Detailed information
Bioinformatically predicted
Overview
| Name | recD | Type | Machinery gene |
| Locus tag | EP178_RS04470 | Genome accession | NZ_AP018377 |
| Coordinates | 766131..767876 (+) | Length | 581 a.a. |
| NCBI ID | WP_003688652.1 | Uniprot ID | A0AA44U7G6 |
| Organism | Neisseria gonorrhoeae strain FC428 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 730958..806005 | 766131..767876 | within | 0 |
| IS/Tn | 768563..769564 | 766131..767876 | flank | 687 |
Gene organization within MGE regions
Location: 730958..806005
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EP178_RS04250 (NgFC428_00743) | - | 730958..732028 (-) | 1071 | WP_010360162.1 | tyrosine-type recombinase/integrase | - |
| EP178_RS04255 (NgFC428_00744) | - | 732237..733016 (-) | 780 | WP_003688701.1 | ferredoxin--NADP reductase | - |
| EP178_RS04270 | - | 733608..733817 (-) | 210 | WP_003688699.1 | hypothetical protein | - |
| EP178_RS04275 (NgFC428_00746) | dinB | 733916..734974 (+) | 1059 | WP_003695315.1 | DNA polymerase IV | - |
| EP178_RS04280 (NgFC428_00747) | rep | 735044..737059 (-) | 2016 | WP_012503651.1 | DNA helicase Rep | - |
| EP178_RS04285 (NgFC428_00748) | aroD | 737079..737843 (-) | 765 | WP_003688696.1 | type I 3-dehydroquinate dehydratase | - |
| EP178_RS04290 (NgFC428_00749) | recA | 738043..739089 (+) | 1047 | WP_003688695.1 | recombinase RecA | Machinery gene |
| EP178_RS04305 (NgFC428_00750) | - | 739742..740077 (-) | 336 | WP_003688693.1 | YbaB/EbfC family nucleoid-associated protein | - |
| EP178_RS04310 (NgFC428_00751) | dnaX | 740158..742281 (-) | 2124 | WP_003695312.1 | DNA polymerase III subunit gamma/tau | - |
| EP178_RS04315 (NgFC428_00752) | mutL | 742376..744340 (-) | 1965 | WP_047926984.1 | DNA mismatch repair endonuclease MutL | - |
| EP178_RS04320 (NgFC428_00753) | - | 744484..744669 (+) | 186 | WP_003688687.1 | DUF3460 family protein | - |
| EP178_RS04325 (NgFC428_00754) | - | 744680..745348 (+) | 669 | WP_003688686.1 | class I SAM-dependent methyltransferase | - |
| EP178_RS04330 (NgFC428_00755) | - | 745348..746061 (+) | 714 | WP_003697104.1 | tetratricopeptide repeat protein | - |
| EP178_RS04335 (NgFC428_00756) | purE | 746109..746594 (+) | 486 | WP_003688684.1 | 5-(carboxyamino)imidazole ribonucleotide mutase | - |
| EP178_RS04345 (NgFC428_00757) | - | 746806..747613 (-) | 808 | Protein_752 | transposase | - |
| EP178_RS04355 | - | 747987..748352 (+) | 366 | Protein_753 | transposase | - |
| EP178_RS04360 (NgFC428_00759) | - | 748359..749384 (+) | 1026 | Protein_754 | autotransporter outer membrane beta-barrel domain-containing protein | - |
| EP178_RS04365 (NgFC428_00760) | - | 749579..750235 (-) | 657 | WP_003688682.1 | response regulator | - |
| EP178_RS04370 (NgFC428_00761) | - | 750232..752001 (-) | 1770 | WP_003688681.1 | histidine kinase | - |
| EP178_RS04375 (NgFC428_00762) | - | 752208..752822 (+) | 615 | WP_047917856.1 | molybdenum cofactor guanylyltransferase | - |
| EP178_RS04380 (NgFC428_00763) | - | 752985..753602 (+) | 618 | WP_010358100.1 | riboflavin synthase | - |
| EP178_RS04385 | - | 753610..754474 (+) | 865 | Protein_759 | ATP-binding protein | - |
| EP178_RS04390 (NgFC428_00766) | - | 754487..754921 (-) | 435 | WP_003688677.1 | Spy/CpxP family protein refolding chaperone | - |
| EP178_RS04395 (NgFC428_00767) | rpe | 755067..755750 (+) | 684 | WP_003688675.1 | ribulose-phosphate 3-epimerase | - |
| EP178_RS04405 (NgFC428_00768) | ruvB | 755995..757026 (-) | 1032 | WP_003688673.1 | Holliday junction branch migration DNA helicase RuvB | - |
| EP178_RS04410 (NgFC428_00769) | - | 757108..757416 (-) | 309 | WP_003688671.1 | hypothetical protein | - |
| EP178_RS04420 (NgFC428_00770) | - | 757835..759067 (-) | 1233 | WP_003702731.1 | multifunctional CCA addition/repair protein | - |
| EP178_RS04425 (NgFC428_00771) | - | 759146..760774 (-) | 1629 | WP_010951119.1 | ABC-F family ATPase | - |
| EP178_RS04430 (NgFC428_00772) | - | 760924..761298 (+) | 375 | WP_003688664.1 | arsenate reductase | - |
| EP178_RS04435 (NgFC428_00773) | - | 761347..762885 (+) | 1539 | WP_003695299.1 | SurA N-terminal domain-containing protein | - |
| EP178_RS04440 (NgFC428_00774) | recR | 762952..763569 (+) | 618 | WP_003688660.1 | recombination mediator RecR | - |
| EP178_RS04445 (NgFC428_00775) | - | 763625..763903 (-) | 279 | WP_003688659.1 | hypothetical protein | - |
| EP178_RS04460 (NgFC428_00776) | - | 764129..765376 (+) | 1248 | WP_003691197.1 | lipoprotein-releasing ABC transporter permease subunit | - |
| EP178_RS04465 (NgFC428_00777) | lolD | 765369..766064 (+) | 696 | WP_003688655.1 | lipoprotein-releasing ABC transporter ATP-binding protein LolD | - |
| EP178_RS04470 (NgFC428_00778) | recD | 766131..767876 (+) | 1746 | WP_003688652.1 | exodeoxyribonuclease V subunit alpha | Machinery gene |
| EP178_RS04475 | - | 767948..768594 (-) | 647 | Protein_773 | methyltransferase | - |
| EP178_RS04480 (NgFC428_00780) | - | 768602..769564 (+) | 963 | WP_127466217.1 | IS110 family transposase | - |
| EP178_RS13575 | - | 769693..770152 (-) | 460 | Protein_775 | methyltransferase | - |
| EP178_RS04490 (NgFC428_00782) | lon | 770404..772866 (+) | 2463 | WP_003688644.1 | endopeptidase La | - |
| EP178_RS04495 (NgFC428_00783) | - | 773048..773317 (+) | 270 | WP_003688640.1 | HU family DNA-binding protein | - |
| EP178_RS04500 (NgFC428_00784) | - | 773493..773927 (-) | 435 | WP_003688638.1 | hypothetical protein | - |
| EP178_RS04505 (NgFC428_00785) | - | 773920..775227 (-) | 1308 | WP_103195193.1 | homoserine dehydrogenase | - |
| EP178_RS04510 (NgFC428_00786) | - | 775423..775794 (+) | 372 | WP_003688636.1 | Mth938-like domain-containing protein | - |
| EP178_RS04515 (NgFC428_00787) | - | 775871..777793 (+) | 1923 | WP_003691184.1 | ATP-binding cassette domain-containing protein | - |
| EP178_RS04520 | - | 777756..778175 (+) | 420 | WP_229692939.1 | DUF4124 domain-containing protein | - |
| EP178_RS04525 (NgFC428_00788) | - | 778266..778778 (+) | 513 | WP_003693093.1 | hypothetical protein | - |
| EP178_RS04530 (NgFC428_00789) | - | 779208..779903 (-) | 696 | WP_033910499.1 | DUF4400 domain-containing protein | - |
| EP178_RS04535 (NgFC428_00790) | traD | 779893..781935 (-) | 2043 | WP_012503640.1 | type IV conjugative transfer system coupling protein TraD | - |
| EP178_RS04540 (NgFC428_00791) | mobH | 781932..784484 (-) | 2553 | WP_012503639.1 | MobH family relaxase | - |
| EP178_RS04545 (NgFC428_00792) | - | 784481..784900 (-) | 420 | WP_003693104.1 | hypothetical protein | - |
| EP178_RS04550 (NgFC428_00793) | - | 785411..785872 (+) | 462 | WP_012503638.1 | lytic transglycosylase domain-containing protein | - |
| EP178_RS04555 (NgFC428_00794) | - | 785842..786363 (+) | 522 | WP_003695285.1 | OmpA family protein | - |
| EP178_RS04560 (NgFC428_00795) | traA | 786419..786715 (+) | 297 | WP_003697092.1 | TraA family conjugative transfer protein | - |
| EP178_RS04565 (NgFC428_00796) | traL | 786737..787018 (+) | 282 | WP_003693110.1 | type IV conjugative transfer system protein TraL | - |
| EP178_RS04570 (NgFC428_00797) | - | 787015..787680 (+) | 666 | WP_003704028.1 | conjugal transfer protein TraE | - |
| EP178_RS04575 (NgFC428_00798) | - | 787682..788416 (+) | 735 | WP_003693114.1 | TraK domain-containing protein | - |
| EP178_RS04580 (NgFC428_00799) | - | 788418..789731 (+) | 1314 | WP_003697090.1 | TrbI/VirB10 family protein | - |
| EP178_RS04585 (NgFC428_00800) | - | 789741..790460 (+) | 720 | WP_003693119.1 | DsbC family protein | - |
| EP178_RS04590 (NgFC428_00801) | - | 790457..791038 (+) | 582 | WP_017146802.1 | TraV family lipoprotein | - |
| EP178_RS04595 (NgFC428_00802) | traC | 791048..793624 (+) | 2577 | WP_003693122.1 | type IV secretion system protein TraC | - |
| EP178_RS04600 (NgFC428_00803) | - | 793652..794200 (+) | 549 | WP_003695274.1 | hypothetical protein | - |
| EP178_RS04605 (NgFC428_00804) | - | 794200..794745 (+) | 546 | WP_003704029.1 | S26 family signal peptidase | - |
| EP178_RS04610 (NgFC428_00805) | - | 794754..795410 (+) | 657 | WP_003693128.1 | hypothetical protein | - |
| EP178_RS04615 (NgFC428_00806) | - | 795407..796525 (+) | 1119 | WP_003695266.1 | TraU family protein | - |
| EP178_RS04620 (NgFC428_00807) | trbC | 796540..797292 (+) | 753 | WP_003699946.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| EP178_RS04625 (NgFC428_00808) | - | 797289..798533 (+) | 1245 | WP_003695263.1 | hypothetical protein | - |
| EP178_RS04630 (NgFC428_00809) | traN | 798572..800113 (+) | 1542 | WP_226876101.1 | conjugal transfer protein TraN | - |
| EP178_RS04635 (NgFC428_00810) | - | 800100..800525 (+) | 426 | WP_003693140.1 | hypothetical protein | - |
| EP178_RS04640 (NgFC428_00811) | - | 800537..801313 (+) | 777 | WP_012503632.1 | thioredoxin family protein | - |
| EP178_RS04645 (NgFC428_00812) | - | 801485..802996 (+) | 1512 | WP_041421275.1 | conjugal transfer protein TraH | - |
| EP178_RS04650 (NgFC428_00813) | - | 803003..806005 (+) | 3003 | WP_012503630.1 | conjugal transfer protein TraG N-terminal domain-containing protein | - |
Sequence
Protein
Download Length: 581 a.a. Molecular weight: 63039.83 Da Isoelectric Point: 6.0083
>NTDB_id=69177 EP178_RS04470 WP_003688652.1 766131..767876(+) (recD) [Neisseria gonorrhoeae strain FC428]
MELQTDEFAQAAARAAIRFLERYAGSGNEVLANCTERLFQALQNGHSFIRLSGDEADALSALAPVVGTSAAPLILEGRRL
FLGRMWQLEYDLAAEIKRLAAAGTSAPDAAGARQNLAKWFQGAGSEGQRDAAALALLQFFMVITGGPGTGKTTTVAKLLA
LICGENENLPHIALAAPTGKAAAHMARALHRAINGFDAPEAVRRHLLKLEGQTVHRLLKLSPPKMQAAFDHIRPLPFDVL
IVDEASMLDTALMLQLLKAVKTGARVILLGDENQLPSVGIGAVLSVLSQKTVLDGETHQRLAGFLPEHGFSVSANPPVLA
QNTAHLSFSHRFGDNSGIGCLARAAVSGDEGAWALFDRFPDELEHSECSPNARVERLYRAHKAYWQAVKDGNIEAAYAGI
SDIVVLAAWRQDAEDFNEAYCSYVRRKMNIPEHLAYFAGEPIMIRQNDYALELFNGDIGLIMEDVGRQGSLAAYFADADG
FKKVAVSCLPEFEPAFAMTVHKSQGSEYREVWLLPPSDAPSDEGDDALSGLSKELLYTAITRAREKFVFFGGKKTFCQAV
NTVKVRQTALGSMLERVFSQE
MELQTDEFAQAAARAAIRFLERYAGSGNEVLANCTERLFQALQNGHSFIRLSGDEADALSALAPVVGTSAAPLILEGRRL
FLGRMWQLEYDLAAEIKRLAAAGTSAPDAAGARQNLAKWFQGAGSEGQRDAAALALLQFFMVITGGPGTGKTTTVAKLLA
LICGENENLPHIALAAPTGKAAAHMARALHRAINGFDAPEAVRRHLLKLEGQTVHRLLKLSPPKMQAAFDHIRPLPFDVL
IVDEASMLDTALMLQLLKAVKTGARVILLGDENQLPSVGIGAVLSVLSQKTVLDGETHQRLAGFLPEHGFSVSANPPVLA
QNTAHLSFSHRFGDNSGIGCLARAAVSGDEGAWALFDRFPDELEHSECSPNARVERLYRAHKAYWQAVKDGNIEAAYAGI
SDIVVLAAWRQDAEDFNEAYCSYVRRKMNIPEHLAYFAGEPIMIRQNDYALELFNGDIGLIMEDVGRQGSLAAYFADADG
FKKVAVSCLPEFEPAFAMTVHKSQGSEYREVWLLPPSDAPSDEGDDALSGLSKELLYTAITRAREKFVFFGGKKTFCQAV
NTVKVRQTALGSMLERVFSQE
Nucleotide
Download Length: 1746 bp
>NTDB_id=69177 EP178_RS04470 WP_003688652.1 766131..767876(+) (recD) [Neisseria gonorrhoeae strain FC428]
ATGGAACTGCAGACAGATGAATTTGCCCAAGCGGCGGCAAGGGCGGCAATCCGTTTTTTGGAACGCTATGCGGGTTCGGG
CAACGAAGTGCTTGCAAACTGTACCGAACGCCTGTTTCAGGCATTGCAAAACGGTCATTCGTTTATCCGTTTGAGCGGGG
ACGAGGCTGACGCGCTGTCGGCACTCGCACCCGTGGTCGGAACATCCGCCGCGCCTTTGATTTTGGAAGGCAGAAGGCTG
TTTTTGGGCAGGATGTGGCAGTTGGAATACGATTTGGCTGCCGAAATAAAACGCTTGGCGGCAGCCGGCACGTCCGCCCC
CGACGCGGCAGGCGCGCGGCAAAACCTCGCAAAATGGTTTCAAGGCGCGGGAAGCGAAGGACAGCGCGATGCGGCCGCCT
TGGCACTGTTGCAGTTTTTTATGGTGATTACCGGAGGGCCGGGAACGGGCAAAACGACAACGGTTGCCAAACTGCTGGCA
CTGATTTGCGGTGAAAACGAAAATCTTCCCCATATCGCGCTTGCCGCACCGACGGGCAAAGCGGCGGCACATATGGCGCG
CGCGCTGCACCGTGCAATCAACGGTTTTGACGCGCCGGAGGCCGTCCGCCGCCATTTGCTCAAACTGGAAGGGCAAACCG
TCCACCGACTGCTTAAGCTGAGCCCGCCCAAAATGCAGGCGGCGTTCGACCATATCCGTCCGCTGCCGTTCGACGTGCTG
ATTGTCGATGAAGCCTCCATGTTGGATACCGCATTGATGCTGCAACTTTTGAAAGCGGTCAAAACCGGCGCGCGCGTGAT
TCTGCTGGGCGATGAAAACCAGCTCCCGTCCGTCGGAATCGGGGCGGTGCTGTCGGTTTTGTCGCAAAAAACCGTTTTGG
ACGGAGAAACGCACCAAAGGCTGGCCGGTTTCCTTCCGGAACACGGTTTCAGCGTCAGCGCAAATCCGCCCGTGTTGGCG
CAAAACACCGCCCATCTGTCGTTCAGCCACCGCTTCGGCGACAACAGCGGCATCGGCTGCCTTGCCCGTGCCGCCGTATC
GGGCGATGAAGGGGCGTGGGCATTGTTTGACCGGTTTCCGGACGAACTGGAACATTCGGAATGCAGTCCGAATGCTCGGG
TCGAAAGGTTGTACCGGGCGCACAAAGCCTATTGGCAGGCGGTAAAAGACGGCAATATCGAAGCCGCATACGCAGGCATC
TCGGATATCGTGGTTCTGGCAGCTTGGCGGCAGGATGCGGAAGACTTCAACGAAGCCTATTGCAGCTATGTACGCCGCAA
AATGAACATACCGGAACATTTGGCCTATTTCGCCGGAGAGCCGATTATGATCAGACAGAACGACTACGCGCTTGAGCTGT
TCAACGGCGACATCGGACTGATTATGGAAGATGTCGGACGGCAGGGCAGCCTTGCCGCCTATTTTGCCGATGCGGACGGA
TTTAAAAAGGTAGCGGTAAGCTGCCTGCCCGAATTTGAACCCGCATTCGCCATGACCGTCCACAAAAGCCAAGGTTCGGA
ATATCGGGAAGTCTGGCTGCTGCCGCCTTCCGACGCACCTTCGGACGAAGGGGACGATGCATTGTCCGGATTGAGTAAGG
AGCTGTTATATACCGCCATTACCCGCGCCAGGGAAAAATTCGTATTTTTCGGCGGCAAAAAGACATTTTGTCAGGCGGTA
AACACCGTCAAAGTCCGTCAGACGGCGTTGGGCAGTATGCTTGAGCGGGTATTTTCACAAGAATAA
ATGGAACTGCAGACAGATGAATTTGCCCAAGCGGCGGCAAGGGCGGCAATCCGTTTTTTGGAACGCTATGCGGGTTCGGG
CAACGAAGTGCTTGCAAACTGTACCGAACGCCTGTTTCAGGCATTGCAAAACGGTCATTCGTTTATCCGTTTGAGCGGGG
ACGAGGCTGACGCGCTGTCGGCACTCGCACCCGTGGTCGGAACATCCGCCGCGCCTTTGATTTTGGAAGGCAGAAGGCTG
TTTTTGGGCAGGATGTGGCAGTTGGAATACGATTTGGCTGCCGAAATAAAACGCTTGGCGGCAGCCGGCACGTCCGCCCC
CGACGCGGCAGGCGCGCGGCAAAACCTCGCAAAATGGTTTCAAGGCGCGGGAAGCGAAGGACAGCGCGATGCGGCCGCCT
TGGCACTGTTGCAGTTTTTTATGGTGATTACCGGAGGGCCGGGAACGGGCAAAACGACAACGGTTGCCAAACTGCTGGCA
CTGATTTGCGGTGAAAACGAAAATCTTCCCCATATCGCGCTTGCCGCACCGACGGGCAAAGCGGCGGCACATATGGCGCG
CGCGCTGCACCGTGCAATCAACGGTTTTGACGCGCCGGAGGCCGTCCGCCGCCATTTGCTCAAACTGGAAGGGCAAACCG
TCCACCGACTGCTTAAGCTGAGCCCGCCCAAAATGCAGGCGGCGTTCGACCATATCCGTCCGCTGCCGTTCGACGTGCTG
ATTGTCGATGAAGCCTCCATGTTGGATACCGCATTGATGCTGCAACTTTTGAAAGCGGTCAAAACCGGCGCGCGCGTGAT
TCTGCTGGGCGATGAAAACCAGCTCCCGTCCGTCGGAATCGGGGCGGTGCTGTCGGTTTTGTCGCAAAAAACCGTTTTGG
ACGGAGAAACGCACCAAAGGCTGGCCGGTTTCCTTCCGGAACACGGTTTCAGCGTCAGCGCAAATCCGCCCGTGTTGGCG
CAAAACACCGCCCATCTGTCGTTCAGCCACCGCTTCGGCGACAACAGCGGCATCGGCTGCCTTGCCCGTGCCGCCGTATC
GGGCGATGAAGGGGCGTGGGCATTGTTTGACCGGTTTCCGGACGAACTGGAACATTCGGAATGCAGTCCGAATGCTCGGG
TCGAAAGGTTGTACCGGGCGCACAAAGCCTATTGGCAGGCGGTAAAAGACGGCAATATCGAAGCCGCATACGCAGGCATC
TCGGATATCGTGGTTCTGGCAGCTTGGCGGCAGGATGCGGAAGACTTCAACGAAGCCTATTGCAGCTATGTACGCCGCAA
AATGAACATACCGGAACATTTGGCCTATTTCGCCGGAGAGCCGATTATGATCAGACAGAACGACTACGCGCTTGAGCTGT
TCAACGGCGACATCGGACTGATTATGGAAGATGTCGGACGGCAGGGCAGCCTTGCCGCCTATTTTGCCGATGCGGACGGA
TTTAAAAAGGTAGCGGTAAGCTGCCTGCCCGAATTTGAACCCGCATTCGCCATGACCGTCCACAAAAGCCAAGGTTCGGA
ATATCGGGAAGTCTGGCTGCTGCCGCCTTCCGACGCACCTTCGGACGAAGGGGACGATGCATTGTCCGGATTGAGTAAGG
AGCTGTTATATACCGCCATTACCCGCGCCAGGGAAAAATTCGTATTTTTCGGCGGCAAAAAGACATTTTGTCAGGCGGTA
AACACCGTCAAAGTCCGTCAGACGGCGTTGGGCAGTATGCTTGAGCGGGTATTTTCACAAGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| recD | Neisseria gonorrhoeae strain FA1090 |
99.828 |
100 |
0.998 |