Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BVS141_RS05970 Genome accession   NZ_AP018402
Coordinates   1151651..1152307 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain S141     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1146651..1157307
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BVS141_RS05945 (BVS141_11820) oppF 1147181..1148098 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  BVS141_RS05950 (BVS141_11830) - 1148205..1149392 (+) 1188 WP_079891086.1 putative glycoside hydrolase -
  BVS141_RS05955 (BVS141_11840) - 1149510..1150088 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  BVS141_RS05960 (BVS141_11850) spx 1150267..1150662 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  BVS141_RS05965 (BVS141_11860) - 1150719..1151375 (-) 657 WP_060562158.1 TerC family protein -
  BVS141_RS20010 - 1151558..1151668 (+) 111 Protein_1100 adaptor protein MecA -
  BVS141_RS05970 (BVS141_11870) mecA 1151651..1152307 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  BVS141_RS05975 (BVS141_11880) - 1152458..1153618 (+) 1161 WP_060562159.1 competence protein CoiA family protein -
  BVS141_RS05980 (BVS141_11890) pepF 1153846..1155675 (+) 1830 WP_101536289.1 oligoendopeptidase F Regulator
  BVS141_RS19890 (BVS141_11900) - 1155713..1155880 (-) 168 WP_003155026.1 hypothetical protein -
  BVS141_RS05985 (BVS141_11910) spxH 1156166..1157068 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=69497 BVS141_RS05970 WP_003155032.1 1151651..1152307(+) (mecA) [Bacillus velezensis strain S141]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=69497 BVS141_RS05970 WP_003155032.1 1151651..1152307(+) (mecA) [Bacillus velezensis strain S141]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment