Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   M8969_RS11325 Genome accession   NZ_CP097593
Coordinates   2364191..2364847 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain UA0229     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2359191..2369847
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8969_RS11305 spxH 2359430..2360332 (+) 903 WP_032874464.1 protease adaptor protein SpxH -
  M8969_RS11310 - 2360618..2360785 (+) 168 WP_032874462.1 hypothetical protein -
  M8969_RS11315 pepF 2360823..2362652 (-) 1830 WP_087920792.1 oligoendopeptidase F Regulator
  M8969_RS11320 - 2362880..2364040 (-) 1161 WP_032874460.1 competence protein CoiA family protein -
  M8969_RS11325 mecA 2364191..2364847 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  M8969_RS11335 - 2365123..2365779 (+) 657 WP_032874459.1 TerC family protein -
  M8969_RS11340 spx 2365836..2366231 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  M8969_RS11345 - 2366410..2366988 (-) 579 WP_032874457.1 GNAT family N-acetyltransferase -
  M8969_RS11350 - 2367106..2368293 (-) 1188 WP_079891125.1 putative glycoside hydrolase -
  M8969_RS11355 oppF 2368400..2369317 (-) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=690859 M8969_RS11325 WP_003155032.1 2364191..2364847(-) (mecA) [Bacillus velezensis strain UA0229]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=690859 M8969_RS11325 WP_003155032.1 2364191..2364847(-) (mecA) [Bacillus velezensis strain UA0229]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAGA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895