Detailed information NTG0702100

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: NIZ24_RS14125
• Genome accession: NZ_CP099871
• Coordinates: 2890800..2891429 (-)
• Length: 209 a.a.
• NCBI ID: WP_000839162.1
• Uniprot ID: A0A2T3RS91
• Organism: Escherichia albertii strain 253_2_EW_B
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
ICE	2876891..2891229	2890800..2891429	flank	-429

Gene organization within MGE regions

Location: 2876891..2891429

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NIZ24_RS14055 (NIZ24_14055)	-	2876954..2879434 (+)	2481	WP_256877922.1	exonuclease	-
NIZ24_RS14060 (NIZ24_14060)	-	2879501..2879752 (+)	252	WP_059278349.1	DUF4224 domain-containing protein	-
NIZ24_RS14065 (NIZ24_14065)	-	2879721..2880740 (+)	1020	WP_001372523.1	tyrosine-type recombinase/integrase	-
NIZ24_RS14070 (NIZ24_14070)	yccA	2881149..2881808 (+)	660	WP_000375136.1	FtsH protease modulator YccA	-
NIZ24_RS14075 (NIZ24_14075)	tusE	2881900..2882229 (+)	330	WP_059251577.1	sulfurtransferase TusE	-
NIZ24_RS14080 (NIZ24_14080)	yccX	2882226..2882504 (-)	279	WP_000048219.1	acylphosphatase	-
NIZ24_RS14085 (NIZ24_14085)	rlmI	2882598..2883788 (+)	1191	WP_059251552.1	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	-
NIZ24_RS14090 (NIZ24_14090)	hspQ	2883846..2884163 (+)	318	WP_001295356.1	heat shock protein HspQ	-
NIZ24_RS14095 (NIZ24_14095)	-	2884208..2884621 (-)	414	WP_002462360.1	CoA-binding protein	-
NIZ24_RS14100 (NIZ24_14100)	-	2884794..2885456 (+)	663	WP_000847777.1	DUF2057 family protein	-
NIZ24_RS14105 (NIZ24_14105)	mgsA	2885552..2886010 (+)	459	WP_000424182.1	methylglyoxal synthase	-
NIZ24_RS14110 (NIZ24_14110)	helD	2886042..2888096 (-)	2055	WP_000420534.1	DNA helicase IV	-
NIZ24_RS14115 (NIZ24_14115)	-	2888219..2888665 (+)	447	WP_001261228.1	YccF domain-containing protein	-
NIZ24_RS14120 (NIZ24_14120)	yccS	2888675..2890840 (+)	2166	WP_072244615.1	YccS family putative transporter	-
NIZ24_RS14125 (NIZ24_14125)	sxy/tfoX	2890800..2891429 (-)	630	WP_000839162.1	TfoX/Sxy family DNA transformation protein	Regulator

Sequence

Protein

• Length: 209 a.a.
• Molecular weight: 24291.21 Da
• Isoelectric Point: 9.0264

>NTDB_id=702100 NIZ24_RS14125 WP_000839162.1 2890800..2891429(-) (sxy/tfoX) [Escherichia albertii strain 253_2_EW_B]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVNDTVFAMVADGELYLRACEQSVQYCVKHPPVWLTYKKCGRPVTLN
YYRVDESLWRNQQKLVRLSKYSLDAALKEKCTRNNLQRLKDLPNMSYHLEAILGEVGIKDVRTLRILGAKMCWLRLRQHN
SQVTEKILFMLEGAIIDIHEAALPVARRQELAEWAESIVPKPEFPTEPE

Nucleotide

• Length: 630 bp

>NTDB_id=702100 NIZ24_RS14125 WP_000839162.1 2890800..2891429(-) (sxy/tfoX) [Escherichia albertii strain 253_2_EW_B]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAGTCACAAGAATACCTTGCAACGTTAGGCACCATTGAATATCGATCGCT
GTTTGGCAGTTACAGTTTGACGGTTAACGATACGGTATTTGCGATGGTTGCTGATGGTGAGTTGTATCTACGGGCTTGTG
AACAAAGCGTACAGTACTGTGTAAAACATCCGCCAGTCTGGCTGACATATAAAAAGTGCGGCCGACCCGTGACTCTCAAT
TACTACCGGGTTGATGAAAGTCTATGGCGTAACCAACAGAAATTAGTTCGCTTGTCGAAATATTCCCTGGATGCTGCGCT
GAAAGAGAAATGTACGCGCAACAATCTCCAGCGACTGAAAGATTTGCCGAATATGTCTTATCACCTGGAGGCGATTCTCG
GTGAAGTGGGGATCAAGGATGTGCGGACTTTACGGATCCTTGGCGCAAAAATGTGCTGGTTGCGACTACGTCAGCATAAT
AGCCAGGTGACGGAGAAGATCTTATTCATGCTTGAAGGCGCAATTATTGATATTCATGAAGCAGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCTGAATGGGCTGAATCTATTGTGCCGAAACCGGAGTTTCCGACGGAACCTGAGTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (117-194)

• TfoX N-terminal domain (TfoX_N) (14-106)

3D structure

• AlphaFold DB: A0A2T3RS91

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Escherichia coli BW25113 strain K-12	90.431	100	0.904