Detailed information NTG0690204

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: M8789_RS09630
• Genome accession: NZ_CP097571
• Coordinates: 1966652..1967695 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain V40
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1961652..1972695

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M8789_RS09600 (M8789_09600)	-	1962073..1963329 (-)	1257	WP_001793428.1	aminopeptidase	-
M8789_RS09605 (M8789_09605)	-	1963332..1963532 (-)	201	WP_000180462.1	DUF1128 family protein	-
M8789_RS09610 (M8789_09610)	-	1963679..1964143 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
M8789_RS09615 (M8789_09615)	-	1964150..1964425 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
M8789_RS09620 (M8789_09620)	-	1964703..1965920 (+)	1218	WP_000037088.1	YihY/virulence factor BrkB family protein	-
M8789_RS09625 (M8789_09625)	vraR	1966033..1966662 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
M8789_RS09630 (M8789_09630)	vraS	1966652..1967695 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
M8789_RS09635 (M8789_09635)	liaF	1967692..1968393 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
M8789_RS09640 (M8789_09640)	-	1968408..1968794 (-)	387	WP_001110175.1	hypothetical protein	-
M8789_RS09645 (M8789_09645)	map	1969011..1969769 (-)	759	WP_250164280.1	type I methionyl aminopeptidase	-
M8789_RS09650 (M8789_09650)	-	1970353..1971339 (+)	987	WP_000999713.1	FUSC family protein	-
M8789_RS09655 (M8789_09655)	-	1971528..1971941 (-)	414	WP_078064660.1	hypothetical protein	-
M8789_RS09660 (M8789_09660)	-	1971970..1972082 (-)	113	Protein_1866	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=690204 M8789_RS09630 WP_001017131.1 1966652..1967695(-) (vraS) [Staphylococcus aureus strain V40]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=690204 M8789_RS09630 WP_001017131.1 1966652..1967695(-) (vraS) [Staphylococcus aureus strain V40]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATTTTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1