Detailed information NTG0700198

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LPT20_RS11585
• Genome accession: NZ_CP099504
• Coordinates: 2402663..2403706 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain S36
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2397663..2408706

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPT20_RS11555 (LPT20_11555)	-	2398088..2398199 (+)	112	Protein_2276	hypothetical protein	-
LPT20_RS11560 (LPT20_11560)	-	2398228..2398641 (+)	414	WP_025174552.1	hypothetical protein	-
LPT20_RS11565 (LPT20_11565)	-	2399074..2400060 (-)	987	WP_000999708.1	aromatic acid exporter family protein	-
LPT20_RS11570 (LPT20_11570)	map	2400589..2401347 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
LPT20_RS11575 (LPT20_11575)	-	2401564..2401950 (+)	387	WP_001110179.1	hypothetical protein	-
LPT20_RS11580 (LPT20_11580)	liaF	2401965..2402666 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
LPT20_RS11585 (LPT20_11585)	vraS	2402663..2403706 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
LPT20_RS11590 (LPT20_11590)	vraR	2403696..2404325 (+)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
LPT20_RS11595 (LPT20_11595)	-	2404438..2405655 (-)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
LPT20_RS11600 (LPT20_11600)	-	2405933..2406208 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
LPT20_RS11605 (LPT20_11605)	-	2406215..2406679 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
LPT20_RS11610 (LPT20_11610)	-	2406826..2407026 (+)	201	WP_000180460.1	DUF1128 family protein	-
LPT20_RS11615 (LPT20_11615)	-	2407029..2408285 (+)	1257	WP_078065149.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=700198 LPT20_RS11585 WP_001017131.1 2402663..2403706(+) (vraS) [Staphylococcus aureus strain S36]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=700198 LPT20_RS11585 WP_001017131.1 2402663..2403706(+) (vraS) [Staphylococcus aureus strain S36]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1