Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   DOM78_RS04415 Genome accession   NZ_AP018446
Coordinates   857781..859679 (-) Length   632 a.a.
NCBI ID   WP_110505469.1    Uniprot ID   -
Organism   Helicobacter cinaedi strain P03D0629     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 852781..864679
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DOM78_RS04400 - 854099..854788 (-) 690 WP_002956820.1 response regulator -
  DOM78_RS04405 - 854791..856293 (-) 1503 WP_002956819.1 sensor histidine kinase -
  DOM78_RS04410 - 856303..857784 (-) 1482 WP_014666647.1 hypothetical protein -
  DOM78_RS04415 uvrC 857781..859679 (-) 1899 WP_110505469.1 excinuclease ABC subunit UvrC Machinery gene
  DOM78_RS04420 - 859666..860124 (-) 459 WP_231900552.1 hypothetical protein -
  DOM78_RS04425 - 860116..860364 (+) 249 WP_002956815.1 hypothetical protein -
  DOM78_RS04430 nadB 860365..861810 (+) 1446 WP_104716683.1 L-aspartate oxidase -
  DOM78_RS04435 rmuC 861825..863168 (-) 1344 WP_110505468.1 DNA recombination protein RmuC -
  DOM78_RS04440 moaC 863178..863654 (-) 477 WP_014666652.1 cyclic pyranopterin monophosphate synthase MoaC -
  DOM78_RS04445 mog 863676..864206 (-) 531 WP_014666653.1 molybdopterin adenylyltransferase -

Sequence

Protein


Download         Length: 632 a.a.        Molecular weight: 72929.91 Da        Isoelectric Point: 9.8989

>NTDB_id=69694 DOM78_RS04415 WP_110505469.1 857781..859679(-) (uvrC) [Helicobacter cinaedi strain P03D0629]
MPKHKNIQAQNIHKISKTSIYSLLFTLQNLPTQPGIYQYFDKDDNLLYVGKAKNLKNRIKSYFSIHNDIITPKANLSQRI
ALMVSQVAKIHTLLTQSQEDALILENSLIKSLKPKYNILLRDDKTYPYIYIDTSATFPRFEITRKVLQSKHIEYFGPFVS
GARELLDSLYDALPLVQKKSCLKGKKACIFHQIHKCPAPCENKISQSQYAEYITQAKAFIDDRKGLIEILESKMQILSHN
LQFEEAAKIRDRIQKLKTLKTQSIIDIMSGDYDIFLLDSAGQNHILMMLFIRNGRIVSSDFSFIHQEIHSQNLAQLYTQA
LLNHYKTPLPLPPKEILIPHFDFQDKDEKDDLQKILQAQTQSHLKITQPQKGTKYNLLQLAKKNAQEILTLHTKEQKNAQ
NENTTLYALKDLCNLSQMPYRIEIFDTSHHSGSHNVGGMVVYENGEFIRSAYRRFELHSSDEYSQMSEMLTRRAKKFESN
PPPDLWLLDGGKAQINLALDILKSVGANVDIIAIAKMKYNAKAYRAKGNALDILRTQNAEFKLSTNDKRLQFCQKLRDEV
HRYAITYHRNKKQKDIHKIQIQKGSDMDSSYSKAQIKRLLDYFGSFHAIQNAPKEQIENALSRSFKSNKDSK

Nucleotide


Download         Length: 1899 bp        

>NTDB_id=69694 DOM78_RS04415 WP_110505469.1 857781..859679(-) (uvrC) [Helicobacter cinaedi strain P03D0629]
ATGCCCAAGCATAAAAACATTCAGGCACAAAACATTCACAAAATATCCAAAACATCAATATATAGTCTGCTTTTTACCCT
GCAAAATCTCCCTACACAGCCCGGAATCTACCAATATTTTGATAAAGATGATAACTTGCTCTATGTCGGCAAGGCTAAAA
ATCTAAAAAATCGCATAAAAAGCTATTTTTCTATCCATAATGACATCATCACGCCAAAGGCTAACCTTAGCCAAAGAATA
GCCCTTATGGTATCCCAAGTGGCTAAGATTCACACTTTACTTACACAAAGCCAAGAAGATGCCCTTATCCTTGAAAACTC
CCTTATCAAAAGCCTAAAGCCAAAGTATAATATTCTTTTGCGTGATGATAAAACTTATCCTTATATTTATATTGATACTT
CTGCTACTTTTCCACGATTTGAAATCACTCGCAAGGTGCTACAAAGTAAGCATATTGAGTATTTTGGTCCTTTTGTGAGT
GGAGCTAGAGAGCTGCTTGATAGTCTCTATGATGCCCTGCCCCTTGTGCAGAAAAAATCCTGCCTTAAAGGCAAAAAGGC
GTGTATATTTCATCAGATTCATAAATGCCCTGCCCCTTGTGAAAATAAAATCTCTCAAAGTCAATATGCAGAGTATATTA
CACAAGCAAAGGCGTTTATAGATGATAGAAAAGGACTTATAGAGATTTTAGAATCTAAAATGCAGATACTCTCACACAAT
CTACAATTTGAAGAGGCAGCAAAGATACGAGATAGAATCCAAAAGCTAAAAACACTAAAAACCCAATCTATTATTGATAT
TATGAGCGGAGATTATGATATTTTCCTGCTTGATTCAGCAGGGCAAAATCATATCCTTATGATGCTTTTTATCCGCAATG
GACGCATTGTCTCAAGTGATTTTTCATTTATCCACCAAGAGATTCACAGCCAAAACCTAGCCCAACTCTACACCCAAGCC
TTACTTAATCACTATAAAACCCCTCTTCCCTTGCCACCAAAGGAGATTCTTATCCCGCATTTTGACTTCCAAGACAAAGA
TGAAAAAGATGATTTACAAAAGATTTTGCAAGCCCAAACACAAAGTCATCTCAAAATCACCCAACCACAAAAAGGCACAA
AATATAACCTTTTGCAACTTGCTAAAAAGAACGCCCAAGAAATCCTAACTTTGCATACCAAAGAGCAAAAGAACGCCCAA
AATGAAAACACCACTTTATACGCTCTAAAAGATTTATGCAATCTCTCTCAAATGCCTTATAGGATAGAGATCTTTGACAC
CTCTCATCATAGCGGAAGCCACAATGTAGGCGGAATGGTAGTGTATGAAAATGGCGAGTTTATCCGCAGTGCTTACAGAC
GCTTTGAGCTTCATAGCAGTGATGAATACTCTCAAATGAGTGAAATGCTAACACGCAGGGCAAAAAAATTTGAATCCAAT
CCGCCACCAGATTTATGGCTACTTGATGGGGGCAAGGCTCAAATCAACCTAGCACTTGACATTCTAAAAAGTGTGGGGGC
AAATGTAGATATTATCGCCATTGCCAAAATGAAATATAATGCCAAAGCCTATCGCGCTAAAGGCAATGCCCTTGATATTT
TACGCACACAAAATGCGGAGTTTAAACTTAGCACAAACGATAAAAGACTACAATTCTGCCAAAAGCTCCGCGATGAAGTG
CATAGATATGCTATCACTTATCATCGCAACAAAAAGCAAAAAGACATACACAAGATTCAGATTCAAAAAGGAAGTGATAT
GGATAGCTCTTATAGCAAGGCTCAAATTAAACGACTTTTAGATTATTTTGGCTCATTCCACGCCATTCAAAACGCTCCAA
AAGAGCAGATAGAAAATGCTCTTTCACGCTCTTTTAAAAGTAATAAAGATTCAAAATGA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(34-117)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(411-565)

UvrB/uvrC motif (UVR)

(226-258)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

51.333

94.937

0.487

Multiple sequence alignment