Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   DOM81_RS05675 Genome accession   NZ_AP018447
Coordinates   1125426..1127267 (+) Length   613 a.a.
NCBI ID   WP_172580137.1    Uniprot ID   -
Organism   Helicobacter cinaedi strain P06D0798     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1120426..1132267
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DOM81_RS05645 mog 1120842..1121372 (+) 531 WP_109204990.1 molybdopterin adenylyltransferase -
  DOM81_RS05650 moaC 1121394..1121870 (+) 477 WP_109204989.1 cyclic pyranopterin monophosphate synthase MoaC -
  DOM81_RS05655 rmuC 1121880..1123223 (+) 1344 WP_110581619.1 DNA recombination protein RmuC -
  DOM81_RS05660 nadB 1123238..1124683 (-) 1446 WP_110581618.1 L-aspartate oxidase -
  DOM81_RS05665 - 1124684..1124932 (-) 249 WP_002956815.1 hypothetical protein -
  DOM81_RS05670 - 1124924..1125382 (+) 459 WP_231900552.1 hypothetical protein -
  DOM81_RS05675 uvrC 1125426..1127267 (+) 1842 WP_172580137.1 excinuclease ABC subunit UvrC Machinery gene
  DOM81_RS05680 - 1127264..1128745 (+) 1482 WP_014666647.1 hypothetical protein -
  DOM81_RS05685 - 1128755..1130257 (+) 1503 WP_002956819.1 sensor histidine kinase -
  DOM81_RS05690 - 1130260..1130949 (+) 690 WP_002956820.1 response regulator -

Sequence

Protein


Download         Length: 613 a.a.        Molecular weight: 70730.31 Da        Isoelectric Point: 9.7723

>NTDB_id=69702 DOM81_RS05675 WP_172580137.1 1125426..1127267(+) (uvrC) [Helicobacter cinaedi strain P06D0798]
MYSLLFTLQNLPTQPGIYQYFDKDDNLLYVGKAKNLKNRIKSYFSIHNDIITPKANLSQRIALMVSQVAKIHTLLTQSQE
DALILENSLIKSLKPKYNILLRDDKTYPYIYIDTSATFPRFEITRKVLQSKHIEYFGPFVSGARELLDSLYDALPLVQKK
SCLKGKKACIFHQIHKCPAPCENKISQSQYAEYITQAKAFIDDRKGLIEILESKMQILSHNLQFEEAAKIRDRIQKLKTL
KTQSIIDIMSGDYDIFLLDSAGQNHILMMLFIRNGRIVSSDFSFIHQEIHSQNLAQLYTQALLNHYKTPLPLPPKEILIP
HFDFQDKDEKDDLQKILQAQTQSHLKITQPQKGTKYNLLQLAKKNAQEILTLHTKEQKNAQNENTTLYALKDLCNLSQVP
YRIEIFDTSHHSGSHNVGGMVVYENGEFIRSAYRRFELHSSDEYSQMSEMLTRRAKKFESNPPPDLWLLDGGKAQINLAL
DILKSVGANVDIIAIAKMKYNAKAYRAKGNALDILRTQNAEFKLSTNDKRLQFCQKLRDEVHRYAITYHRNKKQKDIHKI
QIQKGSDMDSSYSKAQIKRLLDYFGSFHAIQNAPKEQIENALSRSFKSNKDSK

Nucleotide


Download         Length: 1842 bp        

>NTDB_id=69702 DOM81_RS05675 WP_172580137.1 1125426..1127267(+) (uvrC) [Helicobacter cinaedi strain P06D0798]
ATATATAGTCTGCTTTTTACCCTGCAAAATCTCCCTACACAGCCCGGAATCTACCAATATTTTGATAAAGATGATAACTT
GCTCTATGTCGGCAAGGCTAAAAATCTAAAAAATCGCATAAAAAGCTATTTTTCTATCCATAATGACATCATCACGCCAA
AGGCTAACCTTAGCCAAAGAATAGCCCTTATGGTATCCCAAGTGGCTAAGATTCACACTTTACTTACACAAAGCCAAGAA
GATGCCCTTATCCTTGAAAACTCCCTTATCAAAAGCCTAAAGCCAAAGTATAATATTCTTTTGCGTGATGATAAAACTTA
TCCTTATATTTATATTGATACTTCTGCTACTTTTCCACGATTTGAAATCACTCGCAAGGTGCTACAAAGTAAGCATATTG
AGTATTTTGGTCCTTTTGTGAGTGGAGCTAGAGAGCTGCTTGATAGTCTCTATGATGCCCTGCCCCTTGTGCAGAAAAAA
TCCTGCCTTAAAGGCAAAAAGGCGTGTATATTTCATCAGATTCATAAATGCCCTGCCCCTTGTGAAAATAAAATCTCTCA
AAGTCAATATGCAGAGTATATTACACAAGCAAAGGCGTTTATAGATGATAGAAAAGGACTTATAGAGATTTTAGAATCTA
AAATGCAGATACTCTCACACAATCTACAATTTGAAGAGGCAGCAAAGATACGAGATAGAATCCAAAAGCTAAAAACACTA
AAAACCCAATCTATTATTGATATTATGAGCGGAGATTATGATATTTTCCTGCTTGATTCAGCAGGGCAAAATCATATCCT
TATGATGCTTTTTATCCGCAATGGACGCATTGTCTCAAGTGATTTTTCATTTATCCACCAAGAGATTCACAGCCAAAACC
TAGCCCAACTCTACACCCAAGCCTTACTTAATCACTATAAAACCCCTCTTCCCTTGCCACCAAAGGAGATTCTTATCCCG
CATTTTGACTTCCAAGACAAAGATGAAAAAGATGATTTACAAAAGATTTTGCAAGCCCAAACACAAAGTCATCTCAAAAT
CACCCAACCACAAAAAGGCACAAAATATAACCTTTTGCAACTTGCTAAAAAGAACGCCCAAGAAATCCTAACTTTGCATA
CCAAAGAGCAAAAGAACGCCCAAAATGAAAACACCACTTTATACGCTCTAAAAGATTTATGCAATCTCTCTCAAGTGCCT
TATAGGATAGAGATCTTTGACACCTCTCATCATAGCGGAAGCCACAATGTAGGCGGAATGGTAGTGTATGAAAATGGCGA
GTTTATCCGCAGTGCTTACAGACGCTTTGAGCTTCATAGCAGTGATGAATACTCTCAAATGAGTGAAATGCTAACACGCA
GGGCAAAAAAATTTGAATCCAATCCGCCACCAGATTTATGGCTACTTGATGGGGGCAAGGCTCAAATCAACCTAGCACTT
GACATTCTAAAAAGTGTGGGGGCAAATGTAGATATTATCGCCATTGCCAAAATGAAATATAATGCCAAAGCCTATCGCGC
TAAAGGCAATGCCCTTGATATTTTACGCACACAAAATGCGGAGTTTAAACTTAGCACAAACGATAAAAGACTACAATTCT
GCCAAAAGCTCCGCGATGAAGTGCATAGATATGCTATCACTTATCATCGCAACAAAAAGCAAAAAGACATACACAAGATT
CAGATTCAAAAAGGAAGTGATATGGATAGCTCTTATAGCAAGGCTCAAATTAAACGACTTTTAGATTATTTTGGCTCATT
CCACGCCATTCAAAACGCTCCAAAAGAGCAGATAGAAAATGCTCTTTCACGCTCTTTTAAAAGTAATAAAGATTCAAAAT
GA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(207-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(392-546)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

51.078

98.369

0.502

Multiple sequence alignment