Detailed information NTG0700250

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LPT22_RS08055
• Genome accession: NZ_CP099506
• Coordinates: 1608052..1609095 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 0316-H-5A
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1603052..1614095

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPT22_RS08025 (LPT22_08025)	-	1603473..1604729 (-)	1257	WP_001793428.1	aminopeptidase	-
LPT22_RS08030 (LPT22_08030)	-	1604732..1604932 (-)	201	WP_000180460.1	DUF1128 family protein	-
LPT22_RS08035 (LPT22_08035)	-	1605079..1605543 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
LPT22_RS08040 (LPT22_08040)	-	1605550..1605825 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
LPT22_RS08045 (LPT22_08045)	-	1606103..1607320 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
LPT22_RS08050 (LPT22_08050)	vraR	1607433..1608062 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
LPT22_RS08055 (LPT22_08055)	vraS	1608052..1609095 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
LPT22_RS08060 (LPT22_08060)	liaF	1609092..1609793 (-)	702	WP_031886362.1	cell wall-active antibiotics response protein LiaF	-
LPT22_RS08065 (LPT22_08065)	-	1609808..1610194 (-)	387	WP_001110182.1	hypothetical protein	-
LPT22_RS08070 (LPT22_08070)	map	1610411..1611169 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
LPT22_RS08075 (LPT22_08075)	-	1611753..1612739 (+)	987	WP_000999712.1	aromatic acid exporter family protein	-
LPT22_RS08080 (LPT22_08080)	-	1612928..1613341 (-)	414	WP_025174370.1	hypothetical protein	-
LPT22_RS08085 (LPT22_08085)	-	1613370..1613480 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=700250 LPT22_RS08055 WP_001017131.1 1608052..1609095(-) (vraS) [Staphylococcus aureus strain 0316-H-5A]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=700250 LPT22_RS08055 WP_001017131.1 1608052..1609095(-) (vraS) [Staphylococcus aureus strain 0316-H-5A]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1