Detailed information NTG0070047

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: HPTL_RS08395
• Genome accession: NZ_AP018558
• Coordinates: 1722759..1723670 (-)
• Length: 303 a.a.
• NCBI ID: WP_119335583.1
• Uniprot ID: A0A2Z6DZA1
• Organism: Hydrogenophilus thermoluteolus strain TH-1
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1717759..1728670

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPTL_RS11490	-	1718808..1719861 (+)	1054	Protein_1629	AAA family ATPase	-
HPTL_RS08375	-	1719988..1720740 (+)	753	WP_119335579.1	M48 family metallopeptidase	-
HPTL_RS08380 (HPTL_1623)	crcB	1720763..1721155 (-)	393	WP_119335580.1	fluoride efflux transporter CrcB	-
HPTL_RS08385 (HPTL_1624)	-	1721184..1722080 (-)	897	WP_119335581.1	hypothetical protein	-
HPTL_RS08390 (HPTL_1625)	-	1722077..1722745 (-)	669	WP_119335582.1	cell division ATP-binding protein FtsE	-
HPTL_RS08395 (HPTL_1626)	pilA	1722759..1723670 (-)	912	WP_119335583.1	signal recognition particle-docking protein FtsY	Machinery gene
HPTL_RS08400 (HPTL_1627)	-	1723767..1725164 (+)	1398	WP_119335584.1	pitrilysin family protein	-
HPTL_RS08405 (HPTL_1628)	-	1725161..1726582 (+)	1422	WP_119335585.1	pitrilysin family protein	-
HPTL_RS08410 (HPTL_1629)	rsmD	1726604..1727164 (+)	561	WP_119335586.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
HPTL_RS08415 (HPTL_1630)	coaD	1727151..1727639 (+)	489	WP_119335587.1	pantetheine-phosphate adenylyltransferase	-
HPTL_RS08420 (HPTL_1631)	-	1727669..1727920 (+)	252	WP_119335588.1	YfhL family 4Fe-4S dicluster ferredoxin	-
HPTL_RS08425 (HPTL_1632)	-	1727938..1728420 (-)	483	WP_119335589.1	CreA family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 32788.14 Da
• Isoelectric Point: 7.3635

>NTDB_id=70047 HPTL_RS08395 WP_119335583.1 1722759..1723670(-) (pilA) [Hydrogenophilus thermoluteolus strain TH-1]
MFSWLHRLKAGLSRTRGQLVSLFTGRKIDEAFLEELETTLLMADCGIEVTETLMARIRERIKRDRLEAAESLRQVLADEL
ETLLAPLEAPLDVSVAHPFVIMVAGVNGAGKTTSIGKLARWYQAQGKKVMLAAGDTFRAAAREQLVIWGERNGVPVIAQE
KGDPAAVAFDAVQAAKARGYDVLIVDTAGRLPTQLHLMEEIAKVRRVIQKAEPSAPHEVLLVLDANIGQNAIAQAEAFDK
AIGVTGFILTKLDGTAKGGVIAALAKRLPKPVRFVGVGEGVDDLRPFVARDFVAALVGLERLE

Nucleotide

• Length: 912 bp

>NTDB_id=70047 HPTL_RS08395 WP_119335583.1 1722759..1723670(-) (pilA) [Hydrogenophilus thermoluteolus strain TH-1]
ATGTTCAGTTGGTTGCACCGCCTCAAAGCGGGCTTGTCGCGCACCCGCGGGCAATTGGTTTCGCTCTTTACCGGGCGCAA
GATCGACGAAGCGTTCCTGGAAGAGCTCGAAACCACCCTGCTGATGGCCGATTGCGGTATCGAGGTGACCGAAACCCTGA
TGGCGCGGATCCGTGAGCGGATCAAGCGGGACCGGCTGGAAGCGGCCGAATCGCTGCGTCAGGTGCTGGCCGACGAGCTC
GAAACGTTGTTGGCGCCTTTGGAAGCGCCGCTCGACGTCAGCGTCGCGCACCCCTTCGTGATCATGGTGGCGGGCGTAAA
TGGCGCCGGCAAGACGACCTCGATCGGGAAACTCGCCCGTTGGTACCAAGCGCAAGGCAAGAAGGTGATGCTGGCTGCGG
GCGACACGTTTCGTGCCGCGGCGCGCGAACAGTTGGTGATCTGGGGCGAACGTAACGGCGTGCCGGTGATCGCGCAAGAG
AAGGGTGACCCCGCCGCGGTGGCGTTCGATGCGGTGCAGGCCGCGAAAGCGCGCGGCTATGACGTGCTCATCGTCGATAC
CGCGGGGCGCTTGCCCACGCAACTCCACCTCATGGAAGAGATCGCCAAGGTGCGACGGGTGATTCAAAAAGCGGAACCCA
GCGCGCCGCACGAAGTGCTGCTGGTGCTCGATGCCAATATCGGTCAAAACGCGATCGCGCAGGCCGAAGCGTTCGACAAA
GCGATCGGCGTCACCGGTTTCATTCTCACCAAGCTCGACGGCACCGCAAAAGGAGGTGTGATTGCGGCGCTTGCGAAACG
GTTGCCGAAACCGGTTCGTTTCGTCGGTGTCGGCGAAGGGGTAGATGACCTTCGGCCGTTTGTCGCGCGCGACTTCGTCG
CCGCGCTGGTGGGCTTAGAACGCTTGGAATGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (98-297)

• SRP54-type protein, helical bundle domain (SRP54_N) (20-80)

3D structure

• AlphaFold DB: A0A2Z6DZA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	61.794	99.34	0.614