Detailed information NTG0689718

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: OTU45_RS10435
• Genome accession: NZ_CP113114
• Coordinates: 2036785..2037696 (-)
• Length: 303 a.a.
• NCBI ID: WP_000904830.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain NP1
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 2031785..2042696

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OTU45_RS10410 (OTU45_10410)	rsmA	2032115..2032987 (-)	873	WP_050117944.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
OTU45_RS10415 (OTU45_10415)	-	2033118..2033426 (-)	309	WP_000333257.1	hypothetical protein	-
OTU45_RS10420 (OTU45_10420)	-	2033419..2034060 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
OTU45_RS10425 (OTU45_10425)	-	2034062..2036092 (-)	2031	WP_000825251.1	bacteriocin-associated integral membrane family protein	-
OTU45_RS10430 (OTU45_10430)	-	2036169..2036465 (-)	297	WP_000815394.1	lactococcin 972 family bacteriocin	-
OTU45_RS10435 (OTU45_10435)	comR	2036785..2037696 (-)	912	WP_000904830.1	helix-turn-helix domain-containing protein	Regulator
OTU45_RS10440 (OTU45_10440)	rnmV	2037768..2038328 (-)	561	WP_000660013.1	ribonuclease M5	-
OTU45_RS10445 (OTU45_10445)	-	2038328..2039101 (-)	774	WP_000575616.1	TatD family hydrolase	-
OTU45_RS10450 (OTU45_10450)	-	2039406..2040125 (-)	720	Protein_2055	DUF1542 domain-containing protein	-
OTU45_RS10455 (OTU45_10455)	rpmH	2040334..2040468 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
OTU45_RS10460 (OTU45_10460)	-	2040613..2041827 (-)	1215	WP_000666472.1	pyridoxal phosphate-dependent aminotransferase	-
OTU45_RS10465 (OTU45_10465)	-	2041983..2042276 (-)	294	WP_000977367.1	hypothetical protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35425.73 Da
• Isoelectric Point: 4.5727

>NTDB_id=689718 OTU45_RS10435 WP_000904830.1 2036785..2037696(-) (comR) [Streptococcus pneumoniae strain NP1]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIEDLFYEQLPNEEKVWFEATRATIDVIRSGRPEYGETVLDDYFKTIYDKELFLINELEV
INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIASEYLFALSNTLFSGLACLDNLSSYDSLGAYIFSLNHIMEK
TQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQKSKLFADIIENSYLVTMLEKQWQEDLKKYL

Nucleotide

• Length: 912 bp

>NTDB_id=689718 OTU45_RS10435 WP_000904830.1 2036785..2037696(-) (comR) [Streptococcus pneumoniae strain NP1]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATAGAGGATTTATTTTA
TGAGCAACTTCCTAATGAGGAAAAAGTATGGTTTGAAGCTACTAGAGCAACGATAGATGTTATTCGAAGTGGACGACCAG
AATACGGGGAAACCGTACTGGACGATTATTTTAAAACAATTTATGATAAGGAATTGTTTTTGATAAATGAATTAGAAGTT
ATCAACTTATATTTTGCTATAGTGCTTACAAAGATAAAACAAGGTCAAAATCAGATTGAAGAAATTAACAGAATTCATTC
GTTTTTAGTTCGTTTGACAAATCATGTAGAATTAATTGCATCAGAATATCTGTTTGCTTTAAGTAACACTTTGTTTTCGG
GTCTAGCCTGTTTGGATAACTTGTCGTCTTATGATTCACTAGGAGCTTATATCTTTAGCCTTAATCATATAATGGAAAAA
ACACAAGATTTTCAGAAGAAACCAATTATATTAATGTTGGAGTGGAAATTATCTCTAATAATAAACAATGATTATGTTTC
TGCCGAACAGTTCTATCAGAAATCGAAGCTATTTGCTGATATAATAGAAAATTCTTATTTAGTTACTATGTTAGAAAAAC
AATGGCAAGAAGATTTAAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-295)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	39.189	97.69	0.383
comR	Streptococcus pyogenes MGAS8232	37.5	100	0.376
comR	Streptococcus suis P1/7	37.966	97.36	0.37
comR	Streptococcus suis 05ZYH33	37.966	97.36	0.37