Detailed information NTG0693343

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NAA64_RS04825
• Genome accession: NZ_CP097887
• Coordinates: 1013175..1014218 (+)
• Length: 347 a.a.
• NCBI ID: WP_002509180.1
• Uniprot ID: A0A7V7SQH4
• Organism: Staphylococcus arlettae strain SA283
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1008175..1019218

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NAA64_RS04800 (NAA64_04800)	-	1008855..1009580 (+)	726	WP_021459029.1	type 1 glutamine amidotransferase	-
NAA64_RS04805 (NAA64_04805)	-	1010067..1011053 (-)	987	WP_103388397.1	FUSC family protein	-
NAA64_RS04810 (NAA64_04810)	map	1011219..1011971 (+)	753	WP_021459027.1	type I methionyl aminopeptidase	-
NAA64_RS04815 (NAA64_04815)	-	1012074..1012460 (+)	387	WP_002509178.1	hypothetical protein	-
NAA64_RS04820 (NAA64_04820)	liaF	1012477..1013178 (+)	702	WP_002509179.1	cell wall-active antibiotics response protein LiaF	-
NAA64_RS04825 (NAA64_04825)	vraS	1013175..1014218 (+)	1044	WP_002509180.1	sensor histidine kinase	Regulator
NAA64_RS04830 (NAA64_04830)	vraR	1014208..1014837 (+)	630	WP_002509181.1	response regulator transcription factor	Regulator
NAA64_RS04835 (NAA64_04835)	-	1014900..1015979 (-)	1080	WP_103388398.1	YihY/virulence factor BrkB family protein	-
NAA64_RS04840 (NAA64_04840)	-	1016259..1016543 (-)	285	WP_002509183.1	hypothetical protein	-
NAA64_RS04845 (NAA64_04845)	-	1016550..1017014 (-)	465	WP_002509184.1	low molecular weight protein-tyrosine-phosphatase	-
NAA64_RS04850 (NAA64_04850)	-	1017150..1017353 (+)	204	WP_021459025.1	DUF1128 family protein	-
NAA64_RS04855 (NAA64_04855)	-	1017365..1018603 (+)	1239	WP_103388399.1	aminopeptidase	-
NAA64_RS04860 (NAA64_04860)	-	1018637..1019164 (+)	528	WP_103388400.1	acyl-CoA thioesterase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39859.16 Da
• Isoelectric Point: 5.2631

>NTDB_id=693343 NAA64_RS04825 WP_002509180.1 1013175..1014218(+) (vraS) [Staphylococcus arlettae strain SA283]
MNHYIRAIGSMLILVYSTLIAFFFIDKIFVNIMYFQGMFYTQIFGIPVFLFLNLLIILLCIIVGSVLAYKINQQNHWLQT
QIERSIEGETVGINDQDIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESQLTPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVIHDI
EDFTVPKGIEDHLFRITQEAISNTLRHSNGTKVTIELFNQEAYLLLRIQDNGIGFNVDDKAEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLDKEDIDAN

Nucleotide

• Length: 1044 bp

>NTDB_id=693343 NAA64_RS04825 WP_002509180.1 1013175..1014218(+) (vraS) [Staphylococcus arlettae strain SA283]
ATGAATCACTACATTAGAGCAATAGGCTCTATGCTAATATTAGTATATAGTACATTAATTGCTTTTTTCTTTATAGATAA
AATATTTGTAAATATTATGTATTTTCAAGGTATGTTTTATACCCAAATATTTGGTATTCCAGTATTTTTATTTTTAAATT
TGCTCATAATTTTATTATGTATCATTGTAGGATCGGTTTTAGCTTATAAAATAAACCAGCAAAACCATTGGCTACAAACA
CAAATTGAACGTTCAATTGAAGGAGAAACAGTAGGGATTAATGACCAAGATATAGAACTTTATAATGAAACTATAGAGCT
CTATCAAACGTTAGTTCCACTCAATCAAGAAGTACATAAACTGCGAATGAAGACCCAAAATTTAACAAATGAATCTTATA
ATTTAAACGATGTCAAAGTTAAAAAAATAATCGAAGATGAACGACAAAGATTGGCTAGGGAATTACATGATTCAGTGAGT
CAGCAACTTTTTGCAGCTAGCATGATGTTATCAGCTATCAAAGAATCTCAATTAACACCACCTTTAGATCAACAAATCCC
TACATTAGAAAAAATGGTACAAGATTCTCAACTAGAAATGAGAGCATTATTACTACATTTAAGACCAATTGGTTTAAAAG
ATAAGTCTCTCGGAGAAGGTATTAAAGATTTAGTTGTCGATTTACAGAAAAAAGTACCAATGAAGGTCATACATGACATT
GAAGATTTTACTGTACCTAAAGGTATTGAAGATCATTTGTTTCGTATTACGCAAGAAGCGATATCCAATACATTACGTCA
TTCCAACGGTACAAAAGTAACAATTGAATTATTTAATCAAGAAGCATATTTATTATTACGTATTCAAGATAACGGTATTG
GTTTTAACGTAGATGATAAAGCTGAACAAAGTTATGGATTGAAAAATATGCGGGAGCGTGCATTAGAAATAGGTGCCACA
TTCCATATTGTATCGCTGCCTGATTCAGGTACTAGAATAGAAGTGAAAGCACCATTAGATAAGGAGGATATAGATGCCAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A7V7SQH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.63	98.847	0.876