Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   D8S83_RS11000 Genome accession   NZ_AP018349
Coordinates   2163563..2164279 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain GN1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2158563..2169279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D8S83_RS10970 - 2158781..2159407 (+) 627 WP_000522383.1 nitroreductase family protein -
  D8S83_RS10975 - 2159768..2160553 (+) 786 WP_120173205.1 carbon-nitrogen family hydrolase -
  D8S83_RS14625 - 2161152..2161286 (-) 135 WP_001823225.1 delta-lysin family phenol-soluble modulin -
  D8S83_RS10985 - 2161522..2162085 (+) 564 WP_001105715.1 accessory gene regulator AgrB -
  D8S83_RS10990 - 2162087..2162227 (+) 141 WP_001094303.1 cyclic lactone autoinducer peptide -
  D8S83_RS10995 - 2162252..2163544 (+) 1293 WP_172583493.1 GHKL domain-containing protein -
  D8S83_RS11000 agrA 2163563..2164279 (+) 717 WP_000688492.1 LytTR family DNA-binding domain-containing protein Regulator
  D8S83_RS11005 - 2164351..2164458 (+) 108 WP_041204320.1 hypothetical protein -
  D8S83_RS11010 - 2164646..2165605 (-) 960 WP_020977432.1 carbohydrate kinase -
  D8S83_RS11015 - 2165602..2167086 (-) 1485 WP_000141418.1 glycoside hydrolase family 32 protein -
  D8S83_RS11020 - 2167235..2168185 (-) 951 WP_020977433.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=69141 D8S83_RS11000 WP_000688492.1 2163563..2164279(+) (agrA) [Staphylococcus aureus strain GN1]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=69141 D8S83_RS11000 WP_000688492.1 2163563..2164279(+) (agrA) [Staphylococcus aureus strain GN1]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment