Detailed information
Bioinformatically predicted
Overview
| Name | pilA | Type | Machinery gene |
| Locus tag | MCB1EB_RS10820 | Genome accession | NZ_AP018150 |
| Coordinates | 2559442..2560467 (+) | Length | 341 a.a. |
| NCBI ID | WP_045364349.1 | Uniprot ID | - |
| Organism | Mycoavidus cysteinexigens strain B1EB | ||
| Function | assembly of type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 2559442..2605588 | 2559442..2560467 | within | 0 |
Gene organization within MGE regions
Location: 2559442..2605588
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MCB1EB_RS10820 (MCB1EB_2114) | pilA | 2559442..2560467 (+) | 1026 | WP_045364349.1 | signal recognition particle-docking protein FtsY | Machinery gene |
| MCB1EB_RS10825 (MCB1EB_2115) | - | 2560483..2561181 (-) | 699 | WP_045364346.1 | fumarylacetoacetate hydrolase family protein | - |
| MCB1EB_RS10830 (MCB1EB_2116) | - | 2561479..2561919 (-) | 441 | WP_045364344.1 | DUF892 family protein | - |
| MCB1EB_RS10835 (MCB1EB_2117) | - | 2562139..2562537 (-) | 399 | WP_045364341.1 | hypothetical protein | - |
| MCB1EB_RS10840 (MCB1EB_2118) | - | 2562931..2563431 (+) | 501 | WP_052393941.1 | Hsp20/alpha crystallin family protein | - |
| MCB1EB_RS10845 (MCB1EB_2119) | rpoH | 2563723..2564637 (+) | 915 | WP_045364338.1 | RNA polymerase sigma factor RpoH | - |
| MCB1EB_RS10850 (MCB1EB_2120) | - | 2565197..2566330 (+) | 1134 | WP_045364336.1 | hypothetical protein | - |
| MCB1EB_RS10855 (MCB1EB_2121) | clpA | 2566501..2568798 (-) | 2298 | WP_045364333.1 | ATP-dependent Clp protease ATP-binding subunit ClpA | - |
| MCB1EB_RS10860 (MCB1EB_2122) | clpS | 2568795..2569109 (-) | 315 | WP_026921564.1 | ATP-dependent Clp protease adapter ClpS | - |
| MCB1EB_RS10865 (MCB1EB_2123) | nagA | 2569235..2570275 (-) | 1041 | WP_045364329.1 | N-acetylglucosamine-6-phosphate deacetylase | - |
| MCB1EB_RS10870 (MCB1EB_2124) | - | 2570366..2571007 (-) | 642 | WP_045364326.1 | SCO family protein | - |
| MCB1EB_RS10875 (MCB1EB_2125) | cyoE | 2570979..2571887 (-) | 909 | WP_045364322.1 | heme o synthase | - |
| MCB1EB_RS10880 (MCB1EB_2126) | - | 2571892..2572980 (-) | 1089 | WP_045364319.1 | heme A synthase | - |
| MCB1EB_RS10885 (MCB1EB_2127) | - | 2573000..2573590 (-) | 591 | WP_045364316.1 | cytochrome c oxidase subunit I | - |
| MCB1EB_RS10890 (MCB1EB_2128) | - | 2573659..2574369 (-) | 711 | WP_045364314.1 | SURF1 family protein | - |
| MCB1EB_RS10895 | - | 2574462..2574671 (+) | 210 | WP_026921571.1 | twin transmembrane helix small protein | - |
| MCB1EB_RS10900 (MCB1EB_2130) | - | 2574737..2575594 (-) | 858 | WP_045364311.1 | cytochrome c oxidase subunit 3 | - |
| MCB1EB_RS10905 (MCB1EB_2131) | ctaD | 2575687..2577282 (-) | 1596 | WP_026921573.1 | cytochrome c oxidase subunit I | - |
| MCB1EB_RS10910 (MCB1EB_2132) | coxB | 2577453..2578598 (-) | 1146 | Protein_2166 | cytochrome c oxidase subunit II | - |
| MCB1EB_RS10915 (MCB1EB_2133) | - | 2578689..2579690 (-) | 1002 | WP_045364308.1 | methyltransferase domain-containing protein | - |
| MCB1EB_RS10920 (MCB1EB_2134) | - | 2579788..2580579 (+) | 792 | WP_232034111.1 | ComF family protein | - |
| MCB1EB_RS10925 (MCB1EB_2135) | trmL | 2580656..2581126 (+) | 471 | WP_045364305.1 | tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL | - |
| MCB1EB_RS10930 (MCB1EB_2136) | - | 2581175..2582191 (-) | 1017 | WP_045364303.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| MCB1EB_RS10935 (MCB1EB_2137) | secB | 2582286..2582843 (-) | 558 | WP_081678016.1 | protein-export chaperone SecB | - |
| MCB1EB_RS10940 (MCB1EB_2138) | grxC | 2582888..2583151 (-) | 264 | WP_026921578.1 | glutaredoxin 3 | - |
| MCB1EB_RS10945 (MCB1EB_2139) | - | 2583160..2583567 (-) | 408 | WP_026921579.1 | rhodanese-like domain-containing protein | - |
| MCB1EB_RS10950 (MCB1EB_2140) | gpmA | 2583715..2584461 (+) | 747 | WP_045364300.1 | 2,3-diphosphoglycerate-dependent phosphoglycerate mutase | - |
| MCB1EB_RS10955 (MCB1EB_2141) | - | 2584542..2586047 (+) | 1506 | WP_045364297.1 | S41 family peptidase | - |
| MCB1EB_RS10960 (MCB1EB_2142) | - | 2586072..2586824 (+) | 753 | WP_045364294.1 | HesA/MoeB/ThiF family protein | - |
| MCB1EB_RS10965 (MCB1EB_2143) | - | 2587010..2587237 (+) | 228 | WP_026921581.1 | cold-shock protein | - |
| MCB1EB_RS10970 (MCB1EB_2144) | icd | 2587323..2588579 (-) | 1257 | WP_045364291.1 | NADP-dependent isocitrate dehydrogenase | - |
| MCB1EB_RS10975 (MCB1EB_2145) | - | 2588801..2589043 (+) | 243 | WP_045364288.1 | hypothetical protein | - |
| MCB1EB_RS10980 (MCB1EB_2146) | - | 2589237..2589728 (+) | 492 | WP_232034112.1 | DUF192 domain-containing protein | - |
| MCB1EB_RS10985 (MCB1EB_2147) | - | 2589794..2590375 (-) | 582 | WP_045364285.1 | superoxide dismutase | - |
| MCB1EB_RS10990 (MCB1EB_2148) | xseA | 2590522..2591766 (-) | 1245 | WP_045364282.1 | exodeoxyribonuclease VII large subunit | - |
| MCB1EB_RS10995 (MCB1EB_2149) | lpxK | 2592031..2593053 (+) | 1023 | WP_045364279.1 | tetraacyldisaccharide 4'-kinase | - |
| MCB1EB_RS11000 (MCB1EB_2150) | - | 2593034..2593237 (+) | 204 | WP_026921587.1 | Trm112 family protein | - |
| MCB1EB_RS11005 (MCB1EB_2151) | kdsB | 2593255..2594100 (+) | 846 | WP_045364276.1 | 3-deoxy-manno-octulosonate cytidylyltransferase | - |
| MCB1EB_RS11010 (MCB1EB_2152) | adk | 2594180..2594857 (+) | 678 | WP_026921589.1 | adenylate kinase | - |
| MCB1EB_RS11015 (MCB1EB_2153) | murJ | 2594893..2596446 (-) | 1554 | WP_045364272.1 | murein biosynthesis integral membrane protein MurJ | - |
| MCB1EB_RS11020 (MCB1EB_2154) | rpsT | 2596608..2596892 (+) | 285 | WP_026921591.1 | 30S ribosomal protein S20 | - |
| MCB1EB_RS11025 (MCB1EB_2155) | - | 2597032..2597337 (-) | 306 | Protein_2189 | DUF3579 domain-containing protein | - |
| MCB1EB_RS11030 (MCB1EB_2156) | argF | 2597528..2598457 (+) | 930 | WP_045364266.1 | ornithine carbamoyltransferase | - |
| MCB1EB_RS11035 (MCB1EB_2157) | - | 2598476..2599705 (+) | 1230 | WP_045364263.1 | argininosuccinate synthase | - |
| MCB1EB_RS11040 (MCB1EB_2158) | murB | 2599713..2600738 (-) | 1026 | WP_045364261.1 | UDP-N-acetylmuramate dehydrogenase | - |
| MCB1EB_RS11045 (MCB1EB_2159) | - | 2600919..2601404 (+) | 486 | WP_026921595.1 | YajQ family cyclic di-GMP-binding protein | - |
| MCB1EB_RS11050 (MCB1EB_2160) | plsY | 2601431..2602060 (-) | 630 | WP_026921596.1 | glycerol-3-phosphate 1-O-acyltransferase PlsY | - |
| MCB1EB_RS12465 | - | 2602159..2602251 (-) | 93 | Protein_2195 | RNA-guided endonuclease TnpB family protein | - |
| MCB1EB_RS11060 (MCB1EB_2161) | - | 2602351..2604012 (+) | 1662 | WP_232034113.1 | class I adenylate-forming enzyme family protein | - |
| MCB1EB_RS11065 (MCB1EB_2162) | ppa | 2603996..2604523 (-) | 528 | WP_026921599.1 | inorganic diphosphatase | - |
| MCB1EB_RS11070 (MCB1EB_2163) | xerD | 2604650..2605588 (-) | 939 | WP_045364255.1 | site-specific tyrosine recombinase XerD | - |
Sequence
Protein
Download Length: 341 a.a. Molecular weight: 37247.81 Da Isoelectric Point: 7.1479
>NTDB_id=68886 MCB1EB_RS10820 WP_045364349.1 2559442..2560467(+) (pilA) [Mycoavidus cysteinexigens strain B1EB]
MFSFFKKLHKSSTSTSELTEAENKSKNDTQDKNPPAPELTPDRPTSWVKRLKSGLAKTRNNFTNLFTNVKIDEDFFEELE
AALLMADTGLEASQFLLNALRQKILAERLNDGEAVKAALRSLLADLLKPLERTLVLDRAQPLVMMITGVNGAGKTTSIGK
LAQHLQRHGQSVLLAAGDTFRAAAHEQLALWGERNQINVISQQSGDPAAVIFDALNAARARKLDILMADTAGRLPTQLHL
MDELKKIKRVIGKAMHDAPHEILLVIDANTGQNALAQVKAFDDALGLTGLIVTKLDGTAKGGILAAIARQRPIPVYFIGV
GEQIDDLQPFYAEEFANALLN
MFSFFKKLHKSSTSTSELTEAENKSKNDTQDKNPPAPELTPDRPTSWVKRLKSGLAKTRNNFTNLFTNVKIDEDFFEELE
AALLMADTGLEASQFLLNALRQKILAERLNDGEAVKAALRSLLADLLKPLERTLVLDRAQPLVMMITGVNGAGKTTSIGK
LAQHLQRHGQSVLLAAGDTFRAAAHEQLALWGERNQINVISQQSGDPAAVIFDALNAARARKLDILMADTAGRLPTQLHL
MDELKKIKRVIGKAMHDAPHEILLVIDANTGQNALAQVKAFDDALGLTGLIVTKLDGTAKGGILAAIARQRPIPVYFIGV
GEQIDDLQPFYAEEFANALLN
Nucleotide
Download Length: 1026 bp
>NTDB_id=68886 MCB1EB_RS10820 WP_045364349.1 2559442..2560467(+) (pilA) [Mycoavidus cysteinexigens strain B1EB]
ATGTTTAGCTTCTTCAAAAAGCTTCATAAGAGCTCAACATCAACCTCTGAGCTCACTGAGGCAGAGAATAAATCAAAAAA
CGATACTCAGGATAAAAATCCTCCCGCCCCAGAGCTGACTCCAGATCGTCCAACCTCCTGGGTAAAACGGCTAAAATCTG
GTCTGGCGAAAACCCGTAACAACTTTACAAACCTTTTTACCAACGTCAAGATCGACGAGGATTTTTTTGAAGAACTAGAA
GCCGCTCTCTTAATGGCGGACACGGGGCTTGAAGCCAGCCAATTTTTGCTCAATGCTCTGCGCCAAAAAATCCTCGCGGA
GCGGCTTAATGACGGTGAAGCCGTCAAAGCGGCGTTACGCTCTTTATTAGCGGATTTATTAAAACCTCTTGAGCGCACAT
TAGTGCTTGACCGTGCGCAACCCTTAGTGATGATGATCACAGGTGTGAACGGCGCTGGCAAAACCACTAGCATTGGCAAA
CTCGCCCAACATTTACAGCGGCATGGACAATCTGTGTTGCTTGCCGCGGGCGACACTTTTCGCGCCGCCGCGCACGAGCA
GCTTGCGCTATGGGGCGAACGCAATCAGATTAATGTGATTTCACAGCAAAGCGGAGACCCCGCCGCAGTCATTTTCGACG
CCCTCAACGCGGCGCGCGCGCGCAAGTTAGACATCCTTATGGCGGACACCGCTGGGCGCTTGCCAACGCAATTGCATTTA
ATGGACGAGTTAAAAAAGATCAAACGCGTCATTGGCAAAGCCATGCATGACGCCCCGCATGAGATACTGCTTGTGATTGA
CGCGAATACTGGGCAGAATGCCCTCGCACAAGTCAAAGCGTTTGATGATGCGCTTGGCCTAACCGGATTGATTGTGACCA
AGCTCGACGGCACAGCGAAAGGCGGCATCCTTGCCGCAATTGCGCGACAGCGGCCGATCCCCGTCTACTTCATTGGCGTA
GGAGAACAAATTGACGATCTGCAGCCATTTTACGCCGAAGAATTCGCCAACGCGCTGCTGAATTAA
ATGTTTAGCTTCTTCAAAAAGCTTCATAAGAGCTCAACATCAACCTCTGAGCTCACTGAGGCAGAGAATAAATCAAAAAA
CGATACTCAGGATAAAAATCCTCCCGCCCCAGAGCTGACTCCAGATCGTCCAACCTCCTGGGTAAAACGGCTAAAATCTG
GTCTGGCGAAAACCCGTAACAACTTTACAAACCTTTTTACCAACGTCAAGATCGACGAGGATTTTTTTGAAGAACTAGAA
GCCGCTCTCTTAATGGCGGACACGGGGCTTGAAGCCAGCCAATTTTTGCTCAATGCTCTGCGCCAAAAAATCCTCGCGGA
GCGGCTTAATGACGGTGAAGCCGTCAAAGCGGCGTTACGCTCTTTATTAGCGGATTTATTAAAACCTCTTGAGCGCACAT
TAGTGCTTGACCGTGCGCAACCCTTAGTGATGATGATCACAGGTGTGAACGGCGCTGGCAAAACCACTAGCATTGGCAAA
CTCGCCCAACATTTACAGCGGCATGGACAATCTGTGTTGCTTGCCGCGGGCGACACTTTTCGCGCCGCCGCGCACGAGCA
GCTTGCGCTATGGGGCGAACGCAATCAGATTAATGTGATTTCACAGCAAAGCGGAGACCCCGCCGCAGTCATTTTCGACG
CCCTCAACGCGGCGCGCGCGCGCAAGTTAGACATCCTTATGGCGGACACCGCTGGGCGCTTGCCAACGCAATTGCATTTA
ATGGACGAGTTAAAAAAGATCAAACGCGTCATTGGCAAAGCCATGCATGACGCCCCGCATGAGATACTGCTTGTGATTGA
CGCGAATACTGGGCAGAATGCCCTCGCACAAGTCAAAGCGTTTGATGATGCGCTTGGCCTAACCGGATTGATTGTGACCA
AGCTCGACGGCACAGCGAAAGGCGGCATCCTTGCCGCAATTGCGCGACAGCGGCCGATCCCCGTCTACTTCATTGGCGTA
GGAGAACAAATTGACGATCTGCAGCCATTTTACGCCGAAGAATTCGCCAACGCGCTGCTGAATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilA | Neisseria gonorrhoeae MS11 |
59.935 |
90.029 |
0.54 |