Detailed information NTG0687212

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: M3M42_RS09530
• Genome accession: NZ_CP097114
• Coordinates: 1927543..1928586 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain JP18269
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1922543..1933586

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M3M42_RS09500 (M3M42_09490)	-	1922961..1924217 (-)	1257	WP_001795438.1	aminopeptidase	-
M3M42_RS09505 (M3M42_09495)	-	1924220..1924420 (-)	201	WP_000180461.1	DUF1128 family protein	-
M3M42_RS09510 (M3M42_09500)	-	1924567..1925031 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
M3M42_RS09515 (M3M42_09505)	-	1925038..1925313 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
M3M42_RS09520 (M3M42_09510)	-	1925591..1926808 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
M3M42_RS09525 (M3M42_09515)	vraR	1926924..1927553 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
M3M42_RS09530 (M3M42_09520)	vraS	1927543..1928586 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
M3M42_RS09535 (M3M42_09525)	liaF	1928583..1929284 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
M3M42_RS09540 (M3M42_09530)	-	1929299..1929685 (-)	387	WP_001110179.1	hypothetical protein	-
M3M42_RS09545 (M3M42_09535)	map	1929902..1930660 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
M3M42_RS09550 (M3M42_09540)	-	1931188..1932174 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
M3M42_RS09555 (M3M42_09545)	-	1932605..1933018 (-)	414	WP_001549145.1	hypothetical protein	-
M3M42_RS09560 (M3M42_09550)	-	1933047..1933157 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=687212 M3M42_RS09530 WP_001017131.1 1927543..1928586(-) (vraS) [Staphylococcus aureus strain JP18269]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=687212 M3M42_RS09530 WP_001017131.1 1927543..1928586(-) (vraS) [Staphylococcus aureus strain JP18269]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1