Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LPT22_RS08485 Genome accession   NZ_CP099506
Coordinates   1694056..1694772 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 0316-H-5A     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1689056..1699772
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPT22_RS08455 (LPT22_08455) - 1689323..1689949 (+) 627 WP_000522384.1 nitroreductase family protein -
  LPT22_RS08460 (LPT22_08460) - 1690257..1691042 (+) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  LPT22_RS08465 (LPT22_08465) hld 1691644..1691724 (-) 81 WP_000046022.1 delta-hemolysin -
  LPT22_RS08470 (LPT22_08470) agrB 1692014..1692583 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  LPT22_RS08475 (LPT22_08475) - 1692580..1692720 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide -
  LPT22_RS08480 (LPT22_08480) - 1692745..1694037 (+) 1293 WP_001825886.1 GHKL domain-containing protein -
  LPT22_RS08485 (LPT22_08485) agrA 1694056..1694772 (+) 717 WP_000688492.1 LytTR family DNA-binding domain-containing protein Regulator
  LPT22_RS08490 (LPT22_08490) - 1695146..1696105 (-) 960 WP_001253294.1 carbohydrate kinase -
  LPT22_RS08495 (LPT22_08495) - 1696102..1697586 (-) 1485 WP_229360499.1 sucrose-6-phosphate hydrolase -
  LPT22_RS08500 (LPT22_08500) - 1697735..1698685 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=700251 LPT22_RS08485 WP_000688492.1 1694056..1694772(+) (agrA) [Staphylococcus aureus strain 0316-H-5A]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=700251 LPT22_RS08485 WP_000688492.1 1694056..1694772(+) (agrA) [Staphylococcus aureus strain 0316-H-5A]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1