Detailed information NTG0068984

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: SPYKS030_RS02145
• Genome accession: NZ_AP018337
• Coordinates: 405807..406532 (+)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain KS030
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 400807..411532

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYKS030_RS02115 (SPYKS030_03620)	-	400986..402446 (+)	1461	WP_032462143.1	NCS2 family permease	-
SPYKS030_RS02120 (SPYKS030_03630)	tsaE	402600..403061 (+)	462	WP_002983367.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
SPYKS030_RS02125 (SPYKS030_03640)	-	403036..403560 (+)	525	WP_002983369.1	GNAT family N-acetyltransferase	-
SPYKS030_RS02130 (SPYKS030_03650)	brpA	403569..404852 (+)	1284	WP_002994335.1	biofilm formation/cell division transcriptional regulator BrpA	-
SPYKS030_RS02135 (SPYKS030_03660)	-	404963..405319 (-)	357	WP_002988657.1	hypothetical protein	-
SPYKS030_RS02140 (SPYKS030_03670)	-	405316..405735 (-)	420	WP_002983376.1	HIT family protein	-
SPYKS030_RS02145 (SPYKS030_03680)	pptA	405807..406532 (+)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
SPYKS030_RS02150 (SPYKS030_03690)	-	406535..407569 (+)	1035	WP_010922583.1	ABC transporter permease	-
SPYKS030_RS02155 (SPYKS030_03700)	ccrZ	407633..408424 (+)	792	WP_002983385.1	cell cycle regulator CcrZ	-
SPYKS030_RS02160 (SPYKS030_03710)	trmB	408424..409059 (+)	636	WP_120164360.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
SPYKS030_RS02170 (SPYKS030_03720)	rimP	409318..409854 (+)	537	WP_011054929.1	ribosome maturation factor RimP	-
SPYKS030_RS02175 (SPYKS030_03730)	nusA	410029..411186 (+)	1158	WP_002994325.1	transcription termination factor NusA	-
SPYKS030_RS02180 (SPYKS030_03740)	rnpM	411202..411498 (+)	297	WP_002983486.1	RNase P modulator RnpM	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=68984 SPYKS030_RS02145 WP_002983379.1 405807..406532(+) (pptA) [Streptococcus pyogenes strain KS030]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=68984 SPYKS030_RS02145 WP_002983379.1 405807..406532(+) (pptA) [Streptococcus pyogenes strain KS030]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714