Detailed information NTG0690209

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: M8789_RS13410
• Genome accession: NZ_CP097571
• Coordinates: 2692999..2693886 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain V40
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2687999..2698886

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M8789_RS13380 (M8789_13380)	-	2688002..2688094 (+)	93	WP_010956583.1	hypothetical protein	-
M8789_RS13385 (M8789_13385)	-	2688202..2688699 (-)	498	WP_001065267.1	glutathione peroxidase	-
M8789_RS13390 (M8789_13390)	-	2688709..2688969 (-)	261	WP_014532715.1	hypothetical protein	-
M8789_RS13395 (M8789_13395)	-	2689351..2689464 (-)	114	WP_072357681.1	hypothetical protein	-
M8789_RS13400 (M8789_13400)	-	2690139..2692139 (-)	2001	WP_000776732.1	ABC transporter permease	-
M8789_RS13405 (M8789_13405)	-	2692136..2692891 (-)	756	WP_044122909.1	ABC transporter ATP-binding protein	-
M8789_RS13410 (M8789_13410)	braS	2692999..2693886 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
M8789_RS13415 (M8789_13415)	braR	2693897..2694562 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
M8789_RS13420 (M8789_13420)	-	2694588..2694788 (-)	201	WP_000604727.1	hypothetical protein	-
M8789_RS13425 (M8789_13425)	-	2694986..2696410 (+)	1425	WP_000948997.1	alkaline phosphatase	-
M8789_RS13875	-	2696470..2696571 (-)	102	WP_000731972.1	SE2200 family small protein	-
M8789_RS13435 (M8789_13435)	-	2696693..2697148 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
M8789_RS13440 (M8789_13440)	-	2697393..2698154 (-)	762	WP_000323443.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=690209 M8789_RS13410 WP_000143420.1 2692999..2693886(-) (braS) [Staphylococcus aureus strain V40]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=690209 M8789_RS13410 WP_000143420.1 2692999..2693886(-) (braS) [Staphylococcus aureus strain V40]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993