Detailed information NTG0697963

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: M5C73_RS02660
• Genome accession: NZ_CP098790
• Coordinates: 520096..522342 (+)
• Length: 748 a.a.
• NCBI ID: WP_098383584.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain WiKim0124
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 515096..527342

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M5C73_RS02640 (M5C73_02640)	rpoD	515691..517034 (+)	1344	WP_003130829.1	RNA polymerase sigma factor RpoD	-
M5C73_RS02645 (M5C73_02645)	-	517149..517892 (+)	744	WP_010905438.1	MurR/RpiR family transcriptional regulator	-
M5C73_RS02650 (M5C73_02650)	-	518057..519424 (+)	1368	WP_165379815.1	MFS transporter	-
M5C73_RS02655 (M5C73_02655)	-	519707..520045 (+)	339	WP_021723450.1	hypothetical protein	-
M5C73_RS02660 (M5C73_02660)	clpC	520096..522342 (+)	2247	WP_098383584.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
M5C73_RS02665 (M5C73_02665)	-	522633..523103 (-)	471	WP_003130820.1	Rrf2 family transcriptional regulator	-
M5C73_RS02670 (M5C73_02670)	gap	523276..524289 (+)	1014	WP_003130818.1	type I glyceraldehyde-3-phosphate dehydrogenase	-
M5C73_RS02675 (M5C73_02675)	def	524432..525067 (-)	636	WP_003130816.1	peptide deformylase	-
M5C73_RS02680 (M5C73_02680)	-	525215..525676 (+)	462	WP_306171264.1	RNA pyrophosphohydrolase	-

Sequence

Protein

• Length: 748 a.a.
• Molecular weight: 83113.90 Da
• Isoelectric Point: 4.8126

>NTDB_id=697963 M5C73_RS02660 WP_098383584.1 520096..522342(+) (clpC) [Lactococcus lactis strain WiKim0124]
MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALHGQDFNGAAST
QTPPTQTGGRGPRGPQNPRAKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTA
VVEGLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMD
AGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAH
LSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAETKKNEATQAEDFEKAAHFRDQITKLRELQNHEVS
DDEIPVITEKDIEQIVEQKTHIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKIAKAIRRSRVGLGKPNRPIGSFLFV
GPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHP
DVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKVEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEF
SALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRTIQENIEDSIADFYIEHPEYKELV
ADLIDDKIVISNQAQEAAETTDEKVPAE

Nucleotide

• Length: 2247 bp

>NTDB_id=697963 M5C73_RS02660 WP_098383584.1 520096..522342(+) (clpC) [Lactococcus lactis strain WiKim0124]
ATGCTTTGTCAAAATTGTAATATTAATGAAGCGACGATTCACCTTTACACAAGTGTAAATGGTCAGAAAAAACAAATTGA
TTTGTGCCAAAACTGTTATCAAATTATGAAATCTGGCGGTCAAGAAGCTTTATTTGGCGCAGGAAATGCCTCAAATGGAA
ATTCTGATGAACCATTTAATCCATTTAATGATATCTTTAGTGCTTTGCACGGTCAAGATTTTAATGGAGCAGCAAGCACT
CAAACTCCACCAACACAAACAGGTGGACGTGGTCCGCGCGGTCCACAAAATCCTCGGGCAAAACAACCTAAAGGAATGTT
AGAAGAATTTGGAATTAACATCACAGAGTCAGCTCGTCGTGGCGAAATTGACCCAGTGATTGGGCGTGATGAAGAAATTA
AACGTGTCATTGAGATTTTAAATCGTAGGACTAAGAATAATCCTGTATTAATTGGTGAACCTGGTGTTGGTAAAACAGCA
GTTGTTGAAGGTTTAGCGCAAAAAATTGTGGACGGAGATGTGCCGCAAAAACTACAAAATAAAGAAGTGATTCGTCTTGA
TGTTGTTTCTCTTGTTCAAGGAACAGGAATTCGTGGACAATTTGAAGAACGGATGCAAAAATTAATGGATGAAATCAGAA
AACGTAATGATGTGATTATGTTTATTGATGAAATTCATGAAATTGTTGGTGCTGGTTCTGCCGGTGATGGCAATATGGAT
GCAGGAAATATCCTAAAACCTGCGCTCGCGCGTGGTGAGCTTCAATTGGTCGGAGCAACAACGCTCAATGAATATCGCAT
CATTGAAAAAGATGCTGCGCTTGAACGCCGGATGCAACCAGTTAAAGTCGATGAACCATCAGTTGATGAAACAATTACTA
TTTTGCGAGGTATTCAAGCACGTTATGAAGATTATCATCACGTGAAATACACTGATGAGGCTATTGAAGCAGCCGCTCAT
TTGTCAAATCGTTACATTCAAGACCGTTTCTTACCAGATAAAGCCATTGACCTTTTGGATGAGTCTGGTTCTAAGAAAAA
TCTAACCTTGAAATTTGTTGATCCTGAAGATATTAATCGTCGGATTGCGGATGCAGAAACGAAGAAAAATGAAGCAACAC
AGGCTGAAGATTTTGAAAAAGCCGCTCATTTCCGTGACCAAATCACTAAACTTCGTGAATTACAAAATCATGAAGTTTCA
GATGATGAAATTCCTGTCATCACTGAAAAAGATATTGAACAAATTGTTGAGCAAAAAACACATATTCCAGTTGGTGATTT
GAAAGAAAAAGAACAAACCCAATTGATTAATTTGGCTGATGATTTGAAAGCACATGTGATTGGTCAGGATGAAGCAGTGG
ATAAGATTGCTAAAGCTATCCGTCGTTCTCGTGTGGGACTTGGTAAACCTAATCGTCCAATTGGTTCTTTCCTTTTCGTT
GGTCCAACAGGTGTTGGTAAAACAGAACTTGCTAAACAATTGGCTAAAGAATTATTTGGCTCAAGCGAAAGTATGATTCG
TTTTGACATGTCGGAATACATGGAAAAACATTCGGTGGCCAAATTAATTGGAGCCCCTCCAGGATATGTGGGTTATGAAG
AAGCTGGTCAATTGACTGAACGTGTTCGTCGTAATCCCTACAGTTTGATTTTATTAGATGAAATCGAAAAAGCACATCCA
GATGTGATGCACATGTTCTTGCAAATTCTTGAAGATGGACGTCTGACAGACGCACAAGGACGGACAGTATCCTTTAAAGA
TAGTTTGATTATTATGACTTCTAATGCCGGAACTGGTAAAGTTGAAGCCTCTGTCGGATTTGGTGCTGCTCGTGAGGGAC
GAACTAAATCAGTGCTTGGTCAGCTTGGCGATTTCTTTAGCCCTGAATTCATGAACCGTTTTGACGGAATAATTGAATTC
TCTGCTTTGAGCAAAGAAAATCTCCTTAAAATTGTTGATTTGATGCTTGATGAAGTCAACGAACAAATTGGACGTAATGA
TATTCATCTTAGTGTCACTCAAGCAGCAAAAGAAAAATTAGTTGATCTAGGTTACAATCCAGCAATGGGTGCAAGACCAC
TTCGTAGAACAATTCAAGAAAATATCGAAGATTCAATTGCTGACTTCTATATTGAACACCCTGAATACAAAGAATTGGTT
GCTGATTTGATTGATGATAAAATTGTTATCTCTAATCAAGCTCAAGAAGCAGCAGAAACGACTGATGAAAAAGTTCCTGC
TGAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (287-386)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (643-713)

• AAA domain (Cdc48 subfamily) (AAA_2) (472-635)

• ATPase family associated with various cellular activities (AAA) (AAA) (149-268)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	97.727	100	0.977
clpE	Streptococcus mutans UA159	76.026	100	0.767
clpE	Streptococcus pneumoniae Rx1	73.781	100	0.749
clpE	Streptococcus pneumoniae D39	73.781	100	0.749
clpE	Streptococcus pneumoniae R6	73.781	100	0.749
clpE	Streptococcus pneumoniae TIGR4	73.781	100	0.749
clpC	Bacillus subtilis subsp. subtilis str. 168	51.672	87.968	0.455
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.635	81.952	0.39
clpC	Streptococcus pneumoniae Rx1	46.635	83.422	0.389
clpC	Streptococcus pneumoniae D39	46.635	83.422	0.389
clpC	Streptococcus pneumoniae TIGR4	46.635	83.422	0.389
clpC	Streptococcus thermophilus LMD-9	46.104	82.353	0.38
clpC	Streptococcus thermophilus LMG 18311	45.942	82.353	0.378
clpC	Streptococcus mutans UA159	45.631	82.62	0.377