Detailed information NTG0689060

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: M5C55_RS14140
• Genome accession: NZ_CP097359
• Coordinates: 2894308..2895471 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain H208
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2889308..2900471

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M5C55_RS14110 (M5C55_14110)	-	2889572..2889991 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
M5C55_RS14115 (M5C55_14115)	comFC	2890065..2890754 (-)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
M5C55_RS14120 (M5C55_14120)	-	2890760..2891044 (-)	285	WP_003151389.1	competence protein ComFB	-
M5C55_RS14125 (M5C55_14125)	comFA	2891102..2892487 (-)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
M5C55_RS14130 (M5C55_14130)	-	2892596..2893444 (-)	849	WP_032876160.1	DegV family protein	-
M5C55_RS14135 (M5C55_14135)	degU	2893542..2894231 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
M5C55_RS14140 (M5C55_14140)	degS	2894308..2895471 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
M5C55_RS14145 (M5C55_14145)	-	2895694..2896341 (+)	648	WP_007614107.1	YigZ family protein	-
M5C55_RS14150 (M5C55_14150)	-	2896346..2897527 (+)	1182	WP_032876157.1	LCP family protein	-
M5C55_RS14155 (M5C55_14155)	-	2897626..2898702 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
M5C55_RS14160 (M5C55_14160)	-	2898835..2900031 (-)	1197	WP_032876154.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=689060 M5C55_RS14140 WP_007407484.1 2894308..2895471(-) (degS) [Bacillus velezensis strain H208]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=689060 M5C55_RS14140 WP_007407484.1 2894308..2895471(-) (degS) [Bacillus velezensis strain H208]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951