Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   M8964_RS14325 Genome accession   NZ_CP097585
Coordinates   2919682..2920338 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain UA1365     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2914682..2925338
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8964_RS14305 spxH 2914921..2915823 (+) 903 WP_012117287.1 protease adaptor protein SpxH -
  M8964_RS14310 - 2916109..2916276 (+) 168 WP_003155026.1 hypothetical protein -
  M8964_RS14315 pepF 2916314..2918143 (-) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  M8964_RS14320 - 2918371..2919531 (-) 1161 WP_012117286.1 competence protein CoiA family protein -
  M8964_RS14325 mecA 2919682..2920338 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  M8964_RS14335 - 2920614..2921270 (+) 657 WP_012117285.1 TerC family protein -
  M8964_RS14340 spx 2921328..2921723 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  M8964_RS14345 - 2921902..2922480 (-) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  M8964_RS14350 - 2922589..2923785 (-) 1197 WP_012117284.1 putative glycoside hydrolase -
  M8964_RS14355 oppF 2923892..2924809 (-) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=690426 M8964_RS14325 WP_003155032.1 2919682..2920338(-) (mecA) [Bacillus velezensis strain UA1365]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=690426 M8964_RS14325 WP_003155032.1 2919682..2920338(-) (mecA) [Bacillus velezensis strain UA1365]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
GGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895