Detailed information NTG0688012

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: M3N36_RS00620
• Genome accession: NZ_CP097251
• Coordinates: 102247..102681 (+)
• Length: 144 a.a.
• NCBI ID: WP_002986542.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 97247..107681

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M3N36_RS00590 (M3N36_00590)	-	98915..99280 (+)	366	WP_002986560.1	DUF1033 family protein	-
M3N36_RS00595 (M3N36_00595)	comYA	99374..100312 (+)	939	WP_030127399.1	competence type IV pilus ATPase ComGA	Machinery gene
M3N36_RS00600 (M3N36_00600)	comYB	100248..101282 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
M3N36_RS00605 (M3N36_00605)	comYC	101284..101610 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
M3N36_RS00610 (M3N36_00610)	comGD	101585..102013 (+)	429	WP_030127397.1	competence type IV pilus minor pilin ComGD	-
M3N36_RS00615 (M3N36_00615)	comGE	101970..102254 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
M3N36_RS00620 (M3N36_00620)	comYF	102247..102681 (+)	435	WP_002986542.1	competence type IV pilus minor pilin ComGF	Machinery gene
M3N36_RS00625 (M3N36_00625)	comGG	102665..102991 (+)	327	WP_002986539.1	competence type IV pilus minor pilin ComGG	-
M3N36_RS00630 (M3N36_00630)	comYH	103089..104042 (+)	954	WP_030127396.1	class I SAM-dependent methyltransferase	Machinery gene
M3N36_RS00635 (M3N36_00635)	-	104101..105297 (+)	1197	WP_011888536.1	acetate kinase	-
M3N36_RS00640 (M3N36_00640)	-	105484..105792 (+)	309	WP_030126458.1	hypothetical protein	-
M3N36_RS00645 (M3N36_00645)	proC	105875..106645 (-)	771	WP_030127395.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16573.20 Da
• Isoelectric Point: 10.3584

>NTDB_id=688012 M3N36_RS00620 WP_002986542.1 102247..102681(+) (comYF) [Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIGQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=688012 M3N36_RS00620 WP_002986542.1 102247..102681(+) (comYF) [Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAG
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTCCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGGGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	45.985	95.139	0.437
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396