Detailed information NTG0690325

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: M8286_RS02470
• Genome accession: NZ_CP097577
• Coordinates: 488250..490469 (-)
• Length: 739 a.a.
• NCBI ID: WP_275601376.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 3112
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 483250..495469

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M8286_RS02455 (M8286_02465)	-	485780..487291 (+)	1512	WP_358638961.1	IS1182 family transposase	-
M8286_RS02460 (M8286_02470)	-	487240..487548 (-)	309	WP_002938710.1	DUF1827 family protein	-
M8286_RS02465 (M8286_02475)	-	487603..488064 (-)	462	WP_275601375.1	NUDIX hydrolase	-
M8286_RS02470 (M8286_02480)	clpE	488250..490469 (-)	2220	WP_275601376.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
M8286_RS02475 (M8286_02485)	-	490692..490922 (+)	231	WP_002938704.1	DUF1797 family protein	-
M8286_RS02480 (M8286_02490)	-	491047..491736 (+)	690	WP_002938702.1	amino acid ABC transporter permease	-
M8286_RS02485 (M8286_02495)	-	491729..492463 (+)	735	WP_002943067.1	amino acid ABC transporter ATP-binding protein	-
M8286_RS02490 (M8286_02500)	-	492697..493545 (+)	849	WP_275601377.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
M8286_RS02495 (M8286_02505)	-	494974..495273 (+)	300	WP_275601378.1	DNA repair protein	-

Sequence

Protein

• Length: 739 a.a.
• Molecular weight: 82234.53 Da
• Isoelectric Point: 5.2782

>NTDB_id=690325 M8286_RS02470 WP_275601376.1 488250..490469(-) (clpE) [Streptococcus suis strain 3112]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGGHNGRGGQTQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGVGKT
AVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGDGNM
DAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIEAAA
VLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQKATI
SEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGSFLF
VGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVEKAH
PDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDGIIE
FQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAEKDL
RAVMSSKGTIQIKAQTKTK

Nucleotide

• Length: 2220 bp

>NTDB_id=690325 M8286_RS02470 WP_275601376.1 488250..490469(-) (clpE) [Streptococcus suis strain 3112]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAACAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCTATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTCTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACTCAAGCCGGTGGTGGGCATAATGGACGTGGTGGACAGACCCAACCCCAACAACCAAATGGGCT
CCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCGATCAAGAAA
TTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAATAACCCTGTTCTTATCGGTGAGCCTGGAGTAGGTAAAACA
GCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTGCCACAGAAATTACGAGACAAGGAAGTCATTCGTCT
GGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGCGGACAATTTGAAGAACGCATGCAAAAACTCATGGAAGAAATCC
GTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGTTCTGCAGGCGATGGCAACATG
GATGCTGGCAATATCCTCAAACCAGCCCTTGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAACGAATACCG
TATTATCGAAAAAGATGCCGCCCTAGAGCGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAGAAACCATTA
CCATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCAGCTATCGAAGCTGCCGCA
GTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAGGCTATTGACCTTCTGGATGAAGCTGGTTCAAAAAT
GAATTTGACCCTCAACTTTATTGATCCAAAAGAAATTGACCAACGCCTGATTGATGCCGAAAATCGTAAAGCACAAGCTA
CACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAGGCAACTATC
AGCGAGGAAGATATTCCACTCATTACTGAGAAAGAAATTGAGGCCATTGTTGAGCAAAAAACAAATATCCCAGTTGGTGA
TTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAGATGAAGCAG
TTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCAATTGGATCCTTCCTCTTT
GTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCGGACAGCATGAT
CCGCTTCGATATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATGTAGGCTATG
AGGAGGCTGGACAATTGACTGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTCGAAAAAGCCCAT
CCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGGCGTCTGACAGATGGACAAGGTCGGACAGTCAGCTTCAA
AGATACCATCATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGGCTATGGAAG
GGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGCATTATTGAG
TTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTGAACAAACGCCTTTCTCACAA
TGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGGGAGCTCGTC
CACTACGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAAAAAGACCTA
CGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (644-718)

• AAA domain (Cdc48 subfamily) (AAA_2) (473-636)

• ATPase family associated with various cellular activities (AAA) (AAA) (150-269)

• AAA lid domain (AAA_lid_9) (288-386)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.024	100	0.834
clpE	Streptococcus pneumoniae D39	82.024	100	0.834
clpE	Streptococcus pneumoniae R6	82.024	100	0.834
clpE	Streptococcus pneumoniae TIGR4	82.024	100	0.834
clpE	Streptococcus mutans UA159	81.818	100	0.828
clpC	Lactococcus lactis subsp. cremoris KW2	77.732	97.835	0.76
clpC	Bacillus subtilis subsp. subtilis str. 168	51.574	90.257	0.465
clpC	Streptococcus thermophilus LMD-9	47.352	86.874	0.411
clpC	Streptococcus mutans UA159	48.558	84.438	0.41
clpC	Streptococcus thermophilus LMG 18311	47.04	86.874	0.409
clpC	Streptococcus pneumoniae Rx1	47.84	84.574	0.405
clpC	Streptococcus pneumoniae D39	47.84	84.574	0.405
clpC	Streptococcus pneumoniae TIGR4	47.84	84.574	0.405
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.815	84.98	0.398