Detailed information NTG0700803

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: NHB12_RS13980
• Genome accession: NZ_CP099576
• Coordinates: 2774252..2775139 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain MRSA1369
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2769252..2780139

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NHB12_RS13950 (NHB12_13950)	-	2769271..2769363 (+)	93	WP_010956583.1	hypothetical protein	-
NHB12_RS13955 (NHB12_13955)	-	2769471..2769968 (-)	498	WP_001065268.1	glutathione peroxidase	-
NHB12_RS13960 (NHB12_13960)	-	2769978..2770238 (-)	261	WP_001789910.1	hypothetical protein	-
NHB12_RS13965 (NHB12_13965)	-	2770620..2770733 (-)	114	WP_001791776.1	hypothetical protein	-
NHB12_RS13970 (NHB12_13970)	-	2771392..2773392 (-)	2001	WP_000776751.1	ABC transporter permease	-
NHB12_RS13975 (NHB12_13975)	-	2773389..2774144 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
NHB12_RS13980 (NHB12_13980)	braS	2774252..2775139 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
NHB12_RS13985 (NHB12_13985)	braR	2775150..2775815 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
NHB12_RS13990 (NHB12_13990)	-	2775841..2776041 (-)	201	WP_000604728.1	hypothetical protein	-
NHB12_RS13995 (NHB12_13995)	-	2776239..2777663 (+)	1425	WP_000953744.1	alkaline phosphatase	-
NHB12_RS14625	-	2777723..2777824 (-)	102	WP_000731972.1	SE2200 family small protein	-
NHB12_RS14005 (NHB12_14005)	-	2777946..2778401 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
NHB12_RS14010 (NHB12_14010)	-	2778646..2779407 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=700803 NHB12_RS13980 WP_000143419.1 2774252..2775139(-) (braS) [Staphylococcus aureus strain MRSA1369]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=700803 NHB12_RS13980 WP_000143419.1 2774252..2775139(-) (braS) [Staphylococcus aureus strain MRSA1369]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997