Detailed information    

insolico Bioinformatically predicted

Overview

Name   spo0A   Type   Regulator
Locus tag   M8962_RS12835 Genome accession   NZ_CP097591
Coordinates   2631349..2632149 (+) Length   266 a.a.
NCBI ID   WP_003153177.1    Uniprot ID   I2C7K5
Organism   Bacillus velezensis strain UA0188     
Function   activation and repression of comK; repression of rok; repression of abrB (predicted from homology)   
Competence regulation

Genomic Context

Location: 2626349..2637149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8962_RS12815 - 2626471..2627316 (+) 846 WP_007612503.1 TlyA family RNA methyltransferase -
  M8962_RS12820 argR 2627413..2627862 (+) 450 WP_003153173.1 transcriptional regulator ArgR -
  M8962_RS12825 recN 2627894..2629624 (+) 1731 WP_012117962.1 DNA repair protein RecN Machinery gene
  M8962_RS12830 spoIVB 2629788..2631068 (+) 1281 WP_012117961.1 SpoIVB peptidase -
  M8962_RS12835 spo0A 2631349..2632149 (+) 801 WP_003153177.1 sporulation transcription factor Spo0A Regulator
  M8962_RS12840 alr 2632298..2633479 (-) 1182 WP_012117960.1 alanine racemase -
  M8962_RS12845 - 2633656..2633868 (-) 213 WP_003153181.1 spore germination protein -
  M8962_RS12850 - 2633994..2634206 (-) 213 WP_007408362.1 spore germination protein -
  M8962_RS12855 - 2634334..2635452 (-) 1119 WP_015240192.1 NADH-dependent flavin oxidoreductase -
  M8962_RS12860 - 2635546..2635683 (-) 138 WP_014470646.1 hypothetical protein -
  M8962_RS12865 - 2635980..2636612 (-) 633 WP_007408365.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 266 a.a.        Molecular weight: 29630.11 Da        Isoelectric Point: 6.1630

>NTDB_id=690800 M8962_RS12835 WP_003153177.1 2631349..2632149(+) (spo0A) [Bacillus velezensis strain UA0188]
MEKIKVCVADDNRELVSLLSEYIEGQDDMEVIGVAYNGQECLSLFKDKNPDVLVLDIIMPHLDGLAVLERLRESELEKQP
NVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLVGHIRQVSGNVSSVTHRAPSAQSSIIRSQPEPKRKNLDASITSII
HEIGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVS
MTKAKPTNSEFIAMVADKLRLEHKAS

Nucleotide


Download         Length: 801 bp        

>NTDB_id=690800 M8962_RS12835 WP_003153177.1 2631349..2632149(+) (spo0A) [Bacillus velezensis strain UA0188]
GTGGAGAAAATTAAAGTTTGTGTTGCTGATGATAATCGAGAGCTTGTAAGCCTGTTGAGTGAATATATAGAGGGACAGGA
TGATATGGAAGTGATCGGCGTTGCTTATAACGGACAGGAATGTCTTTCTTTGTTTAAAGATAAGAATCCAGATGTGCTCG
TTTTAGACATTATCATGCCGCATCTGGACGGACTTGCGGTTTTGGAGCGTCTGCGGGAATCAGAGCTCGAGAAGCAGCCG
AACGTCATCATGCTGACGGCATTCGGTCAGGAAGACGTTACGAAAAAAGCCGTCGATTTAGGCGCGTCCTATTTCATCCT
GAAGCCGTTTGATATGGAAAACCTTGTCGGCCATATCCGCCAGGTAAGCGGAAATGTCAGCAGTGTCACACACCGTGCGC
CGTCCGCGCAAAGCAGTATTATCCGCAGCCAGCCGGAACCGAAGCGGAAAAATCTCGATGCCAGCATTACAAGCATTATC
CATGAGATCGGTGTGCCTGCCCATATCAAAGGCTATCTTTATTTGCGTGAAGCCATTTCCATGGTGTATAACGATATTGA
ACTCCTCGGCAGCATCACAAAAGTCCTTTATCCCGACATCGCCAAAAAATTCAACACGACTGCAAGCCGTGTAGAACGGG
CCATCCGCCACGCCATTGAAGTCGCATGGAGCAGGGGAAATATTGATTCCATTTCTTCACTGTTCGGATATACGGTAAGC
ATGACAAAAGCAAAGCCAACCAACTCGGAATTCATCGCGATGGTTGCTGACAAGCTGAGATTAGAGCATAAAGCTTCGTA
A

Domains

Predicted by InterproScan.

Sporulation initiation factor Spo0A C terminal (Spo0A_C)

(156-259)

Response regulator receiver domain (Response_reg)

(6-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C7K5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  spo0A Bacillus subtilis subsp. subtilis str. 168

96.629

100

0.97