985769 (+)	663	WP_000847777.1	DUF2057 family protein	-
NIZ22_RS14745 (NIZ22_14740)	mgsA	2985865..2986323 (+)	459	WP_000424182.1	methylglyoxal synthase	-
NIZ22_RS14750 (NIZ22_14745)	helD	2986355..2988409 (-)	2055	WP_059215651.1	DNA helicase IV	-
NIZ22_RS14755 (NIZ22_14750)	-	2988532..2988978 (+)	447	WP_001261228.1	YccF domain-containing protein	-
NIZ22_RS14760 (NIZ22_14755)	yccS	2988988..2991153 (+)	2166	WP_072244615.1	YccS family putative transporter	-
NIZ22_RS14765 (NIZ22_14760)	sxy/tfoX	2991113..2991742 (-)	630	WP_000839162.1	TfoX/Sxy family DNA transformation protein	Regulator

Sequence

Protein

• Length: 209 a.a.
• Molecular weight: 24291.21 Da
• Isoelectric Point: 9.0264

>NTDB_id=702144 NIZ22_RS14765 WP_000839162.1 2991113..2991742(-) (sxy/tfoX) [Escherichia albertii strain 247_2_EW_B]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVNDTVFAMVADGELYLRACEQSVQYCVKHPPVWLTYKKCGRPVTLN
YYRVDESLWRNQQKLVRLSKYSLDAALKEKCTRNNLQRLKDLPNMSYHLEAILGEVGIKDVRTLRILGAKMCWLRLRQHN
SQVTEKILFMLEGAIIDIHEAALPVARRQELAEWAESIVPKPEFPTEPE

Nucleotide

• Length: 630 bp

>NTDB_id=702144 NIZ22_RS14765 WP_000839162.1 2991113..2991742(-) (sxy/tfoX) [Escherichia albertii strain 247_2_EW_B]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAGTCACAAGAATACCTTGCAACGTTAGGCACCATTGAATATCGATCGCT
GTTTGGCAGTTACAGTTTGACGGTTAACGATACGGTATTTGCGATGGTTGCTGATGGTGAGTTGTATCTACGGGCTTGTG
AACAAAGCGTACAGTACTGTGTAAAACATCCGCCAGTCTGGCTGACATATAAAAAGTGCGGCCGACCCGTGACTCTCAAT
TACTACCGGGTTGATGAAAGTCTATGGCGTAACCAACAGAAATTAGTTCGCTTGTCGAAATATTCCCTGGATGCTGCGCT
GAAAGAGAAATGTACGCGCAACAATCTCCAGCGACTGAAAGATTTGCCGAATATGTCTTATCACCTGGAGGCGATTCTCG
GTGAAGTGGGGATCAAGGATGTGCGGACTTTACGGATCCTTGGCGCAAAAATGTGCTGGTTGCGACTACGTCAGCATAAT
AGCCAGGTGACGGAGAAGATCTTATTCATGCTTGAAGGCGCAATTATTGATATTCATGAAGCAGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCTGAATGGGCTGAATCTATTGTGCCGAAACCGGAGTTTCCGACGGAACCTGAGTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (117-194)

• TfoX N-terminal domain (TfoX_N) (14-106)

3D structure

• AlphaFold DB: A0A2T3RS91

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Escherichia coli BW25113 strain K-12	90.431	100	0.904