Detailed information NTG0700079

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LPT21_RS07720
• Genome accession: NZ_CP099497
• Coordinates: 1572499..1573542 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 0213-M-4A
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1567499..1578542

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPT21_RS07690 (LPT21_07690)	-	1567920..1569176 (-)	1257	WP_001793428.1	aminopeptidase	-
LPT21_RS07695 (LPT21_07695)	-	1569179..1569379 (-)	201	WP_000180460.1	DUF1128 family protein	-
LPT21_RS07700 (LPT21_07700)	-	1569526..1569990 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
LPT21_RS07705 (LPT21_07705)	-	1569997..1570272 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
LPT21_RS07710 (LPT21_07710)	-	1570550..1571767 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
LPT21_RS07715 (LPT21_07715)	vraR	1571880..1572509 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
LPT21_RS07720 (LPT21_07720)	vraS	1572499..1573542 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
LPT21_RS07725 (LPT21_07725)	liaF	1573539..1574240 (-)	702	WP_031886362.1	cell wall-active antibiotics response protein LiaF	-
LPT21_RS07730 (LPT21_07730)	-	1574255..1574641 (-)	387	WP_001110182.1	hypothetical protein	-
LPT21_RS07735 (LPT21_07735)	map	1574858..1575616 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
LPT21_RS07740 (LPT21_07740)	-	1576200..1577186 (+)	987	WP_000999712.1	aromatic acid exporter family protein	-
LPT21_RS07745 (LPT21_07745)	-	1577375..1577788 (-)	414	WP_025174370.1	hypothetical protein	-
LPT21_RS07750 (LPT21_07750)	-	1577817..1577927 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=700079 LPT21_RS07720 WP_001017131.1 1572499..1573542(-) (vraS) [Staphylococcus aureus strain 0213-M-4A]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=700079 LPT21_RS07720 WP_001017131.1 1572499..1573542(-) (vraS) [Staphylococcus aureus strain 0213-M-4A]
ATGAATCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1