Detailed information NTG0687258

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: M3M41_RS13095
• Genome accession: NZ_CP097115
• Coordinates: 2628597..2629484 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain JP18270
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2623597..2634484

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M3M41_RS13065 (M3M41_13055)	-	2623616..2623708 (+)	93	WP_010956583.1	hypothetical protein	-
M3M41_RS13070 (M3M41_13060)	-	2623816..2624313 (-)	498	WP_001065268.1	glutathione peroxidase	-
M3M41_RS13075 (M3M41_13065)	-	2624323..2624583 (-)	261	WP_001789910.1	hypothetical protein	-
M3M41_RS13080 (M3M41_13070)	-	2624965..2625078 (-)	114	WP_011447078.1	hypothetical protein	-
M3M41_RS13085 (M3M41_13075)	-	2625737..2627737 (-)	2001	WP_000776751.1	ABC transporter permease	-
M3M41_RS13090 (M3M41_13080)	-	2627734..2628489 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
M3M41_RS13095 (M3M41_13085)	braS	2628597..2629484 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
M3M41_RS13100 (M3M41_13090)	braR	2629495..2630160 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
M3M41_RS13105 (M3M41_13095)	-	2630186..2630386 (-)	201	WP_000604728.1	hypothetical protein	-
M3M41_RS13110 (M3M41_13100)	-	2630584..2632008 (+)	1425	WP_000953744.1	alkaline phosphatase	-
M3M41_RS13595	-	2632068..2632169 (-)	102	WP_000731972.1	SE2200 family small protein	-
M3M41_RS13120 (M3M41_13110)	-	2632291..2632746 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
M3M41_RS13125 (M3M41_13115)	-	2632991..2633752 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=687258 M3M41_RS13095 WP_000143419.1 2628597..2629484(-) (braS) [Staphylococcus aureus strain JP18270]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=687258 M3M41_RS13095 WP_000143419.1 2628597..2629484(-) (braS) [Staphylococcus aureus strain JP18270]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997