Detailed information NTG0069814

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LLCC_RS12380
• Genome accession: NZ_AP018499
• Coordinates: 2392591..2394837 (-)
• Length: 748 a.a.
• NCBI ID: WP_011675568.1
• Uniprot ID: -
• Organism: Lactococcus cremoris strain C4
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2387591..2399837

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLCC_RS12360 (LLCC_2628)	-	2389338..2389742 (-)	405	WP_011675572.1	RNA pyrophosphohydrolase	-
LLCC_RS12365 (LLCC_2629)	def	2389897..2390532 (+)	636	WP_061778059.1	peptide deformylase	-
LLCC_RS12370 (LLCC_2630)	gap	2390756..2391769 (-)	1014	WP_061778060.1	type I glyceraldehyde-3-phosphate dehydrogenase	-
LLCC_RS12375 (LLCC_2631)	-	2391995..2392465 (+)	471	WP_011675569.1	Rrf2 family transcriptional regulator	-
LLCC_RS12380 (LLCC_2632)	clpC	2392591..2394837 (-)	2247	WP_011675568.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
LLCC_RS12385 (LLCC_2633)	-	2394883..2395227 (-)	345	WP_011834562.1	hypothetical protein	-
LLCC_RS14455 (LLCC_2634)	-	2395456..2396106 (-)	651	WP_232035061.1	hypothetical protein	-
LLCC_RS14460 (LLCC_2635)	-	2396103..2396636 (-)	534	WP_232035062.1	hypothetical protein	-
LLCC_RS14720 (LLCC_2636)	-	2396729..2396998 (-)	270	WP_031299006.1	DUF6574 domain-containing protein	-
LLCC_RS14470 (LLCC_2637)	-	2397146..2397511 (-)	366	WP_232035063.1	DUF6574 domain-containing protein	-
LLCC_RS14475	-	2397538..2397594 (-)	57	Protein_2436	hypothetical protein	-
LLCC_RS12400 (LLCC_2639)	-	2397749..2397949 (-)	201	WP_126355074.1	hypothetical protein	-
LLCC_RS12405 (LLCC_2640)	-	2397916..2398101 (-)	186	WP_164717661.1	MFS transporter	-
LLCC_RS12410 (LLCC_2641)	-	2398124..2399122 (-)	999	WP_126355079.1	MFS transporter	-
LLCC_RS14480	-	2399351..2399518 (-)	168	WP_232035064.1	hypothetical protein	-

Sequence

Protein

• Length: 748 a.a.
• Molecular weight: 83194.00 Da
• Isoelectric Point: 4.7590

>NTDB_id=69814 LLCC_RS12380 WP_011675568.1 2392591..2394837(-) (clpC) [Lactococcus cremoris strain C4]
MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALQGQDFNGAASN
QTPPTQTGGRGPRGPQNPRAKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTA
VVEGLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMD
AGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAH
LSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAESKKNEATKAEDFEKAAHFRDQISKLRELQKQEVT
DEDMPVITEKDIEQIVEQKTQIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKISKAIRRSRVGLGKPNRPIGSFLFV
GPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHP
DVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKVEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEF
SALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRTIQENIEDSIADFYIEHPEYKQLV
ADLIDDKIVISNQTQETAETTDEEVPAE

Nucleotide

• Length: 2247 bp

>NTDB_id=69814 LLCC_RS12380 WP_011675568.1 2392591..2394837(-) (clpC) [Lactococcus cremoris strain C4]
ATGCTTTGTCAAAATTGTAATATTAATGAAGCGACGATTCACCTTTACACAAGTGTAAATGGTCAGAAAAAACAAATTGA
TTTGTGCCAAAACTGTTATCAAATTATGAAATCTGGTGGTCAAGAAGCTTTATTTGGCGCAGGAAATGCCTCAAATGGAA
ATTCTGATGAACCCTTTAATCCGTTTAACGATATCTTCAGTGCTTTGCAAGGTCAAGATTTTAATGGGGCAGCAAGTAAT
CAAACTCCCCCAACACAAACGGGTGGGCGTGGTCCGCGTGGTCCACAAAATCCTCGGGCAAAACAACCTAAAGGGATGCT
AGAAGAATTCGGTATTAATATCACCGAATCAGCTCGTCGTGGCGAAATTGACCCAGTGATTGGGCGTGATGAAGAAATCA
AACGTGTTATTGAGATTTTAAATCGCAGAACTAAGAATAATCCAGTGCTAATTGGTGAACCTGGTGTTGGTAAAACAGCA
GTTGTTGAAGGTTTAGCACAAAAAATAGTCGATGGCGATGTGCCACAAAAACTGCAAAATAAAGAAGTTATTCGTCTTGA
CGTGGTTTCTCTTGTTCAAGGAACAGGAATTCGTGGACAATTTGAAGAACGGATGCAAAAATTAATGGATGAAATCAGAA
AACGTAATGATGTCATTATGTTTATTGATGAAATTCATGAAATTGTCGGTGCTGGTTCTGCTGGCGACGGCAATATGGAT
GCAGGTAATATCCTAAAACCGGCTCTTGCACGTGGTGAGCTTCAATTGGTTGGAGCAACAACACTCAACGAATATCGTAT
TATTGAAAAAGATGCGGCACTTGAACGTCGGATGCAACCGGTCAAAGTAGATGAACCATCAGTTGATGAAACAATTACGA
TTTTGCGAGGCATTCAAGCACGTTATGAAGATTATCATCATGTGAAATACACTGATGAGGCTATTGAAGCAGCTGCTCAT
TTGTCAAATCGTTACATTCAAGACCGATTCTTACCAGATAAAGCCATCGACCTTTTAGATGAATCTGGTTCTAAGAAAAA
TCTGACTTTGAAATTTGTTGACCCTGAGGATATCAATCGTCGAATTGCTGATGCGGAAAGTAAGAAAAATGAAGCAACTA
AGGCTGAAGATTTTGAAAAAGCCGCTCATTTCCGTGACCAAATCAGTAAACTTCGTGAATTGCAAAAACAAGAAGTTACT
GACGAAGATATGCCAGTCATCACTGAAAAAGATATTGAACAAATTGTTGAACAAAAAACACAAATTCCAGTTGGGGATTT
GAAAGAAAAAGAACAAACTCAGTTGATTAATTTGGCTGATGATTTGAAAGCACATGTGATTGGTCAAGATGAAGCAGTAG
ATAAAATATCAAAAGCAATTCGTCGCTCACGTGTAGGTCTTGGCAAACCTAACCGTCCAATTGGTTCTTTCCTTTTTGTT
GGTCCAACAGGTGTAGGTAAAACCGAACTTGCTAAACAATTGGCTAAAGAATTATTTGGCTCAAGTGAGAGCATGATTCG
TTTTGATATGTCGGAATACATGGAAAAACATTCGGTGGCCAAATTGATTGGTGCGCCTCCAGGATATGTAGGTTATGAAG
AAGCGGGTCAATTGACCGAACGTGTTCGTCGTAATCCATACAGTTTGATTTTGCTTGATGAAATTGAAAAAGCTCATCCT
GATGTCATGCACATGTTCTTACAAATTCTTGAAGATGGCCGTCTGACAGATGCACAAGGACGGACAGTATCCTTCAAAGA
TAGTTTGATTATCATGACTTCAAATGCCGGAACTGGTAAAGTTGAAGCTTCTGTTGGATTTGGTGCAGCCCGCGAAGGAC
GAACTAAATCAGTGCTTGGTCAACTTGGTGATTTCTTTAGCCCTGAATTCATGAACCGTTTTGACGGAATTATTGAATTC
TCTGCTTTAAGCAAAGAAAATCTCCTTAAAATTGTTGATTTAATGCTTGATGAAGTCAATGAACAAATTGGACGTAATGA
TATTCATCTTAGTGTCACTCAAGCCGCTAAAGAAAAATTAGTGGACTTAGGATATAACCCTGCAATGGGTGCAAGACCTC
TTCGTAGAACAATTCAAGAAAATATTGAAGATTCAATTGCTGATTTCTACATTGAACATCCTGAATATAAACAATTGGTA
GCTGATTTGATTGATGATAAAATTGTCATTTCTAATCAAACCCAAGAAACAGCAGAAACCACTGATGAAGAAGTTCCTGC
CGAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (287-386)

• AAA domain (Cdc48 subfamily) (AAA_2) (472-635)

• ATPase family associated with various cellular activities (AAA) (AAA) (149-268)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (643-713)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	99.866	100	0.999
clpE	Streptococcus mutans UA159	75.894	100	0.766
clpE	Streptococcus pneumoniae Rx1	75.815	98.396	0.746
clpE	Streptococcus pneumoniae D39	75.815	98.396	0.746
clpE	Streptococcus pneumoniae R6	75.815	98.396	0.746
clpE	Streptococcus pneumoniae TIGR4	75.815	98.396	0.746
clpC	Bacillus subtilis subsp. subtilis str. 168	48.664	95.053	0.463
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.023	87.567	0.412
clpC	Streptococcus pneumoniae Rx1	46.955	83.422	0.392
clpC	Streptococcus pneumoniae D39	46.955	83.422	0.392
clpC	Streptococcus pneumoniae TIGR4	46.955	83.422	0.392
clpC	Streptococcus thermophilus LMD-9	46.429	82.353	0.382
clpC	Streptococcus thermophilus LMG 18311	46.266	82.353	0.381
clpC	Streptococcus mutans UA159	45.631	82.62	0.377