Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   M8789_RS07760 Genome accession   NZ_CP097571
Coordinates   1606882..1607856 (-) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain V40     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1601882..1612856
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8789_RS07720 (M8789_07720) gcvT 1602383..1603474 (-) 1092 WP_000093354.1 glycine cleavage system aminomethyltransferase GcvT -
  M8789_RS07725 (M8789_07725) - 1603633..1604157 (-) 525 WP_001015120.1 shikimate kinase -
  M8789_RS07730 (M8789_07730) - 1604147..1604293 (-) 147 WP_001789879.1 hypothetical protein -
  M8789_RS07735 (M8789_07735) comGF 1604390..1604887 (-) 498 WP_001825340.1 competence type IV pilus minor pilin ComGF Machinery gene
  M8789_RS07740 (M8789_07740) comGE 1604805..1605104 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  M8789_RS07745 (M8789_07745) comGD 1605091..1605537 (-) 447 WP_072357807.1 competence type IV pilus minor pilin ComGD Machinery gene
  M8789_RS07750 (M8789_07750) comGC 1605515..1605826 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  M8789_RS07755 (M8789_07755) comGB 1605840..1606910 (-) 1071 WP_000776413.1 competence type IV pilus assembly protein ComGB Machinery gene
  M8789_RS07760 (M8789_07760) comGA 1606882..1607856 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  M8789_RS07765 (M8789_07765) - 1607908..1608531 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  M8789_RS07770 (M8789_07770) - 1608528..1608857 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  M8789_RS07775 (M8789_07775) - 1608857..1609843 (-) 987 WP_000161315.1 ROK family glucokinase -
  M8789_RS07780 (M8789_07780) - 1609840..1610043 (-) 204 WP_000087561.1 YqgQ family protein -
  M8789_RS07785 (M8789_07785) - 1610024..1611487 (-) 1464 WP_044122531.1 rhomboid family protein -
  M8789_RS07790 (M8789_07790) - 1611499..1612038 (-) 540 WP_000164552.1 5-formyltetrahydrofolate cyclo-ligase -
  M8789_RS07795 (M8789_07795) rpmG 1612247..1612396 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=690192 M8789_RS07760 WP_000697220.1 1606882..1607856(-) (comGA) [Staphylococcus aureus strain V40]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=690192 M8789_RS07760 WP_000697220.1 1606882..1607856(-) (comGA) [Staphylococcus aureus strain V40]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTAATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGACCTACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAAGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1