Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   NF323_RS00435 Genome accession   NZ_CP098820
Coordinates   100799..102427 (+) Length   542 a.a.
NCBI ID   WP_001186596.1    Uniprot ID   -
Organism   Staphylococcus capitis strain XWZ     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 99432..120920 100799..102427 within 0


Gene organization within MGE regions


Location: 99432..120920
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NF323_RS00430 (NF323_00430) ccrA 99432..100778 (+) 1347 WP_000816499.1 recombinase family protein Machinery gene
  NF323_RS00435 (NF323_00435) ccrB 100799..102427 (+) 1629 WP_001186596.1 recombinase family protein Machinery gene
  NF323_RS00440 (NF323_00440) - 102898..103248 (+) 351 WP_000171449.1 SAUGI family uracil-DNA glycosylase inhibitor -
  NF323_RS00445 (NF323_00445) - 103333..103644 (+) 312 WP_000833212.1 DUF960 family protein -
  NF323_RS00450 (NF323_00450) - 103663..104184 (+) 522 WP_000836008.1 DUF1643 domain-containing protein -
  NF323_RS00455 (NF323_00455) - 104186..104392 (+) 207 WP_001077283.1 hypothetical protein -
  NF323_RS00460 (NF323_00460) - 104385..104708 (+) 324 WP_030063452.1 JAB domain-containing protein -
  NF323_RS00465 (NF323_00465) - 104827..105912 (+) 1086 WP_000868132.1 tyrosine-type recombinase/integrase -
  NF323_RS00470 (NF323_00470) - 105909..107801 (+) 1893 WP_001557544.1 site-specific integrase -
  NF323_RS00475 (NF323_00475) - 107808..108185 (+) 378 WP_000361059.1 DUF6262 family protein -
  NF323_RS00480 (NF323_00480) - 108336..109118 (+) 783 WP_000067268.1 aminoglycoside nucleotidyltransferase ANT(9)-Ia -
  NF323_RS00485 (NF323_00485) erm(A) 109244..109975 (-) 732 WP_001072201.1 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) -
  NF323_RS00490 (NF323_00490) - 110484..111146 (+) 663 WP_001092058.1 class I SAM-dependent methyltransferase -
  NF323_RS00495 (NF323_00495) - 111491..112129 (-) 639 Protein_96 sulfite exporter TauE/SafE family protein -
  NF323_RS00500 (NF323_00500) cstR 112129..112389 (-) 261 WP_000220507.1 persulfide-sensing transcriptional repressor CstR -
  NF323_RS00505 (NF323_00505) - 112525..113589 (+) 1065 WP_000438836.1 DsrE/DsrF/DrsH-like family protein -
  NF323_RS00510 (NF323_00510) cstB 113622..114956 (+) 1335 Protein_99 persulfide dioxygenase-sulfurtransferase CstB -
  NF323_RS00515 (NF323_00515) - 115070..116200 (-) 1131 WP_010922808.1 ROK family transcriptional regulator -
  NF323_RS00520 (NF323_00520) psm-mec 116533..116601 (+) 69 WP_014532405.1 phenol-soluble modulin PSM-mec -
  NF323_RS00525 (NF323_00525) mecI 116686..117057 (-) 372 WP_000369214.1 mecA-type methicillin resistance repressor MecI -
  NF323_RS00530 (NF323_00530) mecR1 117057..118814 (-) 1758 WP_000952923.1 beta-lactam sensor/signal transducer MecR1 -
  NF323_RS00535 (NF323_00535) mecA 118911..120920 (+) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62274.15 Da        Isoelectric Point: 9.7334

>NTDB_id=698170 NF323_RS00435 WP_001186596.1 100799..102427(+) (ccrB) [Staphylococcus capitis strain XWZ]
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=698170 NF323_RS00435 WP_001186596.1 100799..102427(+) (ccrB) [Staphylococcus capitis strain XWZ]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAGAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(11-156)

Recombinase (Recombinase)

(180-280)

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

86.531

100

0.865