Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   M5C73_RS08255 Genome accession   NZ_CP098790
Coordinates   1708212..1709687 (-) Length   491 a.a.
NCBI ID   WP_252159996.1    Uniprot ID   -
Organism   Lactococcus lactis strain WiKim0124     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1703212..1714687
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5C73_RS08240 (M5C73_08240) murD 1704471..1705823 (-) 1353 WP_003130748.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  M5C73_RS08245 (M5C73_08245) - 1706315..1706656 (-) 342 WP_010906046.1 P-II family nitrogen regulator -
  M5C73_RS08250 (M5C73_08250) - 1706788..1708029 (-) 1242 WP_168784474.1 ammonium transporter -
  M5C73_RS08255 (M5C73_08255) covS 1708212..1709687 (-) 1476 WP_252159996.1 HAMP domain-containing histidine kinase Regulator
  M5C73_RS08260 (M5C73_08260) covR 1709696..1710388 (-) 693 WP_003130756.1 response regulator transcription factor Regulator
  M5C73_RS08265 (M5C73_08265) - 1710544..1711074 (-) 531 WP_058212571.1 DUF177 domain-containing protein -
  M5C73_RS08270 (M5C73_08270) - 1711205..1711450 (-) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  M5C73_RS08275 (M5C73_08275) - 1711606..1712070 (-) 465 WP_017864799.1 hypothetical protein -
  M5C73_RS08280 (M5C73_08280) - 1712152..1712514 (-) 363 WP_010906050.1 TIGR02328 family protein -
  M5C73_RS08285 (M5C73_08285) - 1712998..1713528 (-) 531 WP_058211263.1 CHAP domain-containing protein -
  M5C73_RS08290 (M5C73_08290) - 1713590..1714426 (-) 837 WP_058211264.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 491 a.a.        Molecular weight: 56225.06 Da        Isoelectric Point: 4.7862

>NTDB_id=697973 M5C73_RS08255 WP_252159996.1 1708212..1709687(-) (covS) [Lactococcus lactis strain WiKim0124]
MKKLFTFNKKKETEEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGISEEDINHLFERFFRADKARNREIGGTGLGLSILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide


Download         Length: 1476 bp        

>NTDB_id=697973 M5C73_RS08255 WP_252159996.1 1708212..1709687(-) (covS) [Lactococcus lactis strain WiKim0124]
ATGAAAAAATTATTTACTTTCAATAAGAAAAAAGAGACGGAAGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATAAGTTCTT
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGGACACGGAAAGCATTTTATATTTATGACTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAAAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTGTCGCTCAGTTGATTGGTTATTTCATGGCTAATTACTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCATGTTTACAATGATATGATGTTGAAGATGAAGGCATATCTTGAACAGCA
AAATCGCTTTGTTTCTGATGTTTCTCATGAATTAAGAACACCTTTAGCTGTCTTGGATGGACATATTAACTTGTTGAATC
GATGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGCCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGTTTACGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGTGATTACTGTTTCTGAGGATGAACAGTTTGTCATTACGAGTGTATCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTAATCATCTTTTTGAGCGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTATCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

ArlS sensor domain (ArlS_N)

(54-185)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-489)

HAMP domain (HAMP)

(208-258)

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

99.796

100

0.998