Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   EP178_RS02725 Genome accession   NZ_AP018377
Coordinates   447153..447818 (+) Length   221 a.a.
NCBI ID   WP_047918678.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain FC428     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 442153..452818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EP178_RS02690 (NgFC428_00448) cysT 442428..443257 (-) 830 Protein_451 sulfate ABC transporter permease subunit CysT -
  EP178_RS02695 (NgFC428_00449) - 443443..443775 (+) 333 WP_003687908.1 hypothetical protein -
  EP178_RS02700 (NgFC428_00450) - 444106..444615 (+) 510 WP_003687909.1 isoprenylcysteine carboxyl methyltransferase family protein -
  EP178_RS02710 (NgFC428_00451) - 444847..445428 (-) 582 WP_047923823.1 superoxide dismutase -
  EP178_RS02720 (NgFC428_00452) dnaB 445592..446998 (+) 1407 WP_047917169.1 replicative DNA helicase -
  EP178_RS02725 (NgFC428_00453) pilH 447153..447818 (+) 666 WP_047918678.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  EP178_RS02730 (NgFC428_00454) pilV 447850..448461 (+) 612 WP_050169631.1 type IV pilus modification protein PilV Machinery gene
  EP178_RS02735 (NgFC428_00455) pilJ 448458..449438 (+) 981 WP_010951046.1 PilW family protein Machinery gene
  EP178_RS02740 (NgFC428_00456) pilK 449417..450028 (+) 612 WP_003687918.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  EP178_RS02745 (NgFC428_00457) pilL 450030..450503 (+) 474 WP_025455870.1 PilX family type IV pilin Machinery gene
  EP178_RS02750 (NgFC428_00458) - 450573..450881 (-) 309 WP_010951048.1 AzlD family protein -
  EP178_RS13545 - 450878..451585 (-) 708 Protein_462 AzlC family ABC transporter permease -
  EP178_RS02760 (NgFC428_00460) dut 451751..452203 (+) 453 WP_103195211.1 dUTP diphosphatase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24613.96 Da        Isoelectric Point: 8.6140

>NTDB_id=69167 EP178_RS02725 WP_047918678.1 447153..447818(+) (pilH) [Neisseria gonorrhoeae strain FC428]
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQIANLLRFSRGEAVRLNLPVYICPAQVKKDGTVD
NQCDFGKKEQGMLAFGDKNDNKAYDGDAADVFLRNVVLNDDIKDKRINYTFNHIAFGSSQPTADRVVWTFNQNGTFGYTK
DQHLASTSSFFYSDGYIQIVLTDARAVSDADRKFRSAVVLIDSSGRVEVCRKNDTRAVCKH

Nucleotide


Download         Length: 666 bp        

>NTDB_id=69167 EP178_RS02725 WP_047918678.1 447153..447818(+) (pilH) [Neisseria gonorrhoeae strain FC428]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATTGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGCCCAAGTTAAAAAAGACGGTACGGTCGAC
AACCAATGCGACTTCGGTAAGAAGGAACAGGGGATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCTGCGGATGTTTTTCTCCGTAACGTGGTATTGAATGATGATATCAAGGATAAGCGGATTAATTACACCTTCAATCATA
TCGCTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAA
GACCAGCATCTTGCAAGCACATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAGGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACG
ATACGCGCGCCGTATGCAAACATTAA

Domains

Predicted by InterproScan.

Type II transport protein GspH (GspH)

(44-205)

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

86.878

100

0.869

Multiple sequence alignment