Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   M5C73_RS11840 Genome accession   NZ_CP098790
Coordinates   2379453..2380481 (-) Length   342 a.a.
NCBI ID   WP_003132657.1    Uniprot ID   S6FVM6
Organism   Lactococcus lactis strain WiKim0124     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 2374453..2385481
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5C73_RS11815 (M5C73_11815) - 2374498..2375343 (-) 846 WP_252160132.1 radical SAM protein -
  M5C73_RS11820 (M5C73_11820) - 2375527..2376384 (-) 858 WP_252160133.1 Rgg/GadR/MutR family transcriptional regulator -
  M5C73_RS11825 (M5C73_11825) - 2376495..2377634 (-) 1140 WP_012898644.1 MFS transporter -
  M5C73_RS11830 (M5C73_11830) kwcM 2377631..2378950 (-) 1320 WP_129881186.1 KxxxW cyclic peptide radical SAM maturase -
  M5C73_RS11835 (M5C73_11835) - 2379018..2379131 (-) 114 WP_011836076.1 KxxxW-cyclized peptide pheromone -
  M5C73_RS11840 (M5C73_11840) sepM 2379453..2380481 (-) 1029 WP_003132657.1 SepM family pheromone-processing serine protease Regulator
  M5C73_RS11845 (M5C73_11845) coaD 2380468..2380965 (-) 498 WP_010906348.1 pantetheine-phosphate adenylyltransferase -
  M5C73_RS11850 (M5C73_11850) rsmD 2381012..2381551 (-) 540 WP_015427191.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  M5C73_RS11855 (M5C73_11855) - 2381722..2382942 (-) 1221 WP_252160134.1 MFS transporter -
  M5C73_RS11860 (M5C73_11860) lmrP 2383023..2384249 (-) 1227 WP_129881188.1 multidrug efflux MFS transporter LmrP -

Sequence

Protein


Download         Length: 342 a.a.        Molecular weight: 37349.96 Da        Isoelectric Point: 9.9183

>NTDB_id=698000 M5C73_RS11840 WP_003132657.1 2379453..2380481(-) (sepM) [Lactococcus lactis strain WiKim0124]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1029 bp        

>NTDB_id=698000 M5C73_RS11840 WP_003132657.1 2379453..2380481(-) (sepM) [Lactococcus lactis strain WiKim0124]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTACCCAACAAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGAAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTTCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGCGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(134-194)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(227-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FVM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.696

100

0.491