Detailed information NTG0692957

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: M9H69_RS09720
• Genome accession: NZ_CP097843
• Coordinates: 1935572..1938004 (-)
• Length: 810 a.a.
• NCBI ID: WP_250315509.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain HP01
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1930572..1943004

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M9H69_RS09695 (M9H69_09695)	-	1931035..1931721 (-)	687	WP_250315505.1	YoaK family protein	-
M9H69_RS09700 (M9H69_09700)	-	1931848..1932531 (-)	684	WP_096421485.1	hypothetical protein	-
M9H69_RS09705 (M9H69_09705)	-	1932805..1933578 (-)	774	WP_250315506.1	NUDIX hydrolase	-
M9H69_RS09710 (M9H69_09710)	pnuC	1933580..1934359 (-)	780	WP_250315507.1	nicotinamide riboside transporter PnuC	-
M9H69_RS09715 (M9H69_09715)	-	1934369..1935427 (-)	1059	WP_250315508.1	AAA family ATPase	-
M9H69_RS09720 (M9H69_09720)	clpC	1935572..1938004 (-)	2433	WP_250315509.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
M9H69_RS09725 (M9H69_09725)	-	1938006..1938464 (-)	459	WP_001211258.1	CtsR family transcriptional regulator	-
M9H69_RS09730 (M9H69_09730)	-	1938931..1939140 (+)	210	WP_001044018.1	CPCC family cysteine-rich protein	-
M9H69_RS09735 (M9H69_09735)	-	1939175..1939390 (+)	216	WP_250315510.1	hypothetical protein	-
M9H69_RS09740 (M9H69_09740)	-	1939659..1939961 (-)	303	WP_250315511.1	hypothetical protein	-
M9H69_RS09745 (M9H69_09745)	-	1940010..1940222 (-)	213	WP_250315512.1	hypothetical protein	-
M9H69_RS09750 (M9H69_09750)	-	1940327..1941055 (-)	729	WP_250315513.1	ABC transporter ATP-binding protein	-
M9H69_RS09755 (M9H69_09755)	-	1941055..1942062 (-)	1008	WP_250315514.1	ABC transporter substrate-binding protein	-
M9H69_RS09760 (M9H69_09760)	-	1942101..1942859 (-)	759	WP_250315515.1	ABC transporter permease	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 90365.33 Da
• Isoelectric Point: 6.3045

>NTDB_id=692957 M9H69_RS09720 WP_250315509.1 1935572..1938004(-) (clpC) [Streptococcus oralis strain HP01]
MNYSKALNECIESAYMIASHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETDYSQDETFTELPF
SHRLEVLFAEAEYVASVVHAKVLGTEHVLYAILHDGNALATRILERAGFSYEDQKDQVRIAALRRNLEERAGWTREDLKA
LRQRHRTVADKQNSMANMMGMPQNPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGNVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGKVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSLADSMTILQGLKATYEKHHRVKITDEAVET
AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVRMAESDLSPADKALMDGKWKQAGQLIAKEQELPVYKDLVTESDI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGVTALRDDKTVGFGAKDIRFDQENMEKRIFEELKKAYRPEFINRIDEKVVFHSLDS
EHMQEIVKIMVKPLIASLAEKGIDLKLQASALKLLASHGYNPEMGARPLRRTLQTEVEDKLAELLLKGELVAGKSLKIGV
KAGQLKFDIA

Nucleotide

• Length: 2433 bp

>NTDB_id=692957 M9H69_RS09720 WP_250315509.1 1935572..1938004(-) (clpC) [Streptococcus oralis strain HP01]
ATGAACTATTCAAAAGCATTGAATGAATGTATCGAAAGTGCCTACATGATTGCCAGCCATTTTGGAGCTCGATATCTAGA
GTCTTGGCATTTATTGATTGCCATGTCCAATCACAGTTATAGTGTGGCAGGTGCCACTCTAAATGATTATCCTTATGAAA
TGGACCGTTTAGAAGAGGTTGCGTTGGAACTGACTGAAACGGACTATAGCCAAGACGAAACCTTTACGGAATTGCCTTTT
TCCCATCGTTTGGAGGTTCTCTTTGCAGAAGCAGAGTATGTGGCCTCAGTGGTCCATGCAAAGGTGCTAGGGACAGAGCA
TGTCCTCTATGCGATTTTGCATGATGGCAATGCTTTGGCAACTCGCATCTTGGAGAGAGCAGGCTTTTCTTATGAAGACC
AGAAAGATCAGGTCAGAATTGCTGCCCTTCGTCGCAACTTAGAGGAACGTGCAGGTTGGACAAGAGAAGACCTTAAGGCT
TTGCGTCAGCGCCACCGTACCGTGGCAGATAAGCAAAATTCTATGGCCAATATGATGGGCATGCCTCAGAATCCAAGTGG
CGGTCTAGAGGACTACACGCATGACCTGACGGAGCAAGCGCGCTCTGGCAAGTTAGAGCCAGTTATCGGTCGGGACAAGG
AAATCTCACGTATGATTCAAATCTTGAGCCGGAAGACCAAGAACAATCCTGTCTTGGTTGGAGATGCTGGTGTCGGGAAA
ACAGCTCTGGCACTTGGACTTGCCCAGCGTATTGCTAGCGGGAATGTACCAGCTGAAATGGCCAAGATGCGCGTGTTAGA
GCTTGATTTGATGAATGTTGTTGCGGGGACACGTTTCCGTGGAGATTTTGAAGAGCGTATGAACAATATCATCAAGGATA
TCGAGGAAGATGGCAAAGTGATCCTCTTTATCGATGAACTCCACACCATCATGGGTTCTGGTAGCGGTATTGATTCGACT
CTGGATGCGGCCAATATCTTGAAGCCAGCCTTGGCACGTGGAACTTTGAGAACGGTTGGTGCAACCACTCAGGAAGAATA
CCAAAAACACATCGAAAAAGATGCAGCCCTTTCTCGTCGTTTTGCTAAAGTGACTATTGAAGAGCCAAGTTTAGCTGACA
GCATGACCATTTTGCAAGGTTTGAAGGCTACCTATGAGAAACACCACCGTGTGAAAATCACAGATGAAGCTGTCGAAACA
GCCGTTAAGATGGCGCATCGTTACTTGACTAGTCGTCACTTGCCAGACTCTGCTATCGACCTCTTGGATGAGGCGGCAGC
AACAGTGCAAAATAAATCCAAGCATGTGAGAATGGCCGAATCCGACTTGAGTCCAGCTGACAAGGCCTTGATGGATGGCA
AGTGGAAACAAGCAGGTCAGTTAATCGCAAAAGAACAAGAATTGCCTGTCTATAAAGACTTGGTAACAGAGTCTGATATT
TTGACCACCTTGAGTCGTTTGTCAGGTATCCCAGTCCAAAAACTAACGCAAACAGATGCTAAGAAATACCTGAACTTGGA
AGCTGAACTACACAAACGTGTTATCGGCCAAGATCAAGCTGTTTCAAGTATTAGTCGTGCCATTCGTCGCAACCAGTCAG
GTATTCGCAGTCACAAGCGTCCGATTGGTTCCTTTATGTTTTTAGGACCGACGGGTGTCGGGAAGACCGAATTGGCTAAG
GCTTTGGCAGAAGTCCTCTTTGATGACGAATCAGCCCTTATCCGCTTTGATATGAGTGAGTATATGGAGAAATTTGCGGC
TAGCCGTCTCAACGGAGCTCCTCCGGGTTATGTAGGCTACGAAGAAGGTGGGGAGTTGACCGAGAAGGTTCGCAATAAAC
CTTACTCAGTGCTTCTCTTTGACGAGGTTGAAAAAGCCCACCCAGATATCTTTAATGTCCTCTTGCAAGTCTTGGACGAT
GGAGTTCTAACAGACAGCAAGGGTCGCAAGGTTGATTTTTCAAATACCATCATTATCATGACTTCAAACCTTGGTGTGAC
AGCCCTTCGTGATGACAAGACTGTCGGTTTTGGGGCCAAGGACATTCGTTTTGACCAGGAAAATATGGAAAAACGAATCT
TCGAAGAGTTGAAAAAAGCTTATCGACCTGAGTTTATCAACCGTATTGATGAAAAGGTGGTCTTCCACAGCTTGGATAGC
GAACACATGCAGGAAATTGTCAAGATCATGGTTAAACCATTGATTGCTAGCCTAGCAGAGAAAGGCATCGACTTGAAACT
ACAAGCTTCGGCACTGAAGTTACTAGCTAGTCACGGTTACAATCCAGAAATGGGAGCTCGTCCACTTCGTAGAACACTGC
AAACAGAGGTGGAAGACAAGTTGGCAGAACTCCTCCTCAAGGGAGAGTTGGTAGCAGGCAAGTCCCTCAAAATCGGCGTC
AAAGCTGGTCAATTAAAATTTGATATTGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (540-711)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (718-797)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (103-133)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-49)

• AAA lid domain (AAA_lid_9) (371-439)

• ATPase family associated with various cellular activities (AAA) (AAA) (231-362)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	95.926	100	0.959
clpC	Streptococcus pneumoniae D39	95.926	100	0.959
clpC	Streptococcus pneumoniae TIGR4	95.802	100	0.958
clpC	Streptococcus mutans UA159	67.405	100	0.677
clpC	Streptococcus thermophilus LMD-9	66.463	100	0.67
clpC	Streptococcus thermophilus LMG 18311	66.585	100	0.669
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.516	100	0.505
clpC	Bacillus subtilis subsp. subtilis str. 168	45.074	100	0.452
clpE	Streptococcus mutans UA159	48.631	76.667	0.373
clpC	Lactococcus lactis subsp. cremoris KW2	46.508	77.778	0.362